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Displaying drugs 376 - 400 of 8243 in total

Glycerol phenylbutyrate

Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Approved
Matched Synonyms: … Glyceryl Tri-4-Phenylbutyrate …
Matched Iupac: … 1,3-bis[(4-phenylbutanoyl)oxy]propan-2-yl 4-phenylbutanoate …

Labetalol

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide ... 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Salts cas: … 32780-64-6 …
Matched Products: … LABLOL 100 MG/20 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... LABETALOL HIDROCLORURO 5 MG/ML SOLUCIÓN INYECTABLE ... BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …

Secnidazole

Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2­ hydroxypropyl)-2-methyl-5-nitroimidazole ... 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2­ ol …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. ... It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays …
Matched Products: … SECNIDOX 1000 MG FILM TABLET,4 ADET ... FLAGENTYL 500 MG FİLM KAPLI TABLET, 4 ADET ... SECNIDOX 500 MG FILM TABLET ,4 FILM TABLET …

Remestemcel-L

Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Description: … refractory aGvHD that do not respond to steroid therapy have expected one-year survival rates of only 5% …

Nirsevimab

Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational

Calcium phosphate dihydrate

Approved

Midodrine

An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Synonyms: … 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol …
Matched Products: … MIDODRINA 5 MG ... GUTRON TABLET 5 mg ... Gutron 5 mg - Tabletten …

Fosdenopterin

Molybdenum cofactor deficiency (MoCD) is an exceptionally rare autosomal recessive disorder resulting in a deficiency of three molybdenum-dependent enzymes: sulfite oxidase (SOX), xanthine dehydrogenase, and aldehyde oxidase. Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites resulting from a lack of SOX activity.[A230088,L32163]...
Approved

Tropisetron

Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. Tropisetron appears to be well tolerated with the most frequently reported adverse effect being headache. Extrapyramidal...
Approved
Investigational
Matched Salts cas: … 105826-92-4 …
Matched Categories: … Serotonin 5-HT3 Receptor Antagonists …
Matched Products: … NAVOBAN 5 MG 1 AMPUL ... Navoban 5 mg - Kapseln ... Navoban 5 mg - Ampullen …

Zilucoplan

Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … .-(2-(((4S)-4-CARBOXY-1-OXO-4-(1-OXOHEXADECYL)BUTYL)AMINO)ETHYL)-.OMEGA. …
Matched Iupac: … )propanoyl]pyrrolidin-2-yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy-4-hexadecanamidobutanamido ... -2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11-benzyl-8-(3-carbamimidamidopropyl)-5- ... hydroxyphenyl)propanamido]-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]-3-(4-hydroxyphenyl ... 1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido]-3-(4- …
Matched Description: … [L48701] It was also later approved by the EMA on December 4, 2023, as an add-on treatment for the same …

Technetium Tc-99m mebrofenin

Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved

Human papillomavirus type 58 L1 capsid protein antigen

Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Products: … 6-UR ... LEVEBRAIN 100MG/ML ORAL ÇÖZELTI,5 ML ENJEKTÖR+150 ML ... EPILECURE 500 MG/5 ML KONSANTRE INFÜZYON ÇÖZELTISI,10 ADET …

Articaine

Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Approved
Matched Iupac: … methyl 4-methyl-3-[2-(propylamino)propanamido]thiophene-2-carboxylate …
Matched Mixtures name: … ULTRACAIN DS 40 MG/Ml+6 MCG/ML ENJEKSİYONLUK ÇÖZELTİ, 20 AMPUL ... Orabloc 40 mg/ml + 5 Mikrogramm/ml Injektionslösung ... Ubistesin 40 mg/ml + 5 Mikrogramm/ml - Injektionslösung …

Loxoprofen

Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina. A transdermal preparation was approved for use in Japan in January 2006.
Approved
Matched Iupac: … 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid …
Matched Salts cas: … 80382-23-6 …

Human varicella-zoster immune globulin

Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Description: … The therapeutic efficacy is proven if administered within 4 days of exposure to varicella zoster virus …

Masoprocol

A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Synonyms: … meso-4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol …
Matched Iupac: … 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol …

Oxybutynin

Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Synonyms: … 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat ... 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate ... 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester …
Matched Iupac: … 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate …
Matched Products: … VOXET 5 MG /5 ML ŞURUP,100 ML ... MUTUM JARABE 5 MG / 5 ML. ... OXYBUGAMMA 5 …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … 15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6- …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Synonyms: … Exendin 4 ... Exendin-4 ... Synthetic exendin-4 …
Matched Products: … BYETTA 5 µG/20 µL SC KULLANIMA HAZIR DOLU ENJEKSİYON KALEMI ICINDE COZELTI, 1.2 ML (60 DOZ) …

Alfacalcidol

Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene] ... ethylidene}-4-methylidenecyclohexane-1,3-diol …

Indacaterol

Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Iupac: … 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1,2-dihydroquinolin …

Pretomanid

Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. Research in recent years has been geared toward the development of novel therapies that target persistent forms of this disease, which have shown resistance to standard therapy...
Approved
Matched Iupac: … (6S)-2-nitro-6-{[4-(trifluoromethoxy)phenyl]methoxy}-5H,6H,7H-imidazo[2,1-b][1,3]oxazine …

Crizotinib

Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic large cell lymphoma (ALCL) and inflammatory myofibroblastic tumor (IMT). By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, crizotinib offers...
Approved
Investigational
Matched Iupac: … 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine …
Matched Description: … [L42460] By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, …

Glutamic acid

A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Mixtures name: … Aminosyn II 5% Inj ... AMINOPLASMAL-5% E INFUSION ... PF PEDIATRIAMINE %6 AMINO ASIT I.V INFÜZYON IÇIN ÇÖZELTI ,500 ML SETLI …
Displaying drugs 376 - 400 of 8243 in total