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Displaying drugs 26 - 50 of 11667 in total
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ... {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid …
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid …
Matched Description: … indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2- …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Indocid retard 75 mg Kapseln ... INDO - CT 75 MG RETARDKAPS ... INOMET SR 75 MG MİKROPELLET KAPSÜL, 10 ADET …
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Synonyms: … 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole …
Matched Iupac: … 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine …
Matched Description: … Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Products: … TIZAN 2 ... โทโนไลท์ 2 ... ทีดาร์ 2 มก. …
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved...
Approved
Matched International brands: … Cardura-2
Matched Synonyms: … 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin ... 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin …
Matched Iupac: … 2-[4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … TENSIDOX-2 ... เพนคอร์ 2 ... ซาโดซิน 2
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Synonyms: … (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol …
Matched Iupac: … 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol …
Matched Products: … TEROTOL® 2 MG ... DETRUSITOL TABLET 2 mg ... DETRUSITOL SR (CAPSULE 2 MG) …
Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations. However, the development of KRAS inhibitors has been challenging due to their high affinity for guanosine triphosphate (GTP) and guanosine diphosphate...
Approved
Investigational
Matched Synonyms: … 2-piperazineacetonitrile, 4-(7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(((2s)-1-methyl-2-pyrrolidinyl ... (3,4-d)pyrimidin-4-yl)-1-(2-fluoroprop2-enoyl)piperazin-2-yl)acetonitrile ... )methoxy)pyrido(3,4-d)pyrimidin-4-yl)-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2s)- …
Matched Iupac: … -d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile ... 2-[(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H,6H,7H,8H-pyrido[3,4 …
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium ... -1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate …
Matched Iupac: … 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia ... -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Maxipime 2 g - Trockenstechampullen ... ROXIPIME 2 G IV ENJEKSIYON VE INFÜZYON IÇIN TOZ IÇEREN FLAKON ,1 ADET ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 g/vial …
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Synonyms: … 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline …
Matched Iupac: … 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine …
Matched Description: … ] or [apraclonidine], which are also alpha-2 adrenergic agonists. ... preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. ... Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in …
Matched Mixtures name: … Combigan 2 mg/ml + 5 mg/ml Augentropfen ... SIMBRINZA EYE DROPS, SUSPENSION 10 MG/ML + 2 MG/ML ... BRİMO-TİM 2 MG+5 MG/ML STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … BRIMOGEN 2 mg/ml Augentropfen, Lösung ... Brimonidin Arcana 2 mg/ml - Augentropfen ... BRIMONIDINA TARTRATO GOTAS OFTALMICAS 2 MG/ML (0.2%) …
An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Synonyms: … 1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinone …
Matched Iupac: … 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-dihydroanthracene-9,10-dione …
Matched Products: … MITOXANTRONE BAXTER INJECTION 2 mg/ml ... Ebexantron 2 mg/ml - Konzentrat zur Herstellung einer Infusionslösung ... Mitoxantron Accord 2 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Approved
Vet approved
Matched Synonyms: … 2-Dimethylaminoethoxyphenylmethyl-2-picoline ... 2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine ... N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine …
Matched Iupac: … dimethyl({2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethyl})amine …
Matched Mixtures name: … Tylenol Cold Plus Flu Severe Day and Tylenol Cold Plus Flu Plus Cough Night 2-pack …
Matched Products: … Unisom-2 Tablets …
Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Approved
Matched Synonyms: … 2-F-ARAA ... 2-fluoro ARA-A …
Matched Iupac: … (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … FLUMEN 50 MG/2 ML IV ENJEKTABL ÇÖZELTİ İÇEREN FLAKON ... FLUDALYM 50 MG/2 ML IV ENJEKSİYON/İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor...
Approved
Vet approved
Matched Synonyms: … 2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone ... 2-(methylamino)-2-(2-chlorophenyl)cyclohexanone ... 2-(o-chlorophenyl)-2-(methylamino)-cyclohexanone …
Matched Iupac: … 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one …
Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin.
