Displaying drugs 4326 - 4350 of 5555 in total
CP-724714
CP-724,714 has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasm Metastasis.
Investigational
Matched Iupac: … 2-methoxy-N-[(2E)-3-[4-({3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl}amino)quinazolin-6-yl]prop-2-en …
Bucladesine
Experimental
Matched Iupac: … (4aR,6R,7R,7aR)-6-(6-butanamido-9H-purin-9-yl)-2-hydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin …
INCB-057643
INCB-057643 is under investigation in clinical trial NCT02959437 (Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)).
Investigational
Matched Iupac: … 6-methanesulfonyl-2,2,4-trimethyl-8-{6-methyl-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-4-yl}-3,4-dihydro- …
Quinfamide
Quinfamide has been used in trials studying the treatment of Amoebiasis and Helminthiasis.
Investigational
Matched Iupac: … 1-(2,2-dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl furan-2-carboxylate …
Fenquizone
Experimental
Matched Iupac: … 7-chloro-4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Sulfamethoxypyridazine
Experimental
Matched Iupac: … 4-amino-N-(6-methoxypyridazin-3-yl)benzene-1-sulfonamide …
Snubh-nm-333 F-18
Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F)).
Investigational
Matched Iupac: … 4-[6-(¹⁸F)fluoro-1,3-benzothiazol-2-yl]-N-methylaniline …
Landipirdine
Landipirdine is under investigation in clinical trial NCT02258152 (SYN120 Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)).
Investigational
Matched Iupac: … {[(1R)-6-(3-fluorobenzenesulfonyl)-1,2,3,4-tetrahydronaphthalen-1-yl]methyl}urea …
Cerulenin
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
E7107
E7107 has been used in trials studying the treatment of Cancer.
Investigational
Matched Iupac: … ]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-1-oxacyclododec-4-en-6-yl 4-cycloheptylpiperazine ... (2S,3S,4E,6S,7R,10R)-7,10-dihydroxy-2-[(2E,4E,6R)-6-hydroxy-7-[(2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl …
Dodecyl-Alpha-D-Maltoside
Experimental
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6S)-6-(dodecyloxy)-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-6- …
2-Fluoro-2-Deoxy-Beta-D-Galactopyranosyl-Beta-D-Glucopyranose
Experimental
Matched Iupac: … (2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-3-fluoro-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl …
octyl 3-amino-3-deoxy-2-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-galactopyranoside
Experimental
Matched Iupac: … (2S,3S,4S,6S)-6-{[(2R,3R,4S,5R,6R)-4-amino-5-hydroxy-6-(hydroxymethyl)-2-(octyloxy)oxan-3-yl]oxy}-2-methyloxane …
BMS-986141
BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).
Investigational
Matched Iupac: … 4-(4-{[(6-methoxy-2-{2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl}-1-benzofuran-4-yl)oxy]methyl}-1,3 …
Florzolotau F-18
PMPBB3 F-18 is under investigation in clinical trial NCT04305210 (Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18f-florbetapir (AV-45) PET Examination).
Investigational
Matched Iupac: … 1-(¹⁸F)fluoro-3-({2-[(1E,3E)-4-[6-(methylamino)pyridin-3-yl]buta-1,3-dien-1-yl]-1,3-benzothiazol-6-yl …
2',4'-Dinitrophenyl-2deoxy-2-Fluro-B-D-Cellobioside
Experimental
Matched Iupac: … -3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... (2S,3R,4S,5S,6R)-2-{[(2R,3S,4S,5R,6S)-6-(2,4-dinitrophenoxy)-5-fluoro-4-hydroxy-2-(hydroxymethyl)oxan …
AMG-337
AMG-337 is under investigation in clinical trial NCT03147976 (QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors).
Investigational
Matched Iupac: … 6-[(1R)-1-[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy …
Nz-(1-Carboxyethyl)-Lysine
Experimental
Matched Iupac: … (2S)-2-amino-6-{[(1R)-1-carboxyethyl]amino}hexanoic acid …
Beta-D-Glucose
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Experimental
Matched Iupac: … (2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol …
4-O-Demethylpenclomedine
Investigational
Matched Iupac: … 3,5-dichloro-2-methoxy-6-(trichloromethyl)-1,4-dihydropyridin-4-one …
Cadralazine
Experimental
Matched Iupac: … N'-{6-[ethyl(2-hydroxypropyl)amino]pyridazin-3-yl}ethoxycarbohydrazide …
Flutemetamol
Flutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).
Investigational
Matched Iupac: … 2-[3-fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol …
Sepiapterin
Sepiapterin is under investigation in clinical trial NCT03519711 (A Study of CNSA-001 in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalaninemia).
Investigational
Matched Iupac: … 2-amino-6-[(2S)-2-hydroxypropanoyl]-1,4,7,8-tetrahydropteridin-4-one …
Reproxalap
Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis, and Sjögren-Larsson syndrome. NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome.
Investigational
Matched Iupac: … 2-(3-amino-6-chloroquinolin-2-yl)propan-2-ol …
Displaying drugs 4326 - 4350 of 5555 in total