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Displaying drugs 476 - 500 of 725 in total
Experimental
Matched Name: … [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE] …
Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Categories: … Antiglaucoma Preparations and Miotics …
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and
Matched Categories: … Skin and Mucous Membrane Agents ... Arteriolar Smooth Muscle, Agents Acting On
Matched Products: … Hair essential oil ... Glemme Beard Growth Oil ... Up and Up Minoxidil …
Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients...
Approved
Matched Description: … Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various ... and marketed by several pharmaceutical companies. ... when compared to unfractionated [heparin], without increasing the risk of serious bleeding. …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … KLEXANE 10000 IE 100MG O S ... KLEXANE 4000 IE 40MG O SI. ... KLEXANE 6000 IE 60MG O SI. …
Experimental
Matched Synonyms: … 1,6-di-O-phosphono-β-D-fructofuranose …
Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic...
Approved
Matched Synonyms: … 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside) …
Matched Iupac: … -{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy ... hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one
Matched Description: … Teniposide acts primarily in the G2 and S phases of the cycle. ... Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead ... Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Matched Synonyms: … [(o-carboxyphenyl)thio]ethylmercury sodium salt ... o-(ethylmercurithio)benzoic acid sodium salt …
Matched Description: … This compound is a well-established and widely used antiseptic and antifungal agent. ... pharmaceuticals, and biological drug products, which includes vaccines. ... There has been significant concern regarding its safety and toxicity in the last several decades. …
Matched Categories: … Antiseptics and Disinfectants ... Compounds used in a research, industrial, or household setting …
A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Synonyms: … 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide ... 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide …
Matched Iupac: … 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Description: … It also tends to lower blood pressure and increase potassium loss. …
Matched Categories: … combinations of sulfonamides ... Genito Urinary System and Sex Hormones ... metolazone and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Investigational
Matched Synonyms: … cd3 epsilon chain (cd3e) on t-cells ... immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen (cea) and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Investigational
Matched Synonyms: … Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma …
Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Investigational
Matched Synonyms: … mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32 .kappa ... Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized …
Matched Description: … Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab ... in Subjects With Locally Advanced or Metastatic Tumors.). …
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … [A189462] Famotidine is used in various over-the-counter and off-label uses. ... [ranitidine] on a weight basis. ... [L11166] While oral formulations of famotidine are more commonly used, the intravenous solution of the …
Matched Mixtures name: … Care One Acid Reducer and Antacid Dual Action ... Care One Acid Reducer plus Antacid Dual Action ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Care One Acid Reducer Original Strength ... Up and Up Famotidine ... Berkley and Jensen Famotidine …
Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Matched Description: … [L50743,A263808] Its bispecificity causes T-cell activation, the release of inflammatory cytokines, and ... [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells ... and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Synonyms: … O-benzhydryldimethylaminoethanol …
Matched Description: … While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine ... seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. ... has been repurposed for use within many non-prescription over-the-counter sleep aids and cough-and-cold …
Matched Mixtures name: … Complete One Cold and Flu PE Night ... Care One Flu and Severe Cold and Cough Nighttime ... Care One Pain Relief and Pain Relief PM …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ORA ALERGI ... NERVO OPT N ... On The GO-Dose …
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxy-benzo[1,3,2]dioxabismin-4-one
Matched Iupac: … 2-hydroxy-2H,4H-benzo[d]1,3-dioxa-2-bismacyclohexan-4-one
Matched Description: … treatment of patients with _H. pylori_ infection and duodenal ulcer disease. ... Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. ... ], and [tetracycline]), which is a treatment regimen indicated for the eradication of _H. pylori_ for …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Foster and Thrive Stomach Relief …
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Synonyms: … L-OHP
Matched Description: … [A797] Oxaliplatin was approved by the FDA on January 9, 2004 and is currently marketed by Sanofi-Aventis ... [A260396] However, due to the structure of oxaliplatin, its adducts make the binding of mismatch repair ... leucovorin, known as the FOLFOX regimen, for the treatment of colorectal cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … AL OXA ® SOLUCION CONCENTRADA PARA INFUSION ... O-PLAT 50 MG POLVO LIOFILIZADO PARA INYECC ION ... O-PLAT 100 MG POLVO LIOFILIZADO PARA INYECCION …
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Synonyms: … Wool oil ... Lanolin oil
Matched Description: … Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides. …
Matched Mixtures name: … Optilube Ont ... Therapeutic Bath Oil ... A and D Diaper Rash and Skin Protectant …
Matched Categories: … Basic Ointments and Protectants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Approved
Matched Description: … It is typically extracted from ilmenite, rutile and anatase. ... Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium ... It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. …
Matched Mixtures name: … Avobenzone, Octinoxate, Titanium Dioxide ... Avobenzone, Octinoxate, Titanium Dioxide ... Avobenzone, Octinoxate, Titanium Dioxide …
Matched Categories: … Astringents and Deodorants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Quick and Clean Oil Free Sun Spf35 Pa ... Oil Of Olay Complete Radiance Foundation ... (oil-free)p2 …
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation ... Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. …
Matched Mixtures name: … DESENFRIOL-ON GRAGEAS REPETABS ... Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Loratadine ODT ... Loratadine OD ... Sunmark Loratadine ODT
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( ... [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Synonyms: … S(O)Me2 …
Matched Description: … Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation ... of pharmaceuticals. ... Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Genito Urinary System and Sex Hormones ... Topical Products for Joint and Muscular Pain …
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
Matched Synonyms: … 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine …
Matched Description: … and skeletal muscle relaxant properties. ... disorders, etizolam is marketed in Japan, Italy and India. ... It is not approved for use by FDA in the US; however it remains unscheduled in several states and is …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids ... Pyrethrins component of rid mousse …
Matched Description: … The active compound is absorbed by the lice and destroys them by acting on their nervous systems but ... Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... is thought to exert minimal effect on humans. …
Matched Mixtures name: … Care One Lice Killing ... Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and
Matched Description: … Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …
A disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose. [PubChem]
Experimental
Matched Synonyms: … 4-o-beta-d-glucopyranosyl-d-glucose ... 4-O-β-D-glucopyranosyl-D-glucopyranose …
Matched Iupac: … (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy} …
Matched Description: … Obtained from the partial hydrolysis of cellulose. [PubChem] ... A disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 476 - 500 of 725 in total