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Displaying drugs 376 - 400 of 14523 in total

Sorbitol

A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Approved
Matched Description: … It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for ... Sorbitol occurs naturally and is also produced synthetically from glucose. …
Matched Mixtures name: … Cleanse Gut And Colon ... INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) …
Matched Categories: … Indicators and Reagents ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Technetium Tc-99m red blood cells

Technetium Tc-99m red blood cells is a radiopharmaceutical diagnostic agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. It is clinically useful in early detection and localization of bleeding sites, and...
Approved
Matched Description: … Autologous red blood cells are radiolabeled with sodium pertechnetate Tc 99m in the reaction vial. ... It is clinically useful in early detection and localization of bleeding sites, and preoperative diagnosis ... gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. …

Protein S human

Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties . It serves as a negative feedback mechanism in the coagulation cascade.
Approved
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Protein C

Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Description: … thrombosis and purpura fulminans. ... VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. ... its effect by inactivating essential components of the coagulation cascade (specifically factors V and …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Fluciclovine (18F)

Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the...
Approved
Matched Description: … [A31385] Fluciclovine was developed by Blue Earth Diagnostics, Ltd. and FDA approved in May 27, 2016. …

Mephenytoin

Mephenytoin is used for the treatment of refractory partial epilepsy. Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. Mephenytoin is known to target sodium channel protein type 5 subunit alpha. Cytochrome P450 2C19, Cytochrome...
Approved
Investigational
Withdrawn
Matched Description: … Mephenytoin is known to target sodium channel protein type 5 subunit alpha. ... Mephenytoin and oxazolidinedione derivatives are associated with higher incidences of blood dyscrasias ... Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2B6, Cytochrome P450 1A2, and …

Dipyrithione

Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff shampoo, but is no longer available. It is currently used as a pesticide, and not used in any FDA approved drug products. Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum antitumor activity, which...
Approved
Matched Description: … [A32825] Pyrithione derivatives, such as [DB06815] and sodium pyrithione, are widely used as cosmetic ... [A32829] Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum ... preservatives and as anti-dandruff agents in shampoos. …

Coagulation factor X human

Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Description: … children (aged 12 years and above) with hereditary Factor X deficiency. ... Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... the perioperative setting for the management of bleeding in major surgery in patients with moderate and …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Rifamycin

Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product of fermentation from the gram-positive bacterium Amycolatopsis mediterranei, also known as Streptomyces mediterranei. The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence...
Approved
Investigational
Matched Description: … Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] ... Some small modifications where performed in this inactive compound and with the creation of rifamycin ... ] Rifamycin has had several direct derivative products such as rifamycin SV, rifaximin, rifampin and …
Matched Salts name: … Rifamycin sodium …
Matched Categories: … Alimentary Tract and Metabolism …

Scopolamine

Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine.[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine...
Approved
Investigational
Matched Description: … nervous system and cholinergic signalling. ... vomiting associated with motion sickness and surgical procedures. ... available as both oral tablets and a transdermal delivery system. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Hypnotics and Sedatives ... Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Mydriatics and Cycloplegics …

Potassium hydroxide

Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved
Matched Description: … in electroplating, lithography, and paint and varnish removers. ... It is used in various chemical, industrial and manufacturing applications. ... Recently, it has been studied for efficacy and tolerability in the treatment of warts. …
Matched Categories: … Indicators and Reagents …

Diethylamino hydroxybenzoyl hexyl benzoate

Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated in the oil phase of...
Approved
Matched Description: … U.S., South America, Mexico, Japan and Taiwan. ... Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic ... Diethylamino hydroxybenzoyl hexyl benzoate was approved in Europe in 2005, and is also marketed in the …
Matched Mixtures name: … Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types ... Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types …

Apis mellifera venom

Apis mellifera venom is an extract of Apis mellifera venom. Apis mellifera venom is used in allergenic testing.
Approved
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Bee Venom Wart And Tags Removal Treatment …
Matched Categories: … Bee and Wasp Venom …

Nitrazepam

A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Approved
Matched Description: … A benzodiazepine derivative used as an anticonvulsant and hypnotic. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …

Lamotrigine

Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It...
Approved
Investigational
Matched Description: … It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. ... Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval ... [A191350] Lamotrigine has relatively few side-effects and does not require laboratory monitoring. …
Matched Categories: … Sodium Channel Blockers ... Calcium-Regulating Hormones and Agents …

Tocofersolan

D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of bile flow, either to impaired secretion by hepatocytes (liver cells) or obstruction , . Tocofersolan is a...
Approved
Matched Description: … Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version ... capable of demonstrating antioxidant effects that make it a popular component to include in cosmetics and …
Matched Categories: … Alimentary Tract and Metabolism …

Flecainide

Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056] Flecainide was granted FDA...
Approved
Withdrawn
Matched Description: … fibrillation and flutter. ... Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. ... [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate …
Matched Categories: … Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …

Lysine

Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as...
Approved
Nutraceutical
Matched Description: … Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. ... The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. ... posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and …
Matched Mixtures name: … Effervescent Potassium Chloride ... Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … arginine and lysine ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions …

Equus caballus skin

Equus caballus skin allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Horse Hair and Dander …

Oryctolagus cuniculus skin

Oryctolagus cuniculus skin or pelt is used in allergenic testing.
Approved
Matched Mixtures name: … Rabbit Hair and Epithelia …

Bromodiphenhydramine

Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.
Approved
Matched Mixtures name: … Diphenhydramine HCI and Zinc Acetate …

Canis lupus familiaris skin

Canis lupus familiaris skin allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Dog Hair and Epithelia …

Human adenovirus e serotype 4 strain cl-68578 antigen

Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine.
Approved
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …

Adenovirus type 7 vaccine live

Approved
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Displaying drugs 376 - 400 of 14523 in total