Displaying drugs 476 - 500 of 12374 in total
Phentolamine
Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including...
Approved
Matched Salts cas: … 65-28-1 …
Matched Categories: … Peripheral alpha-1 blockers ... Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Matched Categories: … Peripheral alpha-1 blockers ... Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Penicillium chrysogenum var. chrysogenum
Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 1 ... Mold Mix 1 ... Mold Mix 1 …
Chlorquinaldol
Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment...
Approved
Matched Mixtures name: … IMPETEX %0.1 + %1 KREM, 10 G ... NERISONA-C %0,1 + %1 KREM, 10 GR ... NERISONA-C %0,1 + %1 KREM, 30 GR …
Burosumab
Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets .
The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia …
Peginterferon beta-1a
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Mixtures name: … ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... 0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1 …
Regorafenib
Regorafenib is an orally-administered inhibitor of multiple kinases. It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. Approved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017.
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sodium stibogluconate
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Iupac: … trisodium (3R,4S,5R)-1-{[(3R,4S,5R)-3-carboxylato-5-[(1R)-1,2-dihydroxyethyl]-1-oxido-2,6,7-trioxa-1- ... stibabicyclo[2.2.1]heptan-1-yl]oxy}-5-[(1R)-1,2-dihydroxyethyl]-1-hydroxy-2,6,7-trioxa-1-stibabicyclo …
Methocarbamol
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Mixtures name: … Robaxisal C 1/4 ... Robaxisal C 1/2 ... Methoxisal-C 1/8 …
rhThrombin
rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to achieving hemostasis during surgery. ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery. Thrombin is used in...
Approved
Investigational
Matched Description: … Thrombin is used in more than 1 million surgeries each year in the United States. …
Reslizumab
Reslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label]. Elevated levels of eosinophils...
Approved
Investigational
Matched Description: … Reslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced ... IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment ... By targeting the IL-5 and disrupting its signalling pathways, reslizumab aims to inhibit eosinophil maturation …
Matched Categories: … Interleukin-5 Antagonist …
Matched Categories: … Interleukin-5 Antagonist …
Ritiometan
Ritiometan is a nasal spray which is marketed by the name Nécyrane in France. It is indicated for use in viral rhinitis/ the common cold.
Approved
Ripretinib
Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST) that has not adequately responded to other kinase inhibitors such as sunitinib and imatinib. Ripretinib, also known as Qinlock, is manufactured by Deciphera Pharmaceuticals and was initially approved by the FDA on May 15, 2020....
Approved
Matched Iupac: … 1-{4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl}-3-phenylurea …
Matched Categories: … MATE 1 Inhibitors …
Matched Categories: … MATE 1 Inhibitors …
Rufinamide
Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Approved
Matched Iupac: … 1-[(2,6-difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ensulizole
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that …
Matched Mixtures name: … Careone Anti Aging Vitamin Complex 7 in 1 ... Elements Anti Aging Vitamin Complex 7 In 1 ... Shiseido Urban Environment Tinted Uv Protector 1 …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Matched Mixtures name: … Careone Anti Aging Vitamin Complex 7 in 1 ... Elements Anti Aging Vitamin Complex 7 In 1 ... Shiseido Urban Environment Tinted Uv Protector 1 …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Citric acid
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.
Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Salts cas: … 5949-29-1 …
Matched Mixtures name: … Heparin Sodium In 5% Dextrose Injection, 25000unit/500ml ... Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) …
Matched Mixtures name: … Heparin Sodium In 5% Dextrose Injection, 25000unit/500ml ... Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) …
Metipranolol
A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Approved
Matched Description: … A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. …
Matched Salts cas: … 36592-77-5 …
Matched Salts cas: … 36592-77-5 …
Lopinavir
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Iupac: … (2-oxo-1,3-diazinan-1-yl)butanamide ... (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2- …
Matched Description: … antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 ... protease enzyme but which itself cannot be cleaved, thus preventing the activity of the HIV-1 protease ... it contains a hydroxyethylene scaffold that mimics the peptide linkage typically targeted by the HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 ... protease enzyme but which itself cannot be cleaved, thus preventing the activity of the HIV-1 protease ... it contains a hydroxyethylene scaffold that mimics the peptide linkage typically targeted by the HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-{5-[(9S)-14-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin ... ,3,5,11(16),12,14-heptaen-5-yl]-1H-imidazol-2-yl}pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate ... -2-yl]-1H-imidazol-5-yl}-9-phenyl-8-oxa-10-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(17),2(7) …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Approved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 ... sustained virologic response (SVR), and have been shown to achieve a SVR between 94% and 97% for genotype 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Approved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 ... sustained virologic response (SVR), and have been shown to achieve a SVR between 94% and 97% for genotype 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Alternaria alternata
Alternaria alternata is a fungus which can provoke allergic reactions. Alternaria alternata extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 1 ... Mold Mix 1 ... Mold Mix 1 …
Oxytocin
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 …
Matched Mixtures name: … Bakumokon 5% Minoxidil …
Matched Products: … Oxytocin-Richter solution for injection 10 I.U / 1 ml ... SYNTOCINON® 5 U.I. ... Syntocinon 5 I.E. Lösung zur Injektion …
Matched Mixtures name: … Bakumokon 5% Minoxidil …
Matched Products: … Oxytocin-Richter solution for injection 10 I.U / 1 ml ... SYNTOCINON® 5 U.I. ... Syntocinon 5 I.E. Lösung zur Injektion …
Vildagliptin
Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP),...
Approved
Investigational
Matched Iupac: … (2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile …
Matched Description: … Elevated levels of GLP-1 and GIP consequently results in improved glycemic control. ... It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are ... [A232488] By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP- …
Matched Categories: … Glucagon-Like Peptide 1 ... Heterocyclic Compounds, 1-Ring …
Matched Description: … Elevated levels of GLP-1 and GIP consequently results in improved glycemic control. ... It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are ... [A232488] By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP- …
Matched Categories: … Glucagon-Like Peptide 1 ... Heterocyclic Compounds, 1-Ring …
Histamine
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Synonyms: … 5-imidazoleethylamine …
Matched Iupac: … 2-(1H-imidazol-4-yl)ethan-1-amine …
Matched Salts cas: … 51-74-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-(1H-imidazol-4-yl)ethan-1-amine …
Matched Salts cas: … 51-74-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Thiosulfuric acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Iupac: … dihydroxy-1lambda6-disulfen-1-one …
Matched Mixtures name: … Sodium Polysulthionate, 5-mthf ... Sodium polysulthionate, 5-methyltetrahydrofolate ... Sodium Polysulthionate, 5-methyltetrahydrofolate …
Matched Mixtures name: … Sodium Polysulthionate, 5-mthf ... Sodium polysulthionate, 5-methyltetrahydrofolate ... Sodium Polysulthionate, 5-methyltetrahydrofolate …
Sodium citrate
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water,
practically insoluble in alcohol. Like citric acid, it has a sour taste.
From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) ... System with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) …
Displaying drugs 476 - 500 of 12374 in total