Displaying drugs 401 - 425 of 11931 in total
Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 5 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Description: … Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... capsular antigens of *Streptococcus pneumoniae* serotype 5 individually conjugated to the CRM197 protein, a …
Casein
Casein allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Description: … Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic ... Elbasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly. ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 …
Aclidinium
Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Approved
Matched Description: … It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. …
Methylprednisone
Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Approved
Investigational
Matched Iupac: … hydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Cetrorelix
Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational
Matched Description: … Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). …
Almotriptan
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Description: … Almotriptan is a triptan drug for the treatment of migraine headaches. ... Almotriptan is in a class of medications called selective serotonin receptor agonists. …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Categories: … Monoamine Oxidase A Substrates …
Pegaptanib
Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability.
Pegaptanib was granted FDA approval on 17 September 2004.
Approved
Investigational
Matched Description: … Pegaptanib is a polynucleotide aptamer. …
Matched Categories: … Vascular Endothelial Growth Factor A …
Matched Categories: … Vascular Endothelial Growth Factor A …
Perflubutane
Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress testing; currently the leading procedure for detecting coronary heart disease.
Approved
Investigational
Matched Description: … It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Zidovudine
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Description: … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during ... A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced …
Matched Mixtures name: … N/A …
Matched Mixtures name: … N/A …
Indocyanine green
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Olanzapine
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched International brands: … CO Olanzapine …
Matched Description: … Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent ... very closely resembles [clozapine] and only differs by two additional methyl groups and the absence of a …
Matched Description: … Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent ... very closely resembles [clozapine] and only differs by two additional methyl groups and the absence of a …
Cholestyramine
Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Description: … Cholestyramine or colestyramine is a bile acid sequestrant. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Creatine
An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Sucrose
A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Approved
Experimental
Investigational
Matched Description: … food and a sweetener. ... A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. ... obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Gadobutrol
Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is
formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Description: … Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast ... fibrosis (NSF) due to the dissociation of gadolinium from the chelates, although gadobutrol tends to have a ... gadobutrol is
formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Technetium Tc-99m pertechnetate
Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … a similar extent as iodine. ... This is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby ... Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Polyethylene glycol 400
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … a low-level toxicity. ... In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788 ... [L1787]
Polyethylene glycol 400 (PEG 400) is a low-molecular-weight grade of polyethylene glycol with …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Echinacea purpurea flowering top
Approved
Experimental
Ambenonium
Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis.
Approved
Matched Description: … Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis. …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Description: … Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. ... a post-market clinical study (the CARES trial) where there was an increased risk of cardiovascular ( ... [A230548]
In February 2019, a black box warning for febuxostat was added, based on the findings of …
Macimorelin
Macimorelin, a novel and orally active ghrelin mimetic that stimulates GH secretion, is used in the diagnosis of adult GH deficiency (AGHD). More specifically, macimorelin is a peptidomimetic growth hormone secretagogue (GHS) that acts as an agonist of GH secretagogue receptor, or ghrelin receptor (GHS-R1a) to dose-dependently increase GH levels...
Approved
Investigational
Matched Description: … More specifically, macimorelin is a peptidomimetic growth hormone secretagogue (GHS) that acts as an ... Macimorelin, a novel and orally active ghrelin mimetic that stimulates GH secretion, is used in the diagnosis ... Risk factors of AGHD include a history of childhood-onset GH deficiency or with hypothalamic/pituitary …
Bulevirtide
Hepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development of cirrhosis, severe decompensation of liver function, and an increased risk of mortality.[A226340,L30235] Until recently, there have been extremely limited treatments available for Hepatitis D infection. Bulevirtide, also known as Hepcludex, is a...
Approved
Investigational
Matched Description: … [A226305]
Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment …
Alogliptin
Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase ... Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Displaying drugs 401 - 425 of 11931 in total