Displaying drugs 3801 - 3825 of 4648 in total
5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE
Experimental
Matched Name: … 5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE …
Matched Iupac: … (5Z)-5-[(quinoxalin-6-yl)methylidene]-1,3-thiazolidine-2,4-dione …
Matched Iupac: … (5Z)-5-[(quinoxalin-6-yl)methylidene]-1,3-thiazolidine-2,4-dione …
2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL
Experimental
Matched Name: … 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL …
Matched Iupac: … 2-(4-hydroxyphenyl)-1-benzofuran-5-ol …
Matched Iupac: … 2-(4-hydroxyphenyl)-1-benzofuran-5-ol …
2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE
Experimental
Matched Name: … 2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE …
Matched Iupac: … 2-(2-methylphenyl)-1H-indole-5-carboximidamide …
Matched Iupac: … 2-(2-methylphenyl)-1H-indole-5-carboximidamide …
Inosine pranobex
Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy ... -5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one …
Matched Description: … and dimethylaminoisopropanol used as an antiviral drug. ... Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … IMIN TABLETS 500 mg ... ISOPRINOSINE TABLET 500 mg ... VELP 500 MG TABLET, 10 ADET …
Matched Description: … and dimethylaminoisopropanol used as an antiviral drug. ... Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … IMIN TABLETS 500 mg ... ISOPRINOSINE TABLET 500 mg ... VELP 500 MG TABLET, 10 ADET …
Suzetrigine
Suzetrigine is under investigation in clinical trial NCT05558410 (Evaluation of Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty).
Investigational
Matched Synonyms: … 4-[[[(2R,3S,4S,5R)-3-(3,4-Difluoro-2-methoxyphenyl)tetrahydro-4,5-dimethyl-5-(trifluoromethyl)-2-furanyl …
Matched Description: … Suzetrigine is under investigation in clinical trial NCT05558410 (Evaluation of Efficacy and Safety of ... VX-548 for Acute Pain After an Abdominoplasty). …
Matched Description: … Suzetrigine is under investigation in clinical trial NCT05558410 (Evaluation of Efficacy and Safety of ... VX-548 for Acute Pain After an Abdominoplasty). …
Irbesartan
Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Matched Synonyms: … 2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one …
Matched Iupac: … 2-butyl-3-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4- …
Matched Mixtures name: … APROVASC® 150MG/5MG ... APROVASC® 300MG/5MG ... IRBESARTÁN 150 MG / AMLODIPINO 5 MG …
Matched Salts name: … Irbesartan hydrochloride …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... irbesartan and diuretics ... irbesartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and diuretics ... irbesartan, amlodipine and hydrochlorothiazide …
Matched Iupac: … 2-butyl-3-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4- …
Matched Mixtures name: … APROVASC® 150MG/5MG ... APROVASC® 300MG/5MG ... IRBESARTÁN 150 MG / AMLODIPINO 5 MG …
Matched Salts name: … Irbesartan hydrochloride …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... irbesartan and diuretics ... irbesartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and diuretics ... irbesartan, amlodipine and hydrochlorothiazide …
(R)-Gossypol
(R)-Gossypol is the R-isomer of Gossypol.
