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Displaying drugs 476 - 500 of 9061 in total
Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.
Approved
Illicit
Matched Synonyms: … 2-Ethyl-2-phenylglutarimide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Categories: … Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid ... (±)-6-chloro-α-methylcarbazole-2-acetic acid ... (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid …
Matched Iupac: … 2-(6-chloro-9H-carbazol-2-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Synonyms: … (2S)-2-Aminopentanedioic acid ... (S)-2-Aminopentanedioic acid …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene ... }-4-methylidenecyclohexan-1-ol …
Matched Mixtures name: … Acti-cal/mag 2:1 + Zinc and D Caplet ... For-2 ... Multi #2
Matched Products: … YYUX Organic Liquid Vitamin D3 Drops For Kids 4 plus years 600 IU ... ORAL AMPUL, 1 ADET ... ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL …
Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain,...
Approved
Matched Iupac: … 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid …
Matched Salts cas: … 74103-07-4
Matched Mixtures name: … Mydriatic-4
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 2-Ring …
Matched Products: … ACDOL GEL 2% ... KETRON BUSSIE 2% GEL ... ROLESEN 30 MG/2 ML INYECTABLE. …
Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Iupac: … )amino]methyl}-4-hydroxyphenyl)propanoate ... (68Ga)gallium(3+) 3-(3-{[(2-{[(5-{2-[(5-{[(5S)-5-carboxy-5-({[(1S)-1,3-dicarboxypropyl]carbamoyl}amino ... )pentyl]carbamoyl}pentyl)carbamoyl]ethyl}-2-hydroxyphenyl)methyl](carboxylatomethyl)amino}ethyl)(carboxylatomethyl …
Matched Description: … [L27006] On December 1, 2020, Ga-68 PSMA-11 was approved by the FDA as the first molecular-targeted …
Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Matched Synonyms: … 1-Deoxygalactostatin ... 1-Deoxygalactonojirimycin …
Matched Iupac: … (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … plasma metalloproteinase called ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Synonyms: … PTH(1-84) ... rPTH(1-84) ... rhPTH(1-84) …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Colchiceine is one of several metabolites of the anti-gout medication colchicine.
Approved
Experimental
Matched Iupac: … N-{14-hydroxy-3,4,5-trimethoxy-13-oxotricyclo[9.5.0.0^{2,7}]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl}acetamide …
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-((2-Ethoxyphenoxy)methyl)morpholine …
Matched Iupac: … 2-[(2-ethoxyphenoxy)methyl]morpholine …
Matched Salts cas: … 35604-67-2
Matched Categories: … MATE 1 Inhibitors ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Approved
Investigational
Matched Iupac: … (1R,3aS,3bS,7S,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H,8H …
Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy production for red...
Approved
Investigational
Matched Synonyms: … Pkr-in-1
Matched Iupac: … N-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Iupac: … 1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl ... ]amino}ethan-1-ol …
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other …
Matched Salts cas: … 152520-56-4
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic beta-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Approved
Investigational
Matched Iupac: … [(2S,4R,7R)-2-methoxy-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14 ... -tetraen-4-yl]methyl 5-bromopyridine-3-carboxylate …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds with 4 or More Rings …
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Synonyms: … 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt …
Matched Iupac: … (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate …
Matched Salts cas: … 6645-46-1 ... 220349-64-4
Matched Products: … TEFECTUS 2 G/10 ML ORAL ÇÖZELTİ, 10 ADET ... T-KARNIT 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON, 10 ADET ... METACARTIN 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON ,10 FLAKON …
The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980. However, there have been longstanding concerns that smallpox may be used as a bioweapon.[A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002. It is effective against all orthopoxviruses,...
Approved
Investigational
Matched Iupac: … N-[(1R,2R,6S,7S,8S,10R)-3,5-dioxo-4-azatetracyclo[5.3.2.0^{2,6}.0^{8,10}]dodec-11-en-4-yl]-4-(trifluoromethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Approved
Matched Synonyms: … 4-Aminoclonidine …
Matched Iupac: … 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Iopidine 1% …
Approved
Experimental
Matched Synonyms: … alpha-D-Glucopyranoside, 4-hydroxyphenyl …
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol …
Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis. This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and...
Approved
Investigational
Matched Iupac: … 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile …
Matched Description: … atom, which facilitates skin penetration and binding to the bimetal center of the phosphodiesterase 4 ... improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2
Matched Categories: … Phosphodiesterase 4 Inhibitors …
Matched Products: … Staquis Topical Ointment 2% …
Displaying drugs 476 - 500 of 9061 in total