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Displaying drugs 376 - 400 of 11832 in total
Sevoflurane
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Description: … [L42340] Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved ... by the FDA in 1996. ... [A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety …
Relugolix
Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions. It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment of uterine fibroids, and more recently by the United States' FDA in 2020, under the brand name...
Approved
Investigational
Matched Description: … It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment ... [L27996] In addition to its relative ease-of-use, relugolix was shown to be superior in the depression ... [L42150] Relugolix has also been studied in the symptomatic treatment of endometriosis. …
Bromocriptine
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Matched Description: … In 1995, the FDA withdrew the approval of bromocriptine mesylate for the prevention of physiological ... pulmonary fibrosis, and can also cause sustained suppression of somatotropin (growth hormone) secretion in …
Tannic acid
Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine....
Approved
Matched Description: … In the old days it was used as antidote against different poisons. ... Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Hydroxyethyl cellulose
Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as...
Approved
Matched Description: … It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its ... and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic ... It is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Clofarabine
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. ... Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been …
Methimazole
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options ... of methimazole appears to be unclear[A184643,A184757,A184763] and its place in therapy may change in ... [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now …
Ivosidenib
Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of cancer cells. Ivosidenib was granted accelerated approval by the FDA...
Approved
Investigational
Matched Description: … relapsed of refractory acute myeloid leukemia in adults. ... [L46287] It was fully approved by the EMA in May 2023.[L46596] ... Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. …
Lemborexant
Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits,...
Approved
Investigational
Matched Description: … Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized ... [L10863] Recent research in the field of sleep disorders has revealed that insomnia is likely driven …
Icodextrin
Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport...
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Influenza B virus B/Maryland/15/2016 BX-69A antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Influenza B virus B/Hubei-Wujiagang/158/2009 BX-39 antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Influenza B virus B/Austria/1359417/2021 BVR-26 antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in ... Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen in …
Strontium ranelate
Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Description: … It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in treatment of severe ... of strontium ranelate to improve and strengthen intrinsic bone tissue quality and microarchitecture in ... Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) …
Lactitol
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Description: … chronic idiopathic constipation in February 2020. ... the treatment of hepatic encephalopathy in patients with cirrhosis. ... [A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Agalsidase alfa
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Description: … a contamination event in 2009. ... [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after ... While patients generally do not experience a clinically significant difference in outcomes between the …
Varenicline
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. ... Food and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, ... The FDA said it is keeping the black box in place at least until the results of the trial are announced …
Matched Categories: … Drugs Used in Addictive Disorders ... Drugs Used in Nicotine Dependence …
Matched Categories: … Drugs Used in Addictive Disorders ... Drugs Used in Nicotine Dependence …
Racemethionine
A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.
Approved
Experimental
Matched Mixtures name: … C. Vit-min Formula …
Bimatoprost
Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as...
Approved
Investigational
Matched Description: … in 2008, as eyelash growth became a desirable adverse effect for patients using this drug. ... Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. ... It has the ability to reduce ocular hypotension, proving effective in conditions such as ocular hypertension …
Matched Mixtures name: … TRIPLIGAN C …
Matched Mixtures name: … TRIPLIGAN C …
Cisatracurium
Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in ... Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in …
Azacitidine
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … by the FDA in September 2020. ... It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity ... [A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved …
Brilliant green cation
Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool. Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.
Approved
Vet approved
Matched Description: … Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Drometrizole trisiloxane
Drometrizole trisiloxane is a photostable UVA and UVB light filter [A33069, L2780, L2781, L2782, L2783, F81]. The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and Japan, among other countries....
Approved
Matched Description: … XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in ... Despite being used elsewhere in the world with relatively few reports of adverse reactions, the FDA continues …
Matched Mixtures name: … Anthelios XL Melt-IN Cream …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Anthelios XL Melt-IN Cream …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Omaveloxolone
Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational
Matched Description: … in adults and adolescents aged 16 years and older. ... In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 ... Therefore, the use of Nrf2 activators such as omaveloxolone represents a therapeutic advantage in this …
Displaying drugs 376 - 400 of 11832 in total