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Displaying drugs 501 - 525 of 961 in total

Bromfenac

Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts name: … Bromfenac sodium …
Matched Products: … Bromfenac Sodium …

Edetate calcium disodium anhydrous

Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Calcium Edetate de Sodium …

Magnesium aspartate hydrochloride

Experimental
Matched Name: … Magnesium aspartate hydrochloride …
Matched Iupac: … magnesium(2+) (2S)-2-aminobutanedioate hydrochloride …
Matched Salts name: … Magnesium aspartate hydrochloride trihydrate …

Elapegademase

Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND …
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Aluminum zirconium tetrachlorohydrex gly

Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Ap 22% (regular,sport,musk and Unscented) ... Mitchum Clear Gel A.P. and Deod.supersport ... Body Satin Antiperspirant and Deodorant …

Fimaporfin

Investigational
Matched Synonyms: … or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid, mixture of three isomers a, b and …

Mozafancogene autotemcel

RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …

CP-12

Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …

Vasopressin

Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Description: … renal fluid reuptake by acting through V1 and V2 cellular receptors. ... [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and ... hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Vasopressin in 0.9% Sodium Chloride …

Prizloncabtagene autoleucel

C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational
Matched Synonyms: … , non-replicating lentiviral vector, encoding a bispecific chimeric antigen receptor targeting CD19 and …

Pacmilimab

Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND …
Matched Description: … Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). ... Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor …

Cefuroxime

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Salts name: … Cefuroxime sodium …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose ... Cefuroxime Sodium ... Cefuroxime sodium …

Diethylpropion

A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Salts name: … Diethylpropion hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Diethylpropion Hydrochloride ... Diethylpropion Hydrochloride ER ... Diethylpropion HydrochlorideER ER …

Pectin

Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium …
Matched Mixtures name: … Cepacol Sore Throat and Coating ... Kaolin and Pectin Susp ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …

Cefoperazone

Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and …
Matched Mixtures name: … CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM …
Matched Salts name: … Cefoperazone sodium …
Matched Products: … CEFOPERAZONE SODIUM …

Ceftizoxime

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Description: … It has few side effects and is reported to be safe and effective in aged patients and in patients with ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Salts name: … Ceftizoxime sodium …
Matched Products: … CEFTIZOXIME SODIUM …

Factor IX Complex (Human)

Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …

Atidarsagene autotemcel

Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and …
Matched Salts name: … Flurbiprofen sodium …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Flurbiprofen Sodium ... Strepsils MaxPro Honey and Lemon lozenges 8.75mg …

Sodium phosphate, monobasic, unspecified form

Approved
Matched Name: … Sodium phosphate, monobasic, unspecified form …
Matched Mixtures name: … Up and Up Ready To Use Enema ... Pure and Gentle Laxative ... Foster and Thrive Ready to Use Saline Laxative …

Nogapendekin alfa

Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Lansoprazole

Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies...
Approved
Investigational
Matched Description: … Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally ... [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective ... at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Alimentary Tract and Metabolism ... lansoprazole, amoxicillin and levofloxacin ... lansoprazole, clarithromycin and tinidazole ... lansoprazole, amoxicillin and metronidazole ... lansoprazole, tetracycline and metronidazole …
Matched Products: … Up and Up Lansoprazole ... Berkley and Jensen Lansoprazole ... Foster and Thrive Acid Reducer …

Bivalirudin

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Description: … monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Bivalirudin in 0.9% Sodium Chloride …

Hydrochloric acid

Experimental
Matched Synonyms: … Hydrochloric acid …
Matched Name: … Hydrochloric acid …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... hydrochloric acid ... hydrochloric acid ... Blood Substitutes and Perfusion Solutions …

Hyaluronic acid

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Description: … oral, topical, and injectable forms. ... Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and ... Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “ …
Matched Mixtures name: … Hyaluronic Acid 60mg and Lidocaine 2% PF ... ELDEEN AGE TWENTY ONE MifitPatch and Serum ... ELDEEN AGE TWENTY ONE MifitPatch and Serum …
Matched Salts name: … Hyaluronate sodium ... Sodium hyaluronate …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Matched Products: … LUBRAVISC (1% SODIUM HYALURONATE) ... MICRODROPS (0.2% SODIUM HYALURONATE) ... DERMAVISC DF (0.6% SODIUM HYALURONATE) …
Displaying drugs 501 - 525 of 961 in total