Displaying drugs 451 - 475 of 780 in total
Cemiplimab
Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1), which is a negative regulator of T cell function. By blocking PD-1, cemiplimab works to enhance T cell-mediated antitumour responses. Cemiplimab was first approved by the FDA on September 28, 2018, as the first FDA-approved treatment...
Approved
Investigational
Teplizumab
Teplizumab (teplizumab-mzwv) is a humanized IgG1 kappa CD3-directed monoclonal antibody used to delay the onset of type 1 diabetes (T1D).[A241480,A241045,A241475,L44091] T1D is an autoimmune condition in which T cell-mediated destruction of pancreatic β cells leads to loss of insulin production, impaired glycemic control, and reliance on exogenous insulin. Anti-CD3 therapy...
Approved
Investigational
Matched Description: … [L44091] Fc-receptors can bind to the "tail-end" anti-CD3 antibodies in an antigen-non-specific manner …
Flumethasone
Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Approved
Vet approved
Matched Iupac: … (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Besilesomab
Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like...
Approved
Interferon alfacon-1
Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding position. Four additional amino acid changes were made to facilitate the...
Approved
Investigational
Trilaciclib
Trilaciclib, or G1T28, is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing chemotherapy for extensive stage small cell lung cancer. CDK4 and CDK6 inhibitors have been investigated since the mid 1990s for their use in tumorigenesis...
Approved
Investigational
Matched Iupac: … 12'-{[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino}-2',5',11',13'-tetraazaspiro[cyclohexane-1,3'-tricyclo …
Matched Categories: … MATE 2 Inhibitors ... MATE 2-K Inhibitors …
Matched Categories: … MATE 2 Inhibitors ... MATE 2-K Inhibitors …
Influenza B virus B/Massachusetts/2/2012 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Massachusetts/2/2012 live (attenuated) antigen …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Cat dander extract
Cat dander extract is either subcutaneously or intracutaneously administered and contains dry cat dander or dry defatted cat pelt. It is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats. An allergic reaction to cats is induced by the presence of antigen-specific IgE...
Approved
Matched Description: … An allergic reaction to cats is induced by the presence of antigen-specific IgE antibodies that are bound …
Nogapendekin alfa
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Acalabrutinib
To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others.
As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, capsules). This Bruton tyrosine kinase (BTK) inhibitor indicated for the treatment of chronic...
Approved
Investigational
Matched Iupac: … 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide …
Moxetumomab pasudotox
CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 which specifically binds to CD22. This antibody was used to...
Approved
Investigational
Matched Description: … CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia …
Galactose
Galactose has been used in trials studying the treatment and diagnosis of Hepatitis C, Hepatic Cancer, Wilsons Disease, Diabetic Macular Oedema, and Focal Segmental Glomerulosclerosis, among others. There are even proposals for its use in accelerating senescence in mice, rats, and Drosophila, for its association with ovarian cancer, or even...
Approved
Investigational
Imlifidase
Chronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant burden for both the individual and healthcare system at large. Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life.[A225836,A225916]...
Approved
Investigational
Matched Description: … [A225836,A225916]
Patients who have developed human leukocyte antigen (HLA) sensitization from prior …
Antihemophilic factor human
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) …
Matched Mixtures name: … BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI …
Matched Mixtures name: … BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI …
Human adenovirus e serotype 4 strain cl-68578 antigen
Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine.
Approved
Matched Name: … Human adenovirus e serotype 4 strain cl-68578 antigen …
Matched Description: … Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine. …
Matched Description: … Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine. …
Hepatitis A Vaccine
Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely...
Approved
Matched Synonyms: … Hepatitis A vaccine, inactivated …
Matched Description: … [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently …
Matched Salts name: … Hepatitis A virus strain CR 326F antigen (formaldehyde inactivated) ... Hepatitis A virus strain HM175 antigen (formaldehyde inactivated) …
Matched Categories: … Inactivated Hepatitis A Virus Vaccine …
Matched Description: … [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently …
Matched Salts name: … Hepatitis A virus strain CR 326F antigen (formaldehyde inactivated) ... Hepatitis A virus strain HM175 antigen (formaldehyde inactivated) …
Matched Categories: … Inactivated Hepatitis A Virus Vaccine …
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 11A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … diphtheriae* strain C7 (β197). ... Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium …
Matched Categories: … Inactivated Pneumococcal Vaccine …
Matched Description: … diphtheriae* strain C7 (β197). ... Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium …
Matched Categories: … Inactivated Pneumococcal Vaccine …
Influenza B virus B/Colorado/06/2017 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Colorado/06/2017 live (attenuated) antigen …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Influenza A virus A/Brisbane/10/2010 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Brisbane/10/2010 live (attenuated) antigen …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Meningococcal polysaccharide vaccine group W-135
Meningococcal group W-135 polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup W-135. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup W-135.
Approved
Experimental
Investigational
Matched Synonyms: … Meningococcal polysaccharide antigen group W-135 ... Neisseria meningitidis group W-135 polysaccharide antigen, A ... neisseria meningitidis group W-135 capsular polysaccharide antigen …
Matched Categories: … Inactivated Meningococcal Vaccine …
Matched Categories: … Inactivated Meningococcal Vaccine …
Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen
Approved
Investigational
Matched Name: … Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen …
Meningococcal polysaccharide vaccine group A
Meningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup A. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup A.
Approved
Experimental
Investigational
Matched Synonyms: … Meningococcal polysaccharide antigen group A ... Neisseria meningitidis group A polysaccharide antigen, A ... Neisseria meningitidis group A capsular polysaccharide antigen …
Matched Categories: … Inactivated Meningococcal Vaccine …
Matched Categories: … Inactivated Meningococcal Vaccine …
Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen
Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated...
Approved
Matched Name: … Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen …
Matched Description: … Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine …
Matched Description: … Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine …
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Matched Categories: … Inactivated Meningococcal Vaccine …
Matched Description: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Matched Categories: … Inactivated Meningococcal Vaccine …
Displaying drugs 451 - 475 of 780 in total