Displaying drugs 501 - 525 of 6310 in total
Varenicline
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Iupac: … 5,8,14-triazatetracyclo[10.3.1.0^{2,11}.0^{4,9}]hexadeca-2(11),3,5,7,9-pentaene …
Matched Description: … Varenicline is a prescription medication used to treat smoking addiction. ... A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. ... Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine …
Matched Mixtures name: … CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … และ 1 มก.) ... แชมปิกซ์ (1 มก.) ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …
Matched Description: … Varenicline is a prescription medication used to treat smoking addiction. ... A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. ... Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine …
Matched Mixtures name: … CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … และ 1 มก.) ... แชมปิกซ์ (1 มก.) ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …
Iron sucrose
Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Iupac: … pentairon(3+) ion disodium (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan ... -2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol trihydrate hydroxide octaoxidandiide …
Matched Description: … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with …
Matched Products: … FE-BACK INJECTION 2% "N.K." ... HIERRO SACARATO EQUIVALENTE A HIERRO ELEMENTAL 100 MG/ 5ML. …
Matched Description: … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with …
Matched Products: … FE-BACK INJECTION 2% "N.K." ... HIERRO SACARATO EQUIVALENTE A HIERRO ELEMENTAL 100 MG/ 5ML. …
Daptomycin
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21 ... -decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2R)-3-carbamoyl ... -2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid ... -bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29 …
Matched Description: … Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive ... non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... myopathy but was resumed in 1997 when Cubist Pharmaceuticals Inc. licensed daptomycin; it was found that a …
Matched Products: … CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... XAPTO 350 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... XAPTO 500 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Matched Description: … Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive ... non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... myopathy but was resumed in 1997 when Cubist Pharmaceuticals Inc. licensed daptomycin; it was found that a …
Matched Products: … CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... XAPTO 350 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... XAPTO 500 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Synonyms: … 4-(6-Methoxy-2-naphthyl)-2-butanone ... 4-(6-Methoxy-2-naphthalenyl)-2-butanone …
Matched Iupac: … 4-(6-methoxynaphthalen-2-yl)butan-2-one …
Matched Description: … [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone ... [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite ... acting as a potent COX inhibitor similar in structure to [naproxen]. …
Matched Mixtures name: … NuDroxiPAK N-500 …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Products: … DOLORSIN 1 G …
Matched Iupac: … 4-(6-methoxynaphthalen-2-yl)butan-2-one …
Matched Description: … [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone ... [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite ... acting as a potent COX inhibitor similar in structure to [naproxen]. …
Matched Mixtures name: … NuDroxiPAK N-500 …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Products: … DOLORSIN 1 G …
Ombitasvir
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … -2,1-diyl[(2S)-3-methyl-1-oxobutane-1,2-diyl]})biscarbamate ... dimethyl ([(2S,5S)-1-(4-tert-butylphenyl)pyrrolidine-2,5-diyl]bis{(4,1-phenylene)carbamoyl(2S)pyrrolidine …
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-({4-[(2S,5S)-1-(4-tert-butylphenyl)-5-{4-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino ... ]-3-methylbutanoyl]pyrrolidine-2-amido]phenyl}pyrrolidin-2-yl]phenyl}carbamoyl)pyrrolidin-1-yl]-3-methyl ... -1-oxobutan-2-yl]carbamate …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). ... indicated in combination with Ribavirin for the treatment of patients with genotype 4 chronic hepatitis C virus …
Matched Categories: … Hepatitis C Virus NS5A Inhibitor …
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-({4-[(2S,5S)-1-(4-tert-butylphenyl)-5-{4-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino ... ]-3-methylbutanoyl]pyrrolidine-2-amido]phenyl}pyrrolidin-2-yl]phenyl}carbamoyl)pyrrolidin-1-yl]-3-methyl ... -1-oxobutan-2-yl]carbamate …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). ... indicated in combination with Ribavirin for the treatment of patients with genotype 4 chronic hepatitis C virus …
Matched Categories: … Hepatitis C Virus NS5A Inhibitor …
Juglans nigra pollen
Juglans nigra pollen is the pollen of the Juglans nigra plant. Juglans nigra pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 11 Tree Pollen Mix ... 11 Tree Pollen Mix ... 11 Tree Pollen Mix …
Difluprednate
Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti.
Approved
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate ... (1R,3aS,3bS,5S,9aS,9bR,10S,11aS)-1-[2-(acetyloxy)acetyl]-5,9b-difluoro-10-hydroxy-9a,11a-dimethyl-7-oxo …
Matched Description: … It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. ... Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated …
Matched Description: … It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. ... Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated …
Corynebacterium diphtheriae
Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Approved
Investigational
Matched Description: … formaldehyde and diafiltered. ... The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with …
Matched Categories: … Inactivated Corynebacterium Diphtheriae Vaccine …
Matched Categories: … Inactivated Corynebacterium Diphtheriae Vaccine …
Efalizumab
Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. The FDA approved efalizumab in 2003. It was later withdrawn...