Investigational
Matched Synonyms: … (r)-2,2'-bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) …
Matched Iupac: … 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(propan-2-yl)-[2,2'-binaphthalene]-8,8'-dicarbaldehyde …
Matched Iupac: … 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(propan-2-yl)-[2,2'-binaphthalene]-8,8'-dicarbaldehyde …
ATM-3507
Investigational
Matched Synonyms: … (3-((2,3-dimethyl-1-(3-(4-methylpiperazin-1-yl)propyl)-1h-indol-5-yl)oxy)phenyl)(4-(4-fluorophenethyl ... Methanone, (3-((2,3-dimethyl-1-(3-(4-methyl-1-piperazinyl)propyl)-1h-indol-5-yl)oxy)phenyl)(4-(2-(4-fluorophenyl …
Matched Iupac: … 5-(3-{4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl}phenoxy)-2,3-dimethyl-1-[3-(4-methylpiperazin- …
Matched Iupac: … 5-(3-{4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl}phenoxy)-2,3-dimethyl-1-[3-(4-methylpiperazin- …
Inobrodib
Investigational
Matched Synonyms: … (s)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4s)-4-methoxycyclohexyl)-1h-benzo( ... 2-piperidinone, 1-(3,4-difluorophenyl)-6-(5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl) …
SP2456
Experimental
Matched Synonyms: … (2R)-2-Cyclohexyl-2-(diaminomethylideneamino)-N-[2-[4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin …
Matched Iupac: … (2R)-2-cyclohexyl-2-[(diaminomethylidene)amino]-N-(2-{4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin …
Matched Iupac: … (2R)-2-cyclohexyl-2-[(diaminomethylidene)amino]-N-(2-{4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin …
ADH-1
Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Synonyms: … l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide …
Matched Description: … and organisms. ... well-defined shape and become loosely adherent, flattened and migratory. ... Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and …
Matched Description: … and organisms. ... well-defined shape and become loosely adherent, flattened and migratory. ... Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and …
Dezapelisib
Dezapelisib is under investigation in clinical trial NCT02456675 (INCB040093 and INCB040093 Combined With Itacitinib (INCB039110) in Relapsed/refractory Hodgkin Lymphoma).
Investigational
Matched Synonyms: … 6-(3-fluorophenyl)-3-methyl-7-[(1S)-1-(7H-purin-6-ylamino)ethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one …
Matched Iupac: … 6-(3-fluorophenyl)-3-methyl-7-[(1S)-1-[(9H-purin-6-yl)amino]ethyl]-5H-[1,3]thiazolo[3,2-a]pyrimidin-5 …
Matched Description: … Dezapelisib is under investigation in clinical trial NCT02456675 (INCB040093 and INCB040093 Combined …
Matched Iupac: … 6-(3-fluorophenyl)-3-methyl-7-[(1S)-1-[(9H-purin-6-yl)amino]ethyl]-5H-[1,3]thiazolo[3,2-a]pyrimidin-5 …
Matched Description: … Dezapelisib is under investigation in clinical trial NCT02456675 (INCB040093 and INCB040093 Combined …
Zalcitabine
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Synonyms: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
RWJ-56423
Experimental
Matched Synonyms: … (2S,4R)-1-acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-hydroxypyrrolidine …
Matched Iupac: … (2S,4R)-1-acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl]-4- …
Matched Iupac: … (2S,4R)-1-acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl]-4- …
Fosmanogepix
Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
Investigational
Matched Synonyms: … [2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen …
Matched Iupac: … amino-1-[(hydrogen phosphonatooxy)methyl]-3-[3-({4-[(pyridin-2-yloxy)methyl]phenyl}methyl)-1,2-oxazol-5- …
Matched Description: … Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 …
Matched Iupac: … amino-1-[(hydrogen phosphonatooxy)methyl]-3-[3-({4-[(pyridin-2-yloxy)methyl]phenyl}methyl)-1,2-oxazol-5- …
Matched Description: … Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 …
ENMD-981693
Investigational
Matched Synonyms: … (E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine …
Matched Iupac: … N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-[(1E)-2-phenylethenyl]pyrimidin-4-amine …
Matched Iupac: … N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-[(1E)-2-phenylethenyl]pyrimidin-4-amine …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Lerodalcibep
Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patients).
