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Displaying drugs 351 - 375 of 12677 in total
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. Tropisetron appears to be well tolerated with the most frequently reported adverse effect being headache. Extrapyramidal...
Approved
Investigational
Matched Description: … receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring
Approved
Experimental
Investigational
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Description: … Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype ... antiviral agent against the hepatitis C virus. ... 1 for the treatment of chronic hepatitis C virus (HCV) infection. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Heterocyclic Compounds, Fused-Ring
Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. …
Miglitol inhibits the breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body. Miglitol should be taken at the start...
Approved
Matched Description: … It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing ... of a meal for maximal effect and the effect will depend on the amount of poly and oligosaccharides in
Matched Categories: … Drugs Used in Diabetes ... Heterocyclic Compounds, 1-Ring
Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging from hormonal contraception to the treatment of menopausal symptoms. Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. It is more potent and...
Approved
Investigational
Matched Description: … product in the world. ... [L33179] In Canada, Nextstellis was approved for use in March 2021; it was developed by Mithra and is ... [L33179] It is more potent and is safer than the synthetic estrogen ethinylestradiol (EE2) found in 97% …
Matched Categories: … Fused-Ring Compounds …
Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. Atezolizumab was granted...
Approved
Investigational
Matched Description: … antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in ... [L7489] In November 2022, the manufacturer (Genentech) voluntarily withdrew the use of atezolizumab for …
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Description: … Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart …
Matched Categories: … Fused-Ring Compounds ... Compounds used in a research, industrial, or household setting …
Renal cell carcinoma (RCC) is responsible for 3% of cancer cases and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74. Tivozanib, also known as FOTIVDA, is a kinase inhibitor developed to treat adult patients with relapsed or...
Approved
Investigational
Matched Description: … carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common cancers in
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring
Azadirachta indica leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Azadirachta indica leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression...
Approved
Investigational
Matched Description: … Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to ... and suppression of bacterial growth in several microbiological media. ... The clinical applications of rose bengal as injectable formulation under the name PV-10 in melanoma, …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Heterocyclic Compounds, 3-Ring ... Heterocyclic Compounds, Fused-Ring
Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Description: … [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring
Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … Ni-C-E-LE Plus ... Chela Iron Plus C,b Complex ... FLAVETTES DAILY PLUS TABLET F/C
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there ... Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus ... interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. …
Matched Mixtures name: … ZYMAFLUOR D 500 C C ... C & D ... C-Nate DHA …
Matched Categories: … Fused-Ring Compounds …
Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Matched Description: … In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring
Ecamsule is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability. Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only...
Approved
Matched Description: … in a few products manufactured by L'Oreal. ... Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only …
Matched Mixtures name: … Anthelios XL Melt-IN Cream …
Matched Categories: … Bridged-Ring Compounds ... Compounds used in a research, industrial, or household setting …
Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain,...
Approved
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring
A benzodiazepine derivative used mainly as a hypnotic.
Approved
Illicit
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring
Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Description: … invasive candidiasis in adults with limited or no alternative treatment options. ... It can only be administered intravenously but does not reach therapeutic concentrations in the central ... [A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and …
Matched Categories: … Heterocyclic Compounds, 1-Ring
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including plastics, pesticides, pharmaceuticals, disinfectants, and dyes. Ingestion of cresol induces toxicity...
Approved
Matched Description: … At concentrations normally found in the environment however, cresols do not pose any significant risk ... Ingestion of cresol induces toxicity in humans and can lead to burning of the mouth and throat, abdominal …
Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted photodynamic therapy for malignancies. Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a focal treatment for localized prostate cancer. It aims to destroy only cancerous lesions of the prostate, rather than ablating the entire prostate gland. Padeliporfin...
Approved
Experimental
Matched Description: … approved by the European Commission on November 10, 2017, for the treatment of low-risk prostate cancer in
Matched Categories: … Sensitizers Used in Photodynamic/radiation Therapy ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, Fused-Ring
Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Description: … Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for ... They are available in an assortment of tablet, injection, and other forms, depending on the setting and …
Matched Mixtures name: … C. Vit-min Formula ... Cal & Mag Hvp Chel Plus C Potass & Zinc Tab ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET …
Displaying drugs 351 - 375 of 12677 in total