Approved
Investigational
Withdrawn
Matched Description: … Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ... ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. ... It was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy …
Cetalkonium
Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved
Matched Description: … [A27143] It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and ... Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows ... [L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant …
Matched Salts cas: … 3529-04-2 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Salts cas: … 3529-04-2 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bexagliflozin
Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor.[A256408,A256413,L44758] Similar to other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a methylene bridge. SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such as SGLT1, SGLT2 is...
Approved
Investigational
Matched Synonyms: … D-glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-, (1s)- ... (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-(4-chloro-3-{[4-(2-cyclopropoxyethoxy)phenyl]methyl}phenyl)-6-(hydroxymethyl)oxane …
Matched Description: … Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. ... Its use is not recommended in patients with type 1 diabetes since it may increase their risk of diabetic ... other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Diabetes Mellitus, Type 2, drug therapy ... Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-(4-chloro-3-{[4-(2-cyclopropoxyethoxy)phenyl]methyl}phenyl)-6-(hydroxymethyl)oxane …
Matched Description: … Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. ... Its use is not recommended in patients with type 1 diabetes since it may increase their risk of diabetic ... other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Diabetes Mellitus, Type 2, drug therapy ... Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Technetium Tc-99m nofetumomab merpentan
Technetium Tc-99m nofetumomab merpentan (Tc-99m nm) consists of a Fab fragment of an IgG2b of the pancarcinoma murine antibody NR-LU-10. The NR-LU-10 antibody is directed against a 40 kDa glycoprotein antigen expressed in a variety of cancers and some normal tissues.[FDA label] Tc-99m nm was developed by Boehringer Ingelheim Pharma...
Approved
Withdrawn
Matched Description: … [A32115] The NR-LU-10 antibody is directed against a 40 kDa glycoprotein antigen expressed in a variety ... It was after discontinued on August 13, 2013, but in the 2018 FDA submission list, it can be found as ... a substance type II (Drug substance) with an active status. …
Fursultiamine
Compound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.
Approved
Matched Iupac: … N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(2E)-5-hydroxy-3-{[(oxolan-2-yl)methyl]disulfanyl}pent- ... 2-en-2-yl]formamide …
Matched Description: … Fursultiamine is a vitamin B1 derivative. …
Matched Salts cas: … 2105-43-3 …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring …
Matched Description: … Fursultiamine is a vitamin B1 derivative. …
Matched Salts cas: … 2105-43-3 …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring …
Fentanyl
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone.
Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide ... N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide ... N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose ... [L6748] Opioid overdoses kill an average of 11 Canadians daily. ... Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... DUROGESIC SMAT 12 A 2.1MG ... DUROGESIC SMAT 25 A 4.2MG …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose ... [L6748] Opioid overdoses kill an average of 11 Canadians daily. ... Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... DUROGESIC SMAT 12 A 2.1MG ... DUROGESIC SMAT 25 A 4.2MG …
Cyclizine
A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)
Approved
Matched Synonyms: … 1-Benzhydryl-4-methylpiperazin ... (±)-1-diphenylmethyl-4-methylpiperazine ... 1-(Diphenylmethyl)-4-methylpiperazine …
Matched Iupac: … 1-(diphenylmethyl)-4-methylpiperazine …
Matched Description: … A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced …
Matched Salts cas: … 303-25-3 …
Matched Mixtures name: … Echnatol B 6 - Dragees …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-(diphenylmethyl)-4-methylpiperazine …
Matched Description: … A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced …
Matched Salts cas: … 303-25-3 …
Matched Mixtures name: … Echnatol B 6 - Dragees …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Synonyms: … (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol ... 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Description: … It is also found in plants and is used pharmacologically as a sympathomimetic. ... Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic …
Matched Mixtures name: … XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUS …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
Matched Products: … N-EPI ... N-EPI® 1mg/ml Concentrate for Solution for Infusion ... NORADRENALINA 1 MG / ML …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Description: … It is also found in plants and is used pharmacologically as a sympathomimetic. ... Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic …
Matched Mixtures name: … XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUS …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
Matched Products: … N-EPI ... N-EPI® 1mg/ml Concentrate for Solution for Infusion ... NORADRENALINA 1 MG / ML …
Levocarnitine
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Synonyms: … 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt …
