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Displaying drugs 26 - 50 of 709 in total
Stavudine
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Synonyms: … 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine …
Matched Iupac: … 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... stavudine and lamivudine ... stavudine, lamivudine and nevirapine ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... stavudine and lamivudine ... stavudine, lamivudine and nevirapine ... Nucleic Acids, Nucleotides, and Nucleosides …
Bisoctrizole
Bisoctrizole, or methylene bis-benzotriazolyl tetramethylbutylphenol, is a broad-spectrum organic UV filter that is marketed as Tinosorb M . It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays. Bisoctrizole is not approved by the FDA, but is approved in the EU and other parts...
Approved
Matched Iupac: … benzotriazol-2-yl)-6-{[3-(2H-1,2,3-benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl}-4- …
Matched Description: … It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B ... Bisoctrizole is not approved by the FDA, but is approved in the EU and other parts of the world as a ... UV-filter in sunscreens, day care products and skin lightening products at a maximum concentration of …
Matched Description: … It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B ... Bisoctrizole is not approved by the FDA, but is approved in the EU and other parts of the world as a ... UV-filter in sunscreens, day care products and skin lightening products at a maximum concentration of …
Calfactant
Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Synonyms: … SF-RI 1 …
Matched Description: … 0.65mg of proteins including surfactant-associated proteins B and C. ... phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and ... decrease the incidence of respiratory distress syndrome, mortality due to respiratory distress syndrome, and …
Matched Products: … ALVEOFACT 50 MG/1.2 ML INTRATRAKEAL STERİL APİROJEN SÜSPANSİYON, 1 ADET …
Matched Description: … 0.65mg of proteins including surfactant-associated proteins B and C. ... phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and ... decrease the incidence of respiratory distress syndrome, mortality due to respiratory distress syndrome, and …
Matched Products: … ALVEOFACT 50 MG/1.2 ML INTRATRAKEAL STERİL APİROJEN SÜSPANSİYON, 1 ADET …
Benzalkonium
Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Description: … Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase ... This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal ... When used as an ingredient in antiseptic and disinfectant products however, it is an active antimicrobial …
Matched Salts cas: … 91080-29-4 …
Matched Mixtures name: … Hands First 4 in 1 ... Adventure Medical Kits 1-4 Person First Aid ... Ucheer B …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Target Up and Up 2-in-1 Hand Sanitizer ... B-Kleen Antibacterial Hand Wipes ... Bak 1 750 …
Matched Salts cas: … 91080-29-4 …
Matched Mixtures name: … Hands First 4 in 1 ... Adventure Medical Kits 1-4 Person First Aid ... Ucheer B …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Target Up and Up 2-in-1 Hand Sanitizer ... B-Kleen Antibacterial Hand Wipes ... Bak 1 750 …
Pasireotide
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Synonyms: … cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L …
Matched Iupac: … (3S,6R,9S,12S,15S,19R,20aS)-9-(4-aminobutyl)-15-benzyl-12-{[4-(benzyloxy)phenyl]methyl}-6-[(1H-indol- …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection ... Signifor LAR 40mg powder and solvent for suspension for injection …
Matched Iupac: … (3S,6R,9S,12S,15S,19R,20aS)-9-(4-aminobutyl)-15-benzyl-12-{[4-(benzyloxy)phenyl]methyl}-6-[(1H-indol- …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection ... Signifor LAR 40mg powder and solvent for suspension for injection …
Bendazac
Bendazac is an oxyacetic acid [A39863, A39869]. Despite possessing anti-inflammatory, anti-necrotic, choleretic, and anti-lipidemic characteristics, most research has revolved around studying and demonstrating the agent's principal action in inhibiting the denaturation of proteins - an effect that has primarily proven useful in managing and delaying the progression of ocular cataracts...
