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Displaying drugs 426 - 450 of 3214 in total
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. ... Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Withdrawn
Matched Synonyms: … Tienilic acid ... Thienylic acid ... Acide tiénilique …
Matched Name: … Tienilic acid
Matched Iupac: … 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid
Matched Description: … It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and ... Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Hydroxy Acids ... tienilic acid ... Aryloxyacetic Acid Derivatives …
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Acid-alpha glucosidase ... Human acid precursor alpha-glucosidase, recombinant ... Acid maltase …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Approved
Experimental
Matched Synonyms: … Acide stéarique ... Stearic acid ... Acide octadécanoïque …
Matched Name: … Stearic acid
Matched Iupac: … octadecanoic acid
Matched Description: … acids that comes from many animal and vegetable fats and oils. ... Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty …
Matched Categories: … Fatty Acids ... Stearic Acids
Investigational
Matched Synonyms: … .ALPHA.-1-ACID GLYCOPROTEIN ... ALPHA-1-ACID GLYCOPROTEIN 1 ... ALPHA-1-ACID GLYCOPROTEIN-1 …
Matched Name: … Alpha-1-acid glycoprotein …
Experimental
Matched Synonyms: … Glutamic acid alpha-amide ... L-Glutamic acid alpha-amide ... L-alpha-Glutamine …
Matched Iupac: … (4S)-4-amino-4-carbamoylbutanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …
Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Investigational
Matched Synonyms: … STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and
Matched Description: … primate STEAP1 and CD3. ... Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman …
Approved
Vet approved
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid …
Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs...
Approved
Matched Synonyms: … 4-(butylamino)benzoic acid 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester ... nonaethyleneglycol monomethyl ether p-n-butylaminobenzoate ... p-butylaminobenzoic acid ω-O-methylnonaethyleneglycol ester …
Matched Description: … acid class (such as [procaine] and [tetracaine]), benzonatate exhibits anesthetic or numbing action. ... Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... Benzonatate was approved by the FDA in 1958 under the market name Tessalon Perles. …
Matched Categories: … Cough and Cold Preparations …
A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Approved
Investigational
Matched Synonyms: … alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester ... 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester ... alpha-p-Chlorophenoxyisobutyryl ethyl ester …
Matched Iupac: … ethyl 2-(4-chlorophenoxy)-2-methylpropanoate …
Matched Description: … A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia …
Matched Categories: … Ethers ... Phenyl Ethers ... Acids, Acyclic ... Clofibric Acid ... Carboxylic Acids
Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. ... Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions. ... Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and
Matched Categories: … Antiseptics and Disinfectants ... Acids ... Acids, Noncarboxylic …
Matched Products: … SUPERCLEAN Micro Acid Hypochlorite Disinfectant …
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid
Matched Description: … glypromate], also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … alpha-Tocopheryl acid succinate ... d-alpha-Tocopherol acid succinate ... Tocopheryl acid succinate,D-alpha
Matched Name: … alpha-Tocopherol succinate …
Matched Iupac: … 2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl]oxy}butanoic acid
Matched Description: … [A32958] activities that are unique from the alpha-tocopherol form and other alpha-tocopherol esters ... is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability ... , making a compound such as alpha-tocopherol succinate more stable and easier to use in vitamin supplements …
Matched Mixtures name: … Folic Acid Plus ... Multi-Vitamin Fluoride and Iron Drops ... Co-q10 and Vitamin E …
Matched Categories: … Diet, Food, and Nutrition …
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Description: … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against ... [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused ... by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose …
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Description: … Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ... cisplatin, and has reported anxiolytic and neuroleptic properties. ... [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more …
Matched Categories: … Antiemetics and Antinauseants …
Matched Products: … Ondansetron and Dextrose ... Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose …
Experimental
Matched Synonyms: … Nitrous acid, ethyl ester ... Nitrous ether spirit ... Spirit of ethyl nitrite …
Matched Name: … Ethyl nitrite …
Matched Iupac: … ethyl nitrite …
Investigational
Matched Synonyms: … Benzoic acid, 2-((2-chloro-4-iodophenyl)amino)-3,4-difluoro- …
Matched Iupac: … 2-[(2-chloro-4-iodophenyl)amino]-3,4-difluorobenzoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist.
Experimental
Matched Synonyms: … (E)-4-(2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl)benzoic acid ... Arotinoic acid ... Arotinoid acid
Matched Name: … Arotinoid acid
Matched Iupac: … 4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid
Matched Description: … Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … alpha-Aminoisobutyric acid ... alpha-Methylalanine ... 2-aminoisobutyric acid
Matched Name: … 2-aminoisobutyric acid
Matched Iupac: … 2-amino-2-methylpropanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids ... Amino Acids, Branched-Chain …
alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study).
Investigational
Matched Synonyms: … .ALPHA.-HYDROXYLINOLEIC ACID ... (9Z,12Z)-2-HYDROXY-9,12-OCTADECADIENOIC ACID ... 9,12-OCTADECADIENOIC ACID, 2-HYDROXY-, (9Z,12Z)- …
Matched Name: … alpha-Hydroxylinoleic acid
Matched Iupac: … (9Z,12Z)-2-hydroxyoctadeca-9,12-dienoic acid
Matched Description: … alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … [(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid ... {(1S,2R)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3aS …
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] ... [A2278,A2281] It was initially approved by the FDA in 2006. …
Matched Categories: … Carboxylic Acids ... darunavir and ritonavir ... darunavir and cobicistat ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Darunavir 600 and 800 mg …
D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of bile flow, either to impaired secretion by hepatocytes (liver cells) or obstruction , . Tocofersolan is a...
Approved
Matched Synonyms: … (+)-.ALPHA.-TOCOPHERYL POLYETHYLENE GLYCOL 1000 SUCCINATE ... D-.ALPHA.-TOCOPHEROL POLYETHYLENE GLYCOL 1000 SUCCINATE ... VITAMIN E POLYETHYLENE GLYCOL SUCCINATE …
Matched Description: … Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version ... D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe ... capable of demonstrating antioxidant effects that make it a popular component to include in cosmetics and
Matched Categories: … Alimentary Tract and Metabolism …
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched International brands: … Nal-acid
Matched Synonyms: … 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid ... 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid ... 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
Matched Name: … Nalidixic acid
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Categories: … nalidixic acid
Matched Products: … ACIDO NALIDIXICO ... ACIDO NALIDIXICO NOVASOREL ... ACIDO NALIDIXICO SUSPENSION …
Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid
Matched Iupac: … (3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic acid
Experimental
Matched Synonyms: … Pipemidic acid ... acido pipemidico …
Matched Name: … Pipemidic acid
Matched Iupac: … 8-ethyl-5-oxo-2-(piperazin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid
Matched Salts name: … Pipemidic acid trihydrate …
Matched Categories: … Acids, Heterocyclic ... Nicotinic Acids ... pipemidic acid
Matched Products: … ACIDO PIPEMIDICO EG ... ACIDO PIPEMIDICO AUROBINDO ... ACIDO PIPEMIDICO DR. REDDY'S …
Displaying drugs 426 - 450 of 3214 in total