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Displaying drugs 376 - 400 of 14787 in total

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … the eye, ear, nose, and throat. ... It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Categories: … Analgesics and Anesthetics …

Plicamycin

Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued plicamycin in 2000.
Approved
Investigational
Withdrawn
Matched Description: … It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management …
Matched Categories: … Indicators and Reagents ... Calcium-Regulating Hormones and Agents ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …

Latanoprost

Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse …
Matched Mixtures name: … Latanoprost and Timolol Ophthalmic Solution ... Latanoprost and Timolol STADA 50mcg/ml + 5mg/ml Eye drops ... LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPS …
Matched Categories: … latanoprost and netarsudil ... Antiglaucoma Preparations and Miotics …

N-acetyltyrosine

N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Permethrin

A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. …
Matched Categories: … Scabicides and Pediculicides ... Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …

Phenylpropanolamine

Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Approved
Vet approved
Withdrawn
Matched Description: … It has been used as a decongestant and appetite suppressant. ... Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and ... Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic …
Matched Mixtures name: … Counteract Sinus and Allergy ... Triaminic Cold and Allergy Syrup ... Contac Cough Cold and Flu Caplets …

Mephenesin

Mephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis via central nervous system depression . It first entered use in the 1950s.
Approved
Matched Description: … Mephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis …

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no ... choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and …
Matched Products: … Levetiracetam in Sodium Chloride …

Enalaprilat

Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ferrous gluconate

Approved
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement …
Matched Categories: … Blood and Blood Forming Organs ... ferrous gluconate and folic acid …

Deflazacort

Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD). It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA.[L6694,FDA label] Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which...
Approved
Investigational
Matched Description: … This disease can cause serious muscle weakness and progressive breathing and cardiovascular disability ... , severely impacting patient quality of life and survival. ... It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA. …
Matched Categories: … Sex Hormones and Insulins ... Corticosteroid Hormone Receptor Agonists …

Phylloquinone

Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Description: … precursors to coagulation factors II, VII, IX, and X. ... [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates ... the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and …
Matched Mixtures name: … Vitamin D2 and K1 ... NUTRILITE CHILDREN MULTIVITAMIN AND IRON CHEWABLE TABLET …
Matched Categories: … Diet, Food, and Nutrition ... Blood and Blood Forming Organs …

Acetic acid

Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or...
Approved
Matched Description: … It is used locally, occasionally internally, as a counterirritant and also as a reagent. ... Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. …
Matched Mixtures name: … Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid …
Matched Categories: … Indicators and Reagents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Bos taurus skin

Bos taurus skin or pelt is used in allergenic testing.
Approved
Matched Mixtures name: … Cattle Hair and Epithelia …

Sus scrofa skin

Sus scrofa skin or pelt is used in allergenic testing.
Approved
Matched Mixtures name: … Hog Hair and Epithelia …

Olsalazine

Olsalazine is an aminosalicylate and a prodrug of mesalamine (5-aminosalicylic acid, 5-ASA). It was first developed for delivering mesalamine to the colon without the use of sulfapyridine. Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon. Olsalazine is an anti-inflammatory agent that works...
Approved
Matched Description: … Olsalazine is an aminosalicylate and a prodrug of [mesalamine] (5-aminosalicylic acid, 5-ASA). ... , subsequently reducing the production of pro-inflammatory factors like prostaglandin and leukotriene ... [A257078] Olsalazine is an anti-inflammatory agent that works by inhibiting cyclooxygenase and lipoxygenase …
Matched Salts name: … Olsalazine sodium …
Matched Categories: … Alimentary Tract and Metabolism …

Methylparaben

Methylparaben is used in allergenic testing.
Approved
Matched Salts name: … Methylparaben sodium …

Paspalum notatum pollen

Paspalum notatum pollen is the pollen of the Paspalum notatum plant. Paspalum notatum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Southeastern Grasses …

Phalaris arundinacea pollen

Phalaris arundinacea pollen is the pollen of the Phalaris arundinacea plant. Phalaris arundinacea pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Secale cereale pollen

Secale cereale pollen is the pollen of the Secale cereale plant. Secale cereale pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Eprosartan

Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Categories: … eprosartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics …

Vernakalant

Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates. Intravenous formulation was approved in Europe in September 2010 as Brinavess and...
Approved
Investigational
Matched Description: … Intravenous formulation was approved in Europe in September 2010 as Brinavess and in Canada in April …

Vibrio cholerae Ogawa 50 classical biotype, formalin inactivated

Approved
Matched Mixtures name: … DUKORAL VACCINE AGAINST CHOLERA AND ETEC-DIARRHOEA …

Dofetilide

Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Approved
Investigational
Matched Description: … flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter. ... Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration ( ... FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and …

Danaparoid

Danaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans . The active constituents are heparan, dermatan and DB09301 , and they are isolated from the porcine intestinal mucosa [FDA Label]. Danaparoid possesses a potent antithrombic activity that works by inhibiting...
Approved
Withdrawn
Matched Description: … Danaparoid sodium is the common salt form in therapeutic preparations and is typically administered subcutaneously ... The active constituents are heparan, dermatan and [DB09301] [T28], and they are isolated from the porcine ... in the United States however it is available in several other countries including European countries and …
Matched Salts name: … Danaparoid sodium …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Displaying drugs 376 - 400 of 14787 in total