Displaying drugs 426 - 450 of 2733 in total
Clonazepam
A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop.[FDA Label][L5572,F3763,F3787,F3796] The agent has also been indicated for treating panic disorder.[FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.[FDA Label][A175438,A175441,L5572,F3763,F3787,F3796]
Since being...
Approved
Illicit
Atoltivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Description: … Ebola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible …
Maftivimab
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Description: … Ebola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible …
Vinorelbine
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC .
It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Estradiol valerate
Estradiol Valerate (also known as E2V) is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore...
Approved
Investigational
Vet approved
Matched Description: … pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human ... exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human …
Kappadione
Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is not available in North America . It has been found to have carcinogenic potential in mammalian cells as...
Approved
Gallium Ga-68 gozetotide
Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Description: … In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended Ga-68 gozetotide …
Amitriptyline
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Carbon monoxide
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought...
Approved
Investigational
Matched Description: … a ubiquitous environmental product of organic combustion, which is also formed endogenously in the human …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Fluticasone
Fluticasone is a synthetic glucocorticoid available as 2 esters, DB08906 and DB00588[F4355,F4358,F4361,F4364][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358,F4361,F4364][FDA Label]. DB00588 was first approved in 1990 and DB08906 was approved in 2007 .
Approved
Experimental
Imatinib
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Moxonidine
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Haloperidol
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Description: … However, these findings contradict the findings from studies in vitro with human liver microsomes and …
Clobazam
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Methadone
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Hyaluronidase (human recombinant)
A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Synonyms: … Hyaluronidase human recombinant ... Hyaluronidase (human recombinant) ... Hyaluronidase recombinant human …
Matched Name: … Hyaluronidase (human recombinant) …
Matched Description: … A purified preparation of the enzyme recombinant human hyaluronidase. ... Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese ... Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase …
Matched Products: … HYLENEX Recombinant ... HYLENEX Recombinant Professional Sample …
Matched Name: … Hyaluronidase (human recombinant) …
Matched Description: … A purified preparation of the enzyme recombinant human hyaluronidase. ... Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese ... Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase …
Matched Products: … HYLENEX Recombinant ... HYLENEX Recombinant Professional Sample …
Insulin human
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Synonyms: … Insulin recombinant human ... Insulin recombinant purified human ... Human insulin …
Matched Name: … Insulin human …
Matched Description: … Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the ... human insulin gene into Escherichia coli bacteria or Saccharomyces cerevisiae. …
Matched Mixtures name: … Humulin 30/70 (insulin Human Biosynth Inj) ... Humulin 30/70 (insulin Human Biosynth Inj) …
Matched Salts name: … Insulin human zinc suspension …
Matched Categories: … insulin (human) ... insulin (human) ... insulin (human) ... insulin (human) ... insulin (human) …
Matched Products: … Insulin Human Winthrop Rapid ... Insulin Human Winthrop Basal ... Insulin Human Winthrop Comb 15 …
Matched Name: … Insulin human …
Matched Description: … Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the ... human insulin gene into Escherichia coli bacteria or Saccharomyces cerevisiae. …
Matched Mixtures name: … Humulin 30/70 (insulin Human Biosynth Inj) ... Humulin 30/70 (insulin Human Biosynth Inj) …
Matched Salts name: … Insulin human zinc suspension …
Matched Categories: … insulin (human) ... insulin (human) ... insulin (human) ... insulin (human) ... insulin (human) …
Matched Products: … Insulin Human Winthrop Rapid ... Insulin Human Winthrop Basal ... Insulin Human Winthrop Comb 15 …
Janssen COVID-19 Vaccine
The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharmaceutical, and the Beth Israel Deaconess Medical Center. A preclinical study in hamsters infected with...
Approved
Investigational
Matched Synonyms: … AD26.COV2.S [RECOMBINANT] …
Matched Name: … Janssen COVID-19 Vaccine …
Matched Description: … The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype ... The Janssen COVID-19 vaccine is available under an Emergency Use Authorization (EUA) in the US. …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Janssen COVID-19 Vaccine ... Covid-19 Vaccine Janssen …
Matched Name: … Janssen COVID-19 Vaccine …
Matched Description: … The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype ... The Janssen COVID-19 vaccine is available under an Emergency Use Authorization (EUA) in the US. …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Janssen COVID-19 Vaccine ... Covid-19 Vaccine Janssen …
Secretin human
Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Synonyms: … Human secretin ... Secretin human ... Secretin (human) …
Matched Name: … Secretin human …
Matched Description: … Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas ... Purified synthetic human secretin, also referred to as RG1068, is available as an intravenous injection ... Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Name: … Secretin human …
Matched Description: … Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas ... Purified synthetic human secretin, also referred to as RG1068, is available as an intravenous injection ... Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring …
Matched Salts name: … Secretin human pentahydrochloride …
Antihemophilic factor, human recombinant
Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Synonyms: … Human factor VIII recombinant ... Human Factor VIII (Recombinant) ... Antihemophilic factor, human recombinant …
Matched Name: … Antihemophilic factor, human recombinant …
Matched Description: … Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by …
Matched Categories: … Human Antihemophilic Factors …
Matched Name: … Antihemophilic factor, human recombinant …
Matched Description: … Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by …
Matched Categories: … Human Antihemophilic Factors …
Antihemophilic factor (recombinant), PEGylated
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label].
Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Synonyms: … Antihemophilic Factor (Recombinant), PEGylated ... antihemophilic factor (recombinant), PEGylated-aucl …
Matched Name: … Antihemophilic factor (recombinant), PEGylated …
Matched Description: … Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor ... Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product …
Matched Categories: … Recombinant Proteins ... Human Antihemophilic Factors …
Matched Name: … Antihemophilic factor (recombinant), PEGylated …
Matched Description: … Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor ... Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product …
Matched Categories: … Recombinant Proteins ... Human Antihemophilic Factors …
Antihemophilic factor human
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … F8 protein, human ... factor VIII, human ... Factor VIII (human) …
Matched Name: … Antihemophilic factor human …
Matched Description: … plasma, rather than being produced through recombinant DNA technology. ... a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential ... ], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced …
Matched Mixtures name: … von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... Wilate - von Willebrand Factor/Coagulation Factor VIII Complex (Human) …
Matched Categories: … Human Antihemophilic Factors …
Matched Name: … Antihemophilic factor human …
Matched Description: … plasma, rather than being produced through recombinant DNA technology. ... a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential ... ], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced …
Matched Mixtures name: … von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... Wilate - von Willebrand Factor/Coagulation Factor VIII Complex (Human) …
Matched Categories: … Human Antihemophilic Factors …
Human albumin microspheres
Approved
Experimental
Matched Synonyms: … Albumin human, microspheres ... Albumin microsphere human serum ... Albumin, microsphere human serum …
Matched Name: … Human albumin microspheres …
Matched Name: … Human albumin microspheres …
Displaying drugs 426 - 450 of 2733 in total