Displaying drugs 476 - 500 of 2709 in total
Pralatrexate
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists …
Etacrynic acid
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Synonyms: … Etacrinic acid ... Etacrynic acid ... Acide étacrynique …
Matched Name: … Etacrynic acid …
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid …
Matched Description: … Henle, but also in the proximal and distal tubules. ... A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids ... etacrynic acid ... Aryloxyacetic Acid Derivatives …
Matched Products: … Ethacrynic Acid ... Ethacrynic acid …
Matched Name: … Etacrynic acid …
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid …
Matched Description: … Henle, but also in the proximal and distal tubules. ... A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids ... etacrynic acid ... Aryloxyacetic Acid Derivatives …
Matched Products: … Ethacrynic Acid ... Ethacrynic acid …
3-hydroxyanthranilic acid
An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Experimental
Matched Synonyms: … 2-Amino-3-hydroxy-benzoic acid ... 3-Oxyanthranilic acid ... 2-Amino-3-Hydroxybenzoic Acid …
Matched Name: … 3-hydroxyanthranilic acid …
Matched Iupac: … 2-amino-3-hydroxybenzoic acid …
Matched Description: … It may be a free radical scavenger and a carcinogen. …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Name: … 3-hydroxyanthranilic acid …
Matched Iupac: … 2-amino-3-hydroxybenzoic acid …
Matched Description: … It may be a free radical scavenger and a carcinogen. …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Iron sucrose
Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Synonyms: … Iron oxide saccharated ... Saccharated iron oxide ... Saccharated ferric oxide …
Matched Description: … chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... saccharated iron oxide ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Description: … chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... saccharated iron oxide ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
MPB-1523
MPB-1523 is a contrast agent comprising PEGylated iron oxide nanoparticles.
Investigational
Matched Synonyms: … PEGylated iron oxide nanoparticles …
Matched Description: … MPB-1523 is a contrast agent comprising PEGylated iron oxide nanoparticles.[L48161] …
Matched Description: … MPB-1523 is a contrast agent comprising PEGylated iron oxide nanoparticles.[L48161] …
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Description: … corticosteroid and estrogen therapy. ... tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and ... indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and …
Matched Categories: … cyclothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … corticosteroid and estrogen therapy. ... tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and ... indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and …
Matched Categories: … cyclothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Acedoben
Experimental
Matched Synonyms: … 4-(Acetylamino)benzoic acid ... Para acetamido benzoic acid ... 4-acetamidobenzoic acid …
Matched Iupac: … 4-acetamidobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 4-acetamidobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Mycophenolic acid
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Synonyms: … Acido micofenolico ... Mycophenolic acid ... Micofenolico acido …
Matched Name: … Mycophenolic acid …
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid …
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Products: … Mycophenolic Acid ... Apo-mycophenolic Acid ... Mar-mycophenolic Acid …
Matched Name: … Mycophenolic acid …
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid …
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Products: … Mycophenolic Acid ... Apo-mycophenolic Acid ... Mar-mycophenolic Acid …
Aminocaproic acid
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched Synonyms: … 6-Aminocaproic acid ... Aminocaproic acid ... 6-aminohexanoic acid …
Matched Name: … Aminocaproic acid …
Matched Iupac: … 6-aminohexanoic acid …
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Aminocaproic Acid ... Aminocaproic acid …
Matched Name: … Aminocaproic acid …
Matched Iupac: … 6-aminohexanoic acid …
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Aminocaproic Acid ... Aminocaproic acid …
Calcium oxide
Experimental
Matched Synonyms: … Calcium oxide ... Lime (calcium oxide) …
Matched Name: … Calcium oxide …
Matched Name: … Calcium oxide …
Crisdesalazine
Investigational
Matched Synonyms: … 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)benzoic acid ... Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)- …
Matched Iupac: … 2-hydroxy-5-({2-[4-(trifluoromethyl)phenyl]ethyl}amino)benzoic acid …
Matched Iupac: … 2-hydroxy-5-({2-[4-(trifluoromethyl)phenyl]ethyl}amino)benzoic acid …
Norelgestromin
Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.
