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Displaying drugs 526 - 550 of 12411 in total

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Iupac: … ]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14 ... (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl …
Matched Salts cas: … 121470-24-4 …
Matched Products: … ZARET 4% POLVO PARA RECONSTITUIR (AZITROMICINA) ... ZITROTEK FILM KAPLI TABLET, 2 ADET ... AZİTROTEK 500 MG FİLM TABLET, 2 TABLET …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Iupac: … 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Matched Description: … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing …

Ethchlorvynol

Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