Approved
Withdrawn
Matched Iupac: … 2-[(1-benzyl-1H-indazol-3-yl)oxy]acetic acid …
Matched Description: … Despite possessing anti-inflammatory, anti-necrotic, choleretic, and anti-lipidemic characteristics, ... most research has revolved around studying and demonstrating the agent's principal action in inhibiting ... the denaturation of proteins - an effect that has primarily proven useful in managing and delaying the …
Matched Salts cas: … 81919-14-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Topical Products for Joint and Muscular Pain …
Matched Description: … Despite possessing anti-inflammatory, anti-necrotic, choleretic, and anti-lipidemic characteristics, ... most research has revolved around studying and demonstrating the agent's principal action in inhibiting ... the denaturation of proteins - an effect that has primarily proven useful in managing and delaying the …
Matched Salts cas: … 81919-14-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Topical Products for Joint and Muscular Pain …
Paclitaxel
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound …
Matched Categories: … paclitaxel and encequidar ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ICEREN FLAKON, 1 ADET ... ICEREN FLAKON, 1 ADET ... ICEREN FLAKON, 1 ADET …
Matched Categories: … paclitaxel and encequidar ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ICEREN FLAKON, 1 ADET ... ICEREN FLAKON, 1 ADET ... ICEREN FLAKON, 1 ADET …
Chloroxylenol
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Synonyms: … 4-chloro-1-hydroxy-3,5-dimethylbenzene ... 4-chloro-m-xylenol ... 3,5-dimethyl-4-chlorophenol …
Matched Iupac: … 4-chloro-3,5-dimethylphenol …
Matched Description: … disinfection and surgical instruments. ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. ... Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin …
Matched Mixtures name: … Cortane-B ... Cortaine -B Aqueous ... Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Matched Products: … Ak-1 1% ... Pro Care Spectracare Liq 1% ... Derma 1 Healthcare Hand Wash …
Matched Iupac: … 4-chloro-3,5-dimethylphenol …
Matched Description: … disinfection and surgical instruments. ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. ... Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin …
Matched Mixtures name: … Cortane-B ... Cortaine -B Aqueous ... Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Matched Products: … Ak-1 1% ... Pro Care Spectracare Liq 1% ... Derma 1 Healthcare Hand Wash …
Casimersen
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive impairment of ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is...
Approved
Investigational
Matched Description: … [A218186, L32118] In this manner, PMOs are much less susceptible to endo- and exonucleases and exhibit ... cardiac function and is invariably fatal. ... lack of functional dystrophin protein, which leads to progressive impairment of ambulatory, pulmonary, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Tetrabenazine
A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders. It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008.
Approved
Investigational
Matched Description: … It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease …
Matched Categories: … Tetrabenazine and isomer …
Matched Categories: … Tetrabenazine and isomer …
Riboflavin
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol …
Matched Description: … in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. ... Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. ... It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms …
Matched Mixtures name: … D'pantothenic Acid-B1-B2 Tab ... . #4 Vitamin and Mineral Dietary Supplement ... PNV Tabs 29-1 …
Matched Categories: … Vitamin B Complex ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … Vitamin B-2 ... B-2 Caps 100mg ... Vitamin B-2 50 Mg Tablets …
Matched Description: … in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. ... Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. ... It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms …
Matched Mixtures name: … D'pantothenic Acid-B1-B2 Tab ... . #4 Vitamin and Mineral Dietary Supplement ... PNV Tabs 29-1 …
Matched Categories: … Vitamin B Complex ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … Vitamin B-2 ... B-2 Caps 100mg ... Vitamin B-2 50 Mg Tablets …
Florbetaben F-18
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Approved
Matched Synonyms: … 4-((1E)-2-(4-(2-(2-(2-((SUP 18(F))FLUOROETHOXY)ETHOXY)ETHOXY)PHENYL)ETH-1-EN-1-YL)-N-METHYLANILINE …
Matched Iupac: … 4-[(E)-2-[4-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)phenyl]ethenyl]-N-methylaniline …
Matched Iupac: … 4-[(E)-2-[4-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)phenyl]ethenyl]-N-methylaniline …
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin ... -9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl)ethyl ... )piperidine-1-carboxylate …
Matched Iupac: … 21),2,4(9),5,7,10,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate ... diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] ... [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Topoisomerase 1 (TOP1) inhibitors …
Matched Products: … ICEREN FLAKON, 1 FLAKON ... ICEREN FLAKON, 1 FLAKON ... INFÜZYON IÇIN ÇÖZELTI IÇEREN FLAKON, 1 ADET …
Matched Iupac: … 21),2,4(9),5,7,10,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate ... diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] ... [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Topoisomerase 1 (TOP1) inhibitors …
Matched Products: … ICEREN FLAKON, 1 FLAKON ... ICEREN FLAKON, 1 FLAKON ... INFÜZYON IÇIN ÇÖZELTI IÇEREN FLAKON, 1 ADET …
Netarsudil
A Rho kinase inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous
As of December 18, 2017 the FDA approved Aerie Pharmaceutical's Rhopressa (netarsudil ophthalmic solution) 0.02% for the indication of reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Acting as both a rho...
