Displaying drugs 26 - 50 of 85 in total
Faricimab
Retinal vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and retinal vein occlusion (RVO) are typically caused by retinal ischemia and subsequent neovascularization (NV).[A225985, A225990, A225995] Vascular endothelial growth factor A (VEGF-A) is a well-known mediator of retinal NV, and many currently approved RVD therapies...
Approved
Investigational
Matched Description: … diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and retinal vein ... which has been developed to improve therapeutic efficacy, especially in patients that respond poorly to anti-VEGF-A ... factors, the Tie/Ang axis, comprising the transmembrane Tie-2 receptor and its soluble ligands Ang-1 …
Luspatercept
Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.[A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients...
Approved
Investigational
Matched Categories: … Immunoglobulin Fragments ... Immunoglobulin Constant Regions …
Estetrol
Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging from hormonal contraception to the treatment of menopausal symptoms. Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. It is more potent and...
Approved
Investigational
Maralixibat
Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like odevixibat.[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and...
Approved
Investigational
Matched Iupac: … -5-yl]phenoxy}methyl)phenyl]methyl}-1,4-diazabicyclo[2.2.2]octan-1-ium ... 1-{[4-({4-[(4R,5R)-3,3-dibutyl-7-(dimethylamino)-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1lambda6-benzothiepin …
Matched Categories: … Bile and Liver Therapy …
Matched Categories: … Bile and Liver Therapy …
Fondaparinux
Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Description: … Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold. ... abdominal surgery who are are at high risk of thromboembolic complications; in the treatment of deep vein ... monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural anti-coagulant …
Ursodeoxycholic acid
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Iupac: … 3bR,4S,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1- …
Matched Description: … [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional …
Matched Categories: … Bile and Liver Therapy …
Matched Description: … [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional …
Matched Categories: … Bile and Liver Therapy …
N-acetyltyrosine
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Fenofibric acid
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Categories: … Peroxisome Proliferator Receptor alpha Agonist …
Activated charcoal
Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high...
Approved
Matched Synonyms: … Charcoal activated ... Charcoal-activated ... Charcoal,activated …
Matched Name: … Activated charcoal …
Matched Description: … Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion ... The clinical applications of activated charcoal occured in the early 1800's. ... intestine transit time. …
Matched Mixtures name: … Derma Charcoal Mask ... Char-flo With Sorbitol - Sus …
Matched Categories: … medicinal charcoal ... Charcoal Preparations ... medicinal charcoal, combinations …
Matched Products: … Charcodote Tfs Sus 200mg/ml ... Charcodote-aqueous Sus 200mg/ml ... Char-flo Aqueous Base - Sus Orl 208mg/ml …
Matched Name: … Activated charcoal …
Matched Description: … Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion ... The clinical applications of activated charcoal occured in the early 1800's. ... intestine transit time. …
Matched Mixtures name: … Derma Charcoal Mask ... Char-flo With Sorbitol - Sus …
Matched Categories: … medicinal charcoal ... Charcoal Preparations ... medicinal charcoal, combinations …
Matched Products: … Charcodote Tfs Sus 200mg/ml ... Charcodote-aqueous Sus 200mg/ml ... Char-flo Aqueous Base - Sus Orl 208mg/ml …
Cephalexin
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid ... 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Products: … KEFLEX 1 G TABLETAS ... BILFASIN 1 G FILM KAPLI TABLET,10 TABLET ... BILFASIN 1 G FILM KAPLI TABLET ,16 TABLET …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Products: … KEFLEX 1 G TABLETAS ... BILFASIN 1 G FILM KAPLI TABLET,10 TABLET ... BILFASIN 1 G FILM KAPLI TABLET ,16 TABLET …
Sorbitol
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Approved
Matched Synonyms: … G-ol …
Matched Mixtures name: … Char-flo With Sorbitol - Sus ... MICROLAX LAVMAN, 10 G ... MICROLAX LAVMAN, 30 G …
Matched Mixtures name: … Char-flo With Sorbitol - Sus ... MICROLAX LAVMAN, 10 G ... MICROLAX LAVMAN, 30 G …
Dalteparin
Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Synonyms: … alpha-heparin …
Matched Description: … heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than …
Matched Products: … Fragmin 10.000 IE/1 ml - Ampullen ... -liq 2500 Iu(anti-XA)/ml ... FRAGMIN 2500 U.I/ML (ANTI-XA) VIAL DE 4 ML …
Matched Description: … heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than …
Matched Products: … Fragmin 10.000 IE/1 ml - Ampullen ... -liq 2500 Iu(anti-XA)/ml ... FRAGMIN 2500 U.I/ML (ANTI-XA) VIAL DE 4 ML …