Approved
Investigational
Matched Synonyms: … Norplant 3-oxime ... D-Norgestrel 3-oxime ... Levonorgestrel oxime …
Matched Mixtures name: … Norelgestromin and Ethinly Estradiol ... Norelgestromin and Ethinyl Estradiol ... Norelgestromin and Ethinyl Estradiol …
Matched Categories: … Genito Urinary System and Sex Hormones ... norelgestromin and ethinylestradiol ... Combination Contraceptives (with Estrogen and derivatives) ... Sex Hormones and Modulators of the Genital System …
Matched Mixtures name: … Norelgestromin and Ethinly Estradiol ... Norelgestromin and Ethinyl Estradiol ... Norelgestromin and Ethinyl Estradiol …
Matched Categories: … Genito Urinary System and Sex Hormones ... norelgestromin and ethinylestradiol ... Combination Contraceptives (with Estrogen and derivatives) ... Sex Hormones and Modulators of the Genital System …
Vudalimab
Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and …
Ferumoxsil
Approved
Experimental
Matched Synonyms: … Siloxane-coated superparamagnetic iron oxide …
Matched Categories: … Magnetic Iron Oxide Nanoparticles …
Matched Categories: … Magnetic Iron Oxide Nanoparticles …
Bexarotene
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid …
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid …
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid …
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and …
Matched Mixtures name: … Dr. sunmi care Duel Hyaluronic Acid Essence ... Jayjun Collagen Skin Fit Mask Step 01 Hyaluronic Acid Essence ... Lip And Hand Camellia …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment ... Mizon Hyaluronic Acid 100 …
Matched Mixtures name: … Dr. sunmi care Duel Hyaluronic Acid Essence ... Jayjun Collagen Skin Fit Mask Step 01 Hyaluronic Acid Essence ... Lip And Hand Camellia …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment ... Mizon Hyaluronic Acid 100 …
Zapnometinib
Investigational
Matched Synonyms: … Benzoic acid, 2-((2-chloro-4-iodophenyl)amino)-3,4-difluoro- …
Matched Iupac: … 2-[(2-chloro-4-iodophenyl)amino]-3,4-difluorobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 2-[(2-chloro-4-iodophenyl)amino]-3,4-difluorobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Chlormezanone
A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide ... 2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide …
Matched Categories: … Oxazol, Thiazine, and Triazine Derivatives …
Matched Categories: … Oxazol, Thiazine, and Triazine Derivatives …
Carbon monoxide
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought...
Approved
Investigational
Matched Synonyms: … carbon(II) oxide …
Matched Description: … Exhaled CO (eCO), similar to exhaled nitric oxide (eNO), has been evaluated as a candidate breath biomarker ... of pathophysiological states, including smoking status, and inflammatory diseases of the lung and other ... The DLCO test is both convenient and simple for the patient to undergo. …
Matched Categories: … Oxides …
Matched Description: … Exhaled CO (eCO), similar to exhaled nitric oxide (eNO), has been evaluated as a candidate breath biomarker ... of pathophysiological states, including smoking status, and inflammatory diseases of the lung and other ... The DLCO test is both convenient and simple for the patient to undergo. …
Matched Categories: … Oxides …
Albendazole oxide
Experimental
Matched Synonyms: … Albendazole oxide ... Albendazole S-oxide …
Matched Name: … Albendazole oxide …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Albendazole oxide …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Citric acid
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.
Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Acidum citricum ... Anhydrous citric acid ... Citric acid,anhydrous …
Matched Name: … Citric acid …
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid …
Matched Description: … [L14120] It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative ... It is an acid compound found in citrus fruits. ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Acid Preparations ... citric acid ... Carboxylic Acids …
Matched Products: … Citric Acid ... Citric Acid Wipes …
Matched Name: … Citric acid …
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid …
Matched Description: … [L14120] It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative ... It is an acid compound found in citrus fruits. ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Acid Preparations ... citric acid ... Carboxylic Acids …
Matched Products: … Citric Acid ... Citric Acid Wipes …
Fipaxalparant
Investigational
Matched Synonyms: … 1h-indene-2-carboxylic acid, 2,3-dihydro-2-((4-methoxy-3-(2-(3-methylphenyl)ethoxy)benzoyl)amino)- …
Matched Iupac: … 2-{4-methoxy-3-[2-(3-methylphenyl)ethoxy]benzamido}-2,3-dihydro-1H-indene-2-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 2-{4-methoxy-3-[2-(3-methylphenyl)ethoxy]benzamido}-2,3-dihydro-1H-indene-2-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Zinc glycinate citrate
Experimental
Matched Name: … Zinc glycinate citrate …
Matched Iupac: … zinc(2+) 2-hydroxypropane-1,2,3-tricarboxylic acid bis(2-aminoacetate) …
Matched Iupac: … zinc(2+) 2-hydroxypropane-1,2,3-tricarboxylic acid bis(2-aminoacetate) …
Zinc DL-aspartate
Experimental
Matched Name: … Zinc DL-aspartate …
Matched Iupac: … zinc(2+) bis(2-azaniumylbutanedioate) …
Matched Iupac: … zinc(2+) bis(2-azaniumylbutanedioate) …
Hydrochlorothiazide
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459]
Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting …
Matched Mixtures name: … Zinda-candesartan/hydrochlorothiazide ... Zinda-candesartan/hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … Genito Urinary System and Sex Hormones ... hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Gynecological Antiinfectives and Antiseptics ... ramipril, amlodipine and hydrochlorothiazide …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …
Matched Mixtures name: … Zinda-candesartan/hydrochlorothiazide ... Zinda-candesartan/hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … Genito Urinary System and Sex Hormones ... hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Gynecological Antiinfectives and Antiseptics ... ramipril, amlodipine and hydrochlorothiazide …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …
Displaying drugs 476 - 500 of 2709 in total