Approved
Matched Synonyms: … (4-((1S)-1-(Aminomethyl)-2-(isoquinolin-6-ylamino)-2-oxoethyl)phenyl)methyl 2,4- dimethylbenzoate …
Matched Iupac: … {4-[(1S)-2-amino-1-[(isoquinolin-6-yl)carbamoyl]ethyl]phenyl}methyl 2,4-dimethylbenzoate …
Matched Description: … Acting as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel ... conventional trabecular pathway of aqueous humour outflow to act as an inhibitor to the rho kinase and …
Matched Salts cas: … 1253952-02-1 …
Matched Categories: … latanoprost and netarsudil ... Amino Acids, Peptides, and Proteins ... Antiglaucoma Preparations and Miotics …
Matched Iupac: … {4-[(1S)-2-amino-1-[(isoquinolin-6-yl)carbamoyl]ethyl]phenyl}methyl 2,4-dimethylbenzoate …
Matched Description: … Acting as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel ... conventional trabecular pathway of aqueous humour outflow to act as an inhibitor to the rho kinase and …
Matched Salts cas: … 1253952-02-1 …
Matched Categories: … latanoprost and netarsudil ... Amino Acids, Peptides, and Proteins ... Antiglaucoma Preparations and Miotics …
Plerixafor
Plerixafor is a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic stem cell mobilizer.[A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune...
Approved
Investigational
Matched Iupac: … 1-({4-[(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]phenyl}methyl)-1,4,8,11-tetraazacyclotetradecane …
Matched Description: … Plerixafor is a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic ... As an inhibitor of CXCR4, plerixafor blocks the binding of its ligand, stromal cell-derived factor-1- ... [A7115] Plerixafor has orphan drug status in the United States and European Union and was approved …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... MOZOBIL 20 MG/ ML ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET …
Matched Description: … Plerixafor is a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic ... As an inhibitor of CXCR4, plerixafor blocks the binding of its ligand, stromal cell-derived factor-1- ... [A7115] Plerixafor has orphan drug status in the United States and European Union and was approved …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... MOZOBIL 20 MG/ ML ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET …
Besilesomab
Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like...
Approved
Matched Description: … Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and ... various European countries like Italy, France, Germany, Spain, Portugal, Norway, Sweden, the Netherlands, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Efavirenz
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one ... (S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-(S)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl ... (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Matched Description: … ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency ... virus (HIV) type 1. ... Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring ... Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Matched Description: … ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency ... virus (HIV) type 1. ... Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring ... Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
Sonidegib
Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Synonyms: … N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide …
Matched Iupac: … N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl] …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl] …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents …
Lamivudine
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). ... A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... lamivudine and abacavir ... stavudine and lamivudine …
Matched Products: … Lamivudine and Zidovudine …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). ... A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... lamivudine and abacavir ... stavudine and lamivudine …
Matched Products: … Lamivudine and Zidovudine …
Piperonyl butoxide
Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. It has no pesticidal activity of its own, but acts to increase the activity of pesticides such as...
Approved
Vet approved
Matched Description: … It is used for the treatment of head, pubic (crab), and body lice. ... its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Reserpine
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Iupac: … -(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4( …
Matched Description: … The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 ... serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Matched Description: … The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 ... serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Mirtazapine
Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Iupac: … 5-methyl-2,5,19-triazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(15),8,10,12,16,18-hexaene …
Matched Description: … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. ... prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. …
Matched Description: … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. ... prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. …
Repotrectinib
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN ... Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin-4( ... 1,15-ETHENO-1H-PYRAZOLO(4,3-F)(1,4,8,10)BENZOXATRIAZACYCLOTRIDECIN-4(5H)-ONE, 11-FLUORO-6,7,13,14-TETRAHYDRO …
Matched Iupac: … 11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentaazatetracyclo[13.5.2.0^{4,9}.0^{18,22}]docosa-1( …
Matched Description: … This approval is based on favorable results from the TRIDENT-1 study, where the objective response rate ... was 79% in TKI-naive patients and 38% in TKI-pretreated patients respectively. ... [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentaazatetracyclo[13.5.2.0^{4,9}.0^{18,22}]docosa-1( …
Matched Description: … This approval is based on favorable results from the TRIDENT-1 study, where the objective response rate ... was 79% in TKI-naive patients and 38% in TKI-pretreated patients respectively. ... [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … [L1737]
The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. ... Food and Drug Administration approved Adcetris in March 2018 to treat adult patients with previously …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Pixantrone
Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Matched Description: … It also inhibits doxorubicinol formation in human myocardium. [3] As a result, it is believed to be less ... Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. ... Pixantrone does not bind iron and promotes the formation of reactive oxygen species to a lesser degree …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Displaying drugs 26 - 50 of 709 in total