Acenocoumarol
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one ... 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one ... 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sucralfate
Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Categories: … Anti-Ulcer Agents …
Matched Products: … Sulcrate Sus 100mg/ml ... SUCRALFATO 1 G TABLETAS ... APO-SUCRALFATE TABLET 1 g …
Matched Products: … Sulcrate Sus 100mg/ml ... SUCRALFATO 1 G TABLETAS ... APO-SUCRALFATE TABLET 1 g …
Sodium tetradecyl sulfate
An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched International brands: … Fibro-Vein …
Matched Products: … Tromboject 1% ... Trombovar Inj 1% …
Matched Products: … Tromboject 1% ... Trombovar Inj 1% …
Lidocaine
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched International brands: … Lidoject-1 …
Matched Synonyms: … alpha-diethylamino-2,6-dimethylacetanilide …
Matched Description: … As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. …
Matched Mixtures name: … Lidotral 5 Percent and Hydrocortisone 1 Percent with Peptides and Arnica ... Small Cuts and Burns ... Central Vein Catheterization Kit …
Matched Products: … Meijer Lidocaine Pain Relief Patch Assortment Small ... Burn Jel 20 mg/g ... TLC Plus Anesthetic G …
Matched Synonyms: … alpha-diethylamino-2,6-dimethylacetanilide …
Matched Description: … As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. …
Matched Mixtures name: … Lidotral 5 Percent and Hydrocortisone 1 Percent with Peptides and Arnica ... Small Cuts and Burns ... Central Vein Catheterization Kit …
Matched Products: … Meijer Lidocaine Pain Relief Patch Assortment Small ... Burn Jel 20 mg/g ... TLC Plus Anesthetic G …
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-yl]- 2-oxo-ethyl]amino]acetate ... ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- …
Matched Iupac: … -1-yl]-2-oxoethyl]amino}acetate ... ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … -1-yl]-2-oxoethyl]amino}acetate ... ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mycophenolate mofetil
Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Desirudin
Desirudin is a direct inhibitor of human thrombin. It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide...
Approved
Matched Description: … It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients …
Nadroparin
Nadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa. Nadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa. The amplification of the fibrin clotting cascade is stopped once...
Approved
Investigational
Matched Products: … FRAXIPARINE 1 ML ... FRAXIPARINE TX 1 ML ... FRAXODI 19000 IU AXA/1 ML SC ENJEKTABL SOLUSYON 2 ENJEKTOR …
Ranibizumab
Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … The development of ranibizumab first began after [bevacizumab], another anti-VEGF anticancer drug, was …
Matched Products: … 1 Ranivisio ... LUCENTİS 10 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... LUCENTİS 10 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Products: … 1 Ranivisio ... LUCENTİS 10 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... LUCENTİS 10 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Ardeparin
Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis. Ardeparin is derived via peroxide degradation of heparin extracted from porcine intestinal mucosa. Its molecular weight ranges from 2000 to 15,000 with an average molecular weight...
Approved
Investigational
Withdrawn
Matched Description: … Ardeparin is derived via peroxide degradation of heparin extracted from porcine intestinal mucosa. …
Trimethoprim
Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Mixtures name: … EUSAPRIM K SUS F KDR ... CO-TRIPIRIM 5 ML 1 AMPUL ... Nu-cotrimox Sus 40/8mg/ml …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Urinary ... MATE 1 Inhibitors ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Urinary ... MATE 1 Inhibitors ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Parnaparin
Parnaparin is an heparin of low molecular weight with antithrombotic effects.
Approved
Investigational
Cyanocobalamin
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Iupac: … {7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-yl]cobaltylium ... propyl]carbamoyl}ethyl)-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1^{2,5}.1^ ... carbamoylethyl)-3,14,19-tris(carbamoylmethyl)-4-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1- …
Matched Mixtures name: … Cavan Alpha ... Anti Fatigue Eye Drops ... B Complex W Vit C W Non-med Yeast&liver Tab …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VITAMINA B12 1 MG/ML INYECTABLE ... CIANOCOBALAMINA - VITAMINA B-12 X 1 ML ... VITAMINA B12 SOLUCION INYECTABLE 1 MG/ML …
Matched Mixtures name: … Cavan Alpha ... Anti Fatigue Eye Drops ... B Complex W Vit C W Non-med Yeast&liver Tab …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VITAMINA B12 1 MG/ML INYECTABLE ... CIANOCOBALAMINA - VITAMINA B-12 X 1 ML ... VITAMINA B12 SOLUCION INYECTABLE 1 MG/ML …
Displaying drugs 26 - 50 of 85 in total