Matched Iupac: … (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate …
Matched Salts cas: … 6645-46-1 …
Matched Products: … TEFECTUS 2 G/10 ML ORAL ÇÖZELTİ, 10 ADET ... T-KARNIT 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON, 10 ADET ... METACARTIN 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON ,10 FLAKON …
Matched Iupac: … (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate …
Matched Salts cas: … 6645-46-1 …
Matched Products: … TEFECTUS 2 G/10 ML ORAL ÇÖZELTİ, 10 ADET ... T-KARNIT 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON, 10 ADET ... METACARTIN 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON ,10 FLAKON …
Valproic acid
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Synonyms: … 2-n-propyl-n-valeric acid ... 2-Propylvaleric Acid ... 2-propyl-pentanoic acid …
Matched Iupac: … 2-propylpentanoic acid …
Matched Description: … nearly a century. ... is the subject of many clinical trials in a variety of cancer types. ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for …
Matched Categories: … UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A3 Substrates with a Narrow Therapeutic Index ... UGT1A6 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... UGT2B7 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 2-propylpentanoic acid …
Matched Description: … nearly a century. ... is the subject of many clinical trials in a variety of cancer types. ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for …
Matched Categories: … UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A3 Substrates with a Narrow Therapeutic Index ... UGT1A6 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... UGT2B7 Substrates with a Narrow Therapeutic Index …
Testolactone
An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Approved
Investigational
Matched Synonyms: … 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid δ-lactone ... 1-dehydrotestololactone ... delta(1)-testololactone …
Matched Iupac: … 4bR,10aR,10bS,12aS)-10a,12a-dimethyl-2H,3H,4H,4aH,4bH,5H,6H,8H,10aH,10bH,11H,12H,12aH-phenanthro[2,1-b] …
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …
Matched Iupac: … 4bR,10aR,10bS,12aS)-10a,12a-dimethyl-2H,3H,4H,4aH,4bH,5H,6H,8H,10aH,10bH,11H,12H,12aH-phenanthro[2,1-b] …
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …
Deflazacort
Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD). It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA.[L6694,FDA label]
Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which...
Approved
Investigational
Matched Iupac: … 2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸ ... ]icosa-6,14,17-trien-8-yl]-2-oxoethyl acetate …
Matched Description: … Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular …
Matched Description: … Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular …
Safinamide
Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Approved
Investigational
Matched Iupac: … (2S)-2-[({4-[(3-fluorophenyl)methoxy]phenyl}methyl)amino]propanamide …
Matched Categories: … Monoamine Oxidase B Inhibitors ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Categories: … Monoamine Oxidase B Inhibitors ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Vemurafenib
Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Iupac: … N-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide …
Matched Description: … Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E ... After approval, Roche in collaboration with Genentech launched a broad development program. [L1012] …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... B-Raf serine-threonine kinase (BRAF) inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E ... After approval, Roche in collaboration with Genentech launched a broad development program. [L1012] …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... B-Raf serine-threonine kinase (BRAF) inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Copanlisib
Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. Copanlisib was granted accelerated...
Approved
Investigational
Matched Synonyms: … 2-AMINO-N-(7-METHOXY-8-(3-(MORPHOLIN-4-YL)PROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL(PYRIMIDINE ... 2-AMINO-N-(7-METHOXY-8-(3-MORPHOLIN-4-YLPROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE- ... 5-PYRIMIDINECARBOXAMIDE, 2-AMINO-N-(2,3-DIHYDRO-7-METHOXY-8-(3-(4-MORPHOLINYL)PROPOXY)IMIDAZO(1,2-C)QUINAZOLIN …
Matched Iupac: … 2-amino-N-{7-methoxy-8-[3-(morpholin-4-yl)propoxy]-2H,3H-imidazo[1,2-c]quinazolin-5-yl}pyrimidine-5-carboxamide …
Matched Description: … Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity ... PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphatidylinositol-3-kinase (Pi3K) inhibitors ... MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Iupac: … 2-amino-N-{7-methoxy-8-[3-(morpholin-4-yl)propoxy]-2H,3H-imidazo[1,2-c]quinazolin-5-yl}pyrimidine-5-carboxamide …
Matched Description: … Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity ... PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphatidylinositol-3-kinase (Pi3K) inhibitors ... MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Aminocaproic acid
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Indium In-111 pentetreotide
Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.
Approved
Investigational
Matched Iupac: … (111In)indium(3+) ion 2-{[2-({[(1-{[10-(4-aminobutyl)-16-benzyl-4-[(1,3-dihydroxybutan-2-yl)-C-hydroxycarbonimidoyl ... ]-6,12,15,18-tetrahydroxy-7-(1-hydroxyethyl)-13-[(1H-indol-3-yl)methyl]-9-oxido-1,2-dithia-5,8,11,14,17 ... -pentaazacycloicosa-5,8,11,14,17-pentaen-19-yl]-C-hydroxycarbonimidoyl}-2-phenylethyl)-C-hydroxycarbonimidoyl …
Displaying drugs 501 - 525 of 6310 in total