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Displaying drugs 4276 - 4300 of 11495 in total

TAK-475

TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been brought to market.
Investigational
Matched Description: … TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been …

Calcium

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
Matched Description: … The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. ... Low calcium intake may also be a risk factor in the development of osteoporosis. ... Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, …
Matched Mixtures name: … One A Day Tab ... Calcium A D ... A-D Calcium Cap …
Matched Products: … ENA Actimineral A …

Anvatabart opadotin

Investigational
Matched Synonyms: … 2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody; conjugated at two engineered sites via a …

Nemvaleukin alfa

Investigational
Matched Synonyms: … Fusion protein comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain …

LB-001

LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA mutase (MUT) gene into the genome of patients with methylmalonic acidemia.
Investigational
Matched Description: … LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA …

MK-8245

MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus.
Investigational
Matched Categories: … Stearoyl-CoA Desaturase, antagonists & inhibitors …

Amino acids

Mixture of amino acids ; used for parenteral nutrition in infants.
Investigational
Matched Products: … AMINOACIDI A CATENA RAMIFICATA ... AMINOACIDI A CATENA RAMIFICATA MONICO …

Coagulation factor XIa

Coagulation factor XIa is under investigation in clinical trial NCT01701947 (HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency).
Investigational

mRNA-3705

mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. Developed by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.
Investigational
Matched Description: … mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. …

Meglutol

An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Experimental
Matched Description: … as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting ... interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A …

Emivirine

Emivirine has been used in trials studying the treatment of HIV Infections.
Investigational

Dorsomorphin

Experimental
Matched Iupac: … 4-(6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}pyrazolo[1,5-a]pyrimidin-3-yl)pyridine …

MK-8776

Sch 900776 has been used in trials studying the treatment of Neoplasms, Hodgkin Disease, Adult Erythroleukemia, Lymphoma, Non-Hodgkin, and Myelogenous Leukemia, Acute, among others.
Investigational
Matched Iupac: … 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine …

Giroctocogene fitelparvovec

Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).
Investigational
Matched Description: … (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a …

mRNA-3927

mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Matched Description: … carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). ... consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA …

Mevastatin

Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Description: … Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 ... times greater than the HMG-CoA substrate itself. ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …

Batroxobin

Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox moojeni. In addition to batroxobin, the venom of Bothrops atrox has a composition of 10.2% neutral carbohydrate. Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. The...
Experimental
Matched Description: … Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox ... Batroxobin will also bind fibrinogen in a manner different than thrombin and with a higher affinity. ... Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. …
Matched Categories: … Venombin A …

Nafamostat

Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome. The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing...
Investigational
Matched Description: … Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid …

Amdinocillin

Amidinopenicillanic acid derivative with broad spectrum antibacterial action. It is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Investigational
Withdrawn

Ocinaplon

Investigational
Matched Iupac: … 4-[3-(pyridine-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine …

Dinaciclib

Dinaciclib has been used in trials studying the treatment of rrMM, rrCLL, rrDLBCL, Solid Tumors, and Solid Neoplasm, among others.
Investigational
Matched Iupac: … 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]pyridin …

5-methyltetrahydrofolic acid

5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine synthases).
Investigational
Nutraceutical
Matched International brands: … Prefolic A …
Matched Description: … 5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. …

TTX-MC138

TTX-MC138 is an antisense oligonucleotide targeting miR-10b. It is under investigation for the treatment of various metastatic cancers.
Investigational

Sennosides

Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label] and empty the large intestine before surgery. The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given...
Experimental
Matched Description: … It is a weaker laxative than bisacodyl or castor oil[A177092]. ... Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label ... Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective …
Matched Salts name: … Sennosides A and B …

NeuroCell-PD

Investigational
Displaying drugs 4276 - 4300 of 11495 in total