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Displaying drugs 4676 - 4700 of 10637 in total
PKI-179
PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors.
Investigational
Matched Description: … PKI-179 has been used in trials studying the treatment of Advanced Malignant Solid Tumors. …
Tribenoside
Anti-inflammatory agent used in edema of extremities, varicose veins & phlebitis.
Experimental
Matched Description: … Anti-inflammatory agent used in edema of extremities, varicose veins & phlebitis. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Chlorphentermine
A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223)
Illicit
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Matched Description: … It has properties similar to those of dextroamphetamine. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Benmoxin
Benmoxin is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class. It was first synthesized in 1967 and rapidly used in Europe as an antidepressant. However, this agent is no longer marketed.
Withdrawn
Matched Description: … Benmoxin is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Mebanazine
Mebanazine, also known as Actomol, is a monoamine oxidase inhibitor (MAOI) belonging to the hydrazine class of chemicals. It was used in the past as an antidepressant in the 1960s, but has since been discontinued because of its hepatotoxic potential.
Withdrawn
Matched Description: … also known as _Actomol_, is a monoamine oxidase inhibitor (MAOI) belonging to the _hydrazine_ class of ... It was used in the past as an antidepressant in the 1960s, but has since been discontinued because of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Pheniprazine
Pheniprazine is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant in the 1960s. In addition, it was used for the treatment of other conditions, such as angina pectoris and schizophrenia. Pheniprazine was withdrawn by its manufacturer due to its...
Withdrawn
Matched Description: … Pheniprazine is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine ... In addition, it was used for the treatment of other conditions, such as angina pectoris and schizophrenia …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Methylestrenolone
Experimental
Matched Categories: … Sex Hormones and Modulators of the Genital System …
N,N-dimethylarginine
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a...
Experimental
Matched Description: … It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human ... ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and …
YKP-1358
YKP1358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that has demonstrated potent activity in animals that relates to both positive and negative symptoms of schizophrenia. In addition, the YKP1358 pharmacological profile suggests a very low potential for extrapyramidal side effects.
Investigational
Matched Description: … that has demonstrated potent activity in animals that relates to both positive and negative symptoms of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Pivhydrazine
Pivhydrazine, also known as pivazide, is a member of the hydrazine family with irreversible and non-selective inhibitory activity against monoamine oxidases. In 1960, it was widely used as an antidepressant agent but it is now discontinued.
Withdrawn
Matched Description: … Pivhydrazine, also known as pivazide, is a member of the hydrazine family with irreversible and non-selective …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Rauwolfia serpentina root
Rauwolfia (Rauwolfia serpentina), also spelled ravolphia, is a medicinal plant in the milkweed family. The root of the plant is ground into a powder or sold in tablets or capsules. It is a compound commonly used in Asian medicine, which includes traditional Ayurvedic medicine native to India. The active ingredients...
Investigational
Matched Description: … The root of the plant is ground into a powder or sold in tablets or capsules. ... For this reason, various studies into biotechnological applications of this plant have been performed ... on their biosynthetic potential and numerous biotechnological methods used to study the production of …
Matched Categories: … combinations of rauwolfia alkaloids …
Matched Categories: … combinations of rauwolfia alkaloids …
2,5-Dimethoxy-4-ethylthioamphetamine
2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties.
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
LU-31130
LU-31130 is a rapid acting therapy developed by H. Lundbeck A/S to treat Psychosis, Schizophrenia and Schizoaffective Disorders. It acts at the Dopamine D4 receptors in the cortex and has low affinity for D2 receptors, adrenoceptors, muscarinic and histaminergic receptors.
It provides anti-psychotic characteristic and a low incidence of extrapyramidal...
Investigational
Matched Description: … Lundbeck A/S to treat Psychosis, Schizophrenia and Schizoaffective Disorders. ... It provides anti-psychotic characteristic and a low incidence of extrapyramidal and cardiovascular side …
Biricodar
The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).
Investigational
Matched Description: … The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein …
Eltoprazine
Eltoprazine has been used in trials studying the treatment of Schizophrenia and Cognitive Impairment.
Investigational
Matched Description: … Eltoprazine has been used in trials studying the treatment of Schizophrenia and Cognitive Impairment. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Fluoroazomycin arabinoside F-18
Fluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer).
Investigational
Matched Description: … Use of Irreversible Electroporation in Pancreatic Ductal Cancer). ... Fluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Categories: … Diagnostic Uses of Chemicals …
INO-4800
INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.[A214475, A214478] Follow up studies in both...
Investigational
Matched Description: … results in the expression of S protein by human cells. ... INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development ... Furthermore, the antibodies produced were capable of inhibiting the binding of SARS-CoV-2 to the ACE2 …
Etretinate
Etretinate is a medication used to treat severe psoriasis. It is a synthetic aromatic retinoid. The mechanism of action of etretinate is still incompletely understood although, like retinoic acid, it is thought to interfere with the terminal differentiation of keratinocytes. It is thought to bind to the retinoic acid receptors....
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Matched Description: … The mechanism of action of etretinate is still incompletely understood although, like retinoic acid, ... Etretinate is also believed to enhance the binding of cAMP to the regulatory RI subunit of cAMP dependent ... it is thought to interfere with the terminal differentiation of keratinocytes. …
Matched Categories: … Retinoids for Treatment of Psoriasis …
Matched Categories: … Retinoids for Treatment of Psoriasis …
Displaying drugs 4676 - 4700 of 10637 in total