Approved
Investigational
Matched Synonyms: … 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedione …
Matched Iupac: … 2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione …
Matched Products: … NITISOR® 2 MG ... NITISINONA 2 MG ... Nitisinon Dipharma 2 mg Hartkapseln …
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Synonyms: … 2-methoxy-5-chloroprocainamide ... 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide ... 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide …
Matched Iupac: … 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Products: … METOCLOPRAMIDA 10MG/2 ML ... PULIN INJECTION 10 mg/2 ml ... METOCLOPRAMIDA 10 MG/2 ML …
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Gly(2)-GLP-2 ... (Gly2)GLP-2 ... Glucagon-like peptide II (2-glycine) (human) …
Matched Description: … Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. ... Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). ... The significance of this substitution is that teduglutide is longer acting than endogenous GLP-2 as it …
Matched Categories: … Glucagon-like Peptide-2 (GLP-2) Agonists ... GLP-2 Analog ... Glucagon-Like Peptide 2
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Synonyms: … 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole ... 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole ... 2-methyl-1-(2-hydroxyethyl)-5-nitroimidazole …
Matched Iupac: … 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol …
Matched Mixtures name: … Stomorgyl 2 Tablet ... Metronidazole 1% / Mupirocin 2% ... Metronidazole 1% / Mupirocin 2% …
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Synonyms: … -1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure ... (6R,7R)-7-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinylcarboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl ... methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido]-3-{[( ... 1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Mixtures name: … SULZON 1 G IM ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET,2 AMPUL ... CEFPERAZON 1G IM ENJEKSIYON IÇIN TOZ IÇEREN FLAKON , FLAKON, 1 ADET, 2 AMPUL …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … CEFOBID 2 GR FLAKON ... Cefobid 2 g - Trockenstechampullen …
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Synonyms: … 2'-Deoxy-5-fluorouridine ... 5-Fluoro-2-desoxyuridine ... 5-fluoro-2'-deoxyuridine …
Matched Iupac: … 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Synonyms: … 2-Amino 6MP ... 2-Aminopurin-6-thiol ... 2-Amino-6-purinethiol …
Matched Iupac: … 2-amino-6,7-dihydro-3H-purine-6-thione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Approved
Matched Synonyms: … 2-Sulfapyridine ... 2-Sulfanilamidopyridin ... 2-Sulfanilamidopyridine …
Matched Iupac: … 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide …
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Categories: … MATE 2 Substrates …
Matched Products: … DOLPIRID 100 MG/2 ML AMPUL, 6 ADET ... ZEPRID 100 MG/ 2 ML ÇÖZELTİ İÇEREN AMPUL, 6 ADET …
Manganese is a transition metal that was first described in the 19th and 20th centuries. It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.[A263657, A263667] Manganese intake primarily occurs through the diet, as it is found at low levels in...
Approved
Nutraceutical
Matched Synonyms: … MANGANESE(2+) ... MANGANESE ION(2+) ... MANGANESE CATION (2+) …
Matched Iupac: … manganese(2+) ion …
Matched Mixtures name: … For-2 ... Spectrum 2 Cap ... Mega-vim 75 With Beta-carotene - Tablets …
Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 2-(Cyclohexylaminothio)benzothiazole ... Benzothiazyl-2-cyclohexylsulfenamide ... N-cyclohexyl-2-Benzothiazosulfenamide …
Matched Iupac: … N-(1,3-benzothiazol-2-ylsulfanyl)cyclohexanamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Glycol salicylate, also known as 2-hydroxyethyl salicylate, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic in patches used to provide relief for mild to...
Approved
Matched Synonyms: … 2-hydroxyethyl 2-oxidanylbenzoate ... 2-hydroxybenzoic acid 2-hydroxyethyl ester ... 2-hydroxyethyl salicylate …
Matched Iupac: … 2-hydroxyethyl 2-hydroxybenzoate …
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Synonyms: … 7-(Thiophene-2-acetamido)cephalosporin ... 7-(2-Thienylacetamido)cephalosporanic acid ... 7-(2'-thienylacetamido)cephalosporanic acid …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene ... -2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid ... D-2-methyl-3-mercaptopropanoyl-L-proline ... D-3-mercapto-2-methylpropanoyl-L-proline …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Displaying drugs 26 - 50 of 11667 in total