Displaying drugs 501 - 525 of 10774 in total
Burosumab
Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets .
The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia …
Samarium (153Sm) lexidronam
Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of the body's organs or to treat certain diseases.Samarium...
Approved
Investigational
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)(methyl)amine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic …
Fezolinetant
Vasomotor symptoms (VMS), more colloquially known as hot flashes or night sweats, are some of the most common symptoms in menopause. With a median duration of 7.4 years, vasomotor symptoms are also the most common reasons why women seek treatments for menopausal issues.[A259591,A259596] Although mostly considered a nuisance, vasomotor symptoms...
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tigecycline
Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Products: … INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON,FLAKON, 1 ADET …
Hydroxyethyl cellulose
Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as...
Approved
Matched Iupac: … 1-{[3,4,5-tris(2-hydroxypropoxy)-6-{[4,5,6-tris(2-hydroxypropoxy)-2-[(2-hydroxypropoxy)methyl]oxan-3- …
Matched Salts name: … Hydroxyethyl cellulose (1500 MPa.s at 1%) ... Hydroxyethyl cellulose (2000 MPa.s at 1%) ... Hydroxyethyl cellulose (3000 MPa.s at 1%) ... Hydroxyethyl cellulose (4000 MPa.s at 1%) ... Hydroxyethyl cellulose (5000 MPa.s at 1%) …
Matched Salts name: … Hydroxyethyl cellulose (1500 MPa.s at 1%) ... Hydroxyethyl cellulose (2000 MPa.s at 1%) ... Hydroxyethyl cellulose (3000 MPa.s at 1%) ... Hydroxyethyl cellulose (4000 MPa.s at 1%) ... Hydroxyethyl cellulose (5000 MPa.s at 1%) …
Lopinavir
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Iupac: … [2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1- …
Matched Description: … antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 ... protease enzyme but which itself cannot be cleaved, thus preventing the activity of the HIV-1 protease ... it contains a hydroxyethylene scaffold that mimics the peptide linkage typically targeted by the HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 ... protease enzyme but which itself cannot be cleaved, thus preventing the activity of the HIV-1 protease ... it contains a hydroxyethylene scaffold that mimics the peptide linkage typically targeted by the HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ioxaglic acid
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Quinine
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in...
Approved
Matched Iupac: … (R)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Mixtures name: … IRUDERM 1 …
Matched Mixtures name: … IRUDERM 1 …
Riluzole
A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Oxytocin
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 …
Matched Products: … Oxytocin-Richter solution for injection 10 I.U / 1 ml …
Matched Products: … Oxytocin-Richter solution for injection 10 I.U / 1 ml …
Metipranolol
A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Approved
Matched Description: … A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. …
Pretomanid
Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. Research in recent years has been geared toward the development of novel therapies that target persistent forms of this disease, which have shown resistance to standard therapy...
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lifitegrast
Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Iupac: … (2S)-2-{[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinolin-6-yl]formamido}-3-(3- …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists …
Flutamide
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Approved
Investigational
Thiosulfuric acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Iupac: … dihydroxy-1lambda6-disulfen-1-one …
Tapinarof
Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Levamlodipine
Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive medication. Levamlodipine belongs to the dihydropyridine group of calcium channel blockers. This medication was first marketed in Russia and India before being granted FDA approval. The names S-amlodipine and levamlodipine may be used interchangeably as both...
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Turpentine
Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis reactions. Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene...
Approved
Experimental
Matched Mixtures name: … VICKS VAPORUB BUHARLASAN MERHEM, 1 ADET …
Ensulizole
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Mixtures name: … Careone Anti Aging Vitamin Complex 7 in 1 ... Elements Anti Aging Vitamin Complex 7 In 1 ... Shiseido Urban Environment Tinted Uv Protector 1 …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Tazobactam
Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections.
Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Iupac: … (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane …
Matched Mixtures name: … ZERBAXA ® 1 G/0.5 G ... ZERBAXA ® 1 G/0.5 G ... ENJEKSIYONLUK LIYOFILIZE TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Mixtures name: … ZERBAXA ® 1 G/0.5 G ... ZERBAXA ® 1 G/0.5 G ... ENJEKSIYONLUK LIYOFILIZE TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Technetium Tc-99m sestamibi
Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Iupac: … technetium(1+) ion hexakis(1-isocyano-2-methoxy-2-methylpropane) …
Matched Description: … Currently available within a preparation kit for injection, Technetium Tc 99m Sestamibi is indicated for: 1) …
Matched Description: … Currently available within a preparation kit for injection, Technetium Tc 99m Sestamibi is indicated for: 1) …
Arbutamine
Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease in patients who cannot exercise adequately .
Approved
Matched Iupac: … 4-[(1R)-1-hydroxy-2-{[4-(4-hydroxyphenyl)butyl]amino}ethyl]benzene-1,2-diol …
Matched Categories: … Adrenergic beta-1 Receptor Agonists …
Matched Categories: … Adrenergic beta-1 Receptor Agonists …
Levonordefrin
Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Approved
Matched Iupac: … 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol …
Matched Mixtures name: … 2% Polocaine Dental With Levonordefrin 1:20,000 …
Matched Mixtures name: … 2% Polocaine Dental With Levonordefrin 1:20,000 …
Acetylcysteine
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168]
Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Displaying drugs 501 - 525 of 10774 in total