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Displaying drugs 351 - 375 of 727 in total
C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational
Matched Synonyms: … , non-replicating lentiviral vector, encoding a bispecific chimeric antigen receptor targeting CD19 and
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … 6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa
Matched Description: … [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name ... bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant ... A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … CUBICIN® 350 MG POLVO PARA SOLUCIÓN INYECTABLE O INFUSIÓN ... CUBICIN® 500 MG POLVO PARA SOLUCION INYECTABLE O INFUSION ... DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL …
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids ... , ammonium, potassium or sodium salts or as acid amides. ... Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. …
Matched Mixtures name: … Kaolin and Pectin Susp ... Cepacol Sore Throat and Coating ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Compounds used in a research, industrial, or household setting …
Matched Products: … Ludens Honey and Berry …
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … characterized by the oversecretion of gastric acid. ... of many other proton pump inhibitor drugs [A174232]. ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults …
Matched Mixtures name: … Zegerid OTC ... Zegerid OTC ... Zegerid OTC
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin ... omeprazole, amoxicillin and metronidazole ... omeprazole, amoxicillin and clarithromycin …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... Foster and Thrive Omeprazole …
Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III (APOC3).
Investigational
Matched Synonyms: … DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O- ... (2-METHOXYETHYL)-P-THIOADENYLYL-(3'-O->5'-O)-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3 ... M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETH …
Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug...
Approved
Matched Synonyms: … 6-O-methyl erythromycin ... 6-O-methylerythromycin ... 6-O-methylerythromycin A …
Matched Iupac: … (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy ... }-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy …
Matched Description: … Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration ... translation and protein assembly process. ... Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Alimentary Tract and Metabolism ... Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … KLARICID® OD ... KLARICID O.D. ... Clarie OD Tablets 500mg …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Isoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein VTE in Colorectal Cancer, among others.
Investigational
Matched Synonyms: … Quercetin-3-O-glucoside ... Quercetin 3-O-glucopyranoside …
Matched Iupac: … }-4H-chromen-4-one ... 3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy
Matched Description: … Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein VTE ... Isoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced …
Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies...
Approved
Investigational
Matched Description: … Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally ... [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective ... at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Alimentary Tract and Metabolism ... lansoprazole, amoxicillin and levofloxacin ... lansoprazole, clarithromycin and tinidazole ... lansoprazole, amoxicillin and metronidazole ... lansoprazole, tetracycline and metronidazole …
Matched Products: … Up and Up Lansoprazole ... Berkley and Jensen Lansoprazole ... Foster and Thrive Acid Reducer …
This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a dip or wash. Coumaphos is widely used for both farm and domestic animals to control ticks, mites, flies and fleas.
Vet approved
Matched Synonyms: … O-(3-chloro-4-methyl-2-oxo-2H-chromen-7-yl) O,O-diethyl thiophosphate ... O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl)phosphorothioate ... Phosphorothioic acid, O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl ester …
Matched Iupac: … O-3-chloro-4-methyl-2-oxo-2H-chromen-7-yl O,O-diethyl phosphorothioate …
Matched Description: … It is non-volatile in nature and is well known by a variety of names as such a _dip_ or _wash_. ... Coumaphos is widely used for both farm and domestic animals to control ticks, mites, flies and fleas. ... This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... commonly treated with transurethral resection of the bladder tumour and Bacillus Calmette-Guérin (BCG ... It is one of the active ingredients in Anktiva, a combination product also containing [inbakicept], where …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
Investigational
Matched Synonyms: … DNA, D((2'-O-(2-METHOXYETHYL))M5RU-SP-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O- ... -(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL) ... (2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RA-SP-G-SP-T-SP-M5C-SP-T-SP-M5C-SP-T-SP-T-SP-G-SP-G-SP-M5C-SP …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Description: … consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta ... The alpha- and beta- subunits have 92 and 111 amino acids. ... 7 and Asn 24. …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu ... MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … GONAL-F® 450 IU/0.75 ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GONAL-F® 75 IU (5.5MCG) POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Iupac: … 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid …
Matched Description: … and easier to pass [L1801]. ... Docusate is on the World Health Organization's List of Essential Medicines[L5915]. ... Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[ …
Matched Mixtures name: … Re Ob 90 DHA ... Folet One ... Pnv Ob DHA …
Matched Categories: … Alimentary Tract and Metabolism ... Softener and Emollient Laxatives …
Matched Products: … Up and up stool softener ... Stool Softener easy and gentle …
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Description: … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... in the UK in 1969 and USA in 1974. ... Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered …
Matched Mixtures name: … Care One Ibuprofen Cold and Sinus ... Meds on the Go ... Care One Ibuprofen PM …
Matched Categories: … Ibuprofen and isomer ... codeine and ibuprofen ... oxycodone and ibuprofen ... hydrocodone and ibuprofen ... Antiinflammatory and Antirheumatic Products …
Matched Products: … Up and Up Ibuprofen ... Pain and Fever ... Up and Up Ibuprofen Junior …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Iupac: … -5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium ... -7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato-8-oxo
Matched Description: … essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Iupac: … (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-1-(2-chloroacetyl)-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H, …
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different …
Matched Categories: … formoterol and mometasone …
Matched Products: … Up and Up Allergy ... Nasonex Allergy and Congestion ... Nasal Allergy and Congestion Relief …
Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
Investigational
Vet approved
Matched Iupac: … 5S,6S,7R,9R,11E,13E,15R,16R)-6-{[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy ... dimethylpiperidin-1-yl]ethyl}-16-ethyl-4-hydroxy-15-({[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxy
Matched Description: … It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory …
Matched Products: … Tilmovet® 200 g/kg Premix for Medicated Feeding Stuff for Pigs and Rabbits ... OMS TILMI 250MG/ML ORAL SOLUTION ... OMS TILMICOSIN 200MG/G PREMIX POWDER …
Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... , such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote ... and accelerated re-epithelialization in wound healing. …
Matched Mixtures name: … Somarexin and C 1000 ... B Complex W C and B12 Inj ... CH6 Perfumed Aloforthya Peony and the sunset …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Amino Acids, Peptides, and Proteins …
Matched Products: … Eros Aqua Sensations and Care Woman …
Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … REMIFENTANILO 2MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE O INFUSION INTRAVENOSA ... Remifentanil Reig Jofre 5mg Powder for Concentrate for Solution for Injection or Infusion ... REMIFENTANILO 5MG POLVO POLVO LIOFILIZADO PARA SOLUCIÓN INYECTABLE O INFUSIÓN INTRAVENOSA. …
Approved
Matched Synonyms: … O-formylcefamandole …
Matched Iupac: … -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... -7-[(2R)-2-(formyloxy)-2-phenylacetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Description: … It is the principal end product of protein catabolism and constitutes about one half of the total urinary ... A compound formed in the liver from ammonia produced by the deamination of amino acids. …
Matched Mixtures name: … Hydrophil Ont
Matched Categories: … Blood and Blood Forming Organs ... Emollients and Protectives ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Carb-O-Philic ... U O CREAM 10% …
Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem]
Experimental
Matched Name: … 1-O-[O-Nitrophenyl]-Beta-D-Galactopyranose …
Matched Description: … Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem] …
Displaying drugs 351 - 375 of 727 in total