Investigational
Matched Synonyms: … 9 ligand-binding tenth fibronectin type iii domain) fusion protein with peptide (synthetic 6-amino acid …
Matched Description: … of LIB003 and Inclisiran in High-risk CVD Patients). ... Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety …
Matched Description: … of LIB003 and Inclisiran in High-risk CVD Patients). ... Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety …
Nitroprusside
Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … and venules (venules more than arterioles). ... Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles …
Matched Categories: … Indicators and Reagents ... Nitrates and Nitrites ... Iron Compounds ... Nitric Oxide Donors …
Matched Products: … NIPRUSS AMPUL, 5 ADET ... NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE ... Nitroprussid-Natrium AraMed 50 mg/2 ml Infusionslösung …
Matched Categories: … Indicators and Reagents ... Nitrates and Nitrites ... Iron Compounds ... Nitric Oxide Donors …
Matched Products: … NIPRUSS AMPUL, 5 ADET ... NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE ... Nitroprussid-Natrium AraMed 50 mg/2 ml Infusionslösung …
Befotertinib
Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive Patients With Advanced Egfr-mutant Lung Cancer).
Investigational
Matched Synonyms: … 2-propenamide, n-(2-((2-(dimethylamino)ethyl)methylamino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1h-indol ... N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1h-indol-3-yl) …
Matched Description: … Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive …
Matched Description: … Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive …
Succinylcholine
Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups. It has been widely used for over 50 years, most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. Its...
Approved
Matched Description: … Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and ... a means of neuromuscular blockade during intubation and surgical procedures. ... [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Products: … Lysthenon 0,1 g/5 ml - Injektionslösung …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Products: … Lysthenon 0,1 g/5 ml - Injektionslösung …
Methotrimeprazine
A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Description: … A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine …
Matched Salts name: … Methotrimeprazine hydrochloride …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … Methotrimeprazine-5 ... Methotrimeprazine-50 ... Novo Meprazine Tab 5mg …
Matched Salts name: … Methotrimeprazine hydrochloride …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … Methotrimeprazine-5 ... Methotrimeprazine-50 ... Novo Meprazine Tab 5mg …
4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-Amide
Experimental
Matched Name: … 4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl …
Matched Iupac: … hex-1-en-3-yl]-2-({hydroxy[4-(morpholin-4-yl)piperidin-1-yl]methylidene}amino)-3-phenylpropanimidic acid …
Matched Iupac: … hex-1-en-3-yl]-2-({hydroxy[4-(morpholin-4-yl)piperidin-1-yl]methylidene}amino)-3-phenylpropanimidic acid …
3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID
Experimental
Matched Name: … 3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID …
Matched Iupac: … (3S)-3-[(2R)-6-[(8-hydroxyquinolin-2-yl)formamido]-2-(thiophen-2-yl)hexanamido]-4-oxobutanoic acid …
Matched Iupac: … (3S)-3-[(2R)-6-[(8-hydroxyquinolin-2-yl)formamido]-2-(thiophen-2-yl)hexanamido]-4-oxobutanoic acid …
Brinzolamide
Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities.[A2049,A2051] The resulting vascular...
Approved
Matched Description: … ], the first-ever approved topical CA inhibitor with contrasting results and evidence. ... pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and ... [A2049,A2051]
Brinzolamide was developed as a topical solution to the systemic side effects and [dorzolamide …
Matched Mixtures name: … AZARGA 10 MG/ML+5 MG/ML STERİL SÜSPANSİYON GÖZ DAMLASI, 5 ML ... AZARGA 10MG/ML+5MG/ML ... AZARGA 10MG/ML + 5MG/ML …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … AZOPT % 1 STERİL OFTALMİL SÜSPANSİYON,GÖZ DAMLASI, SÜSPANSİYON, 5 ML …
Matched Mixtures name: … AZARGA 10 MG/ML+5 MG/ML STERİL SÜSPANSİYON GÖZ DAMLASI, 5 ML ... AZARGA 10MG/ML+5MG/ML ... AZARGA 10MG/ML + 5MG/ML …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … AZOPT % 1 STERİL OFTALMİL SÜSPANSİYON,GÖZ DAMLASI, SÜSPANSİYON, 5 ML …
Displaying drugs 3801 - 3825 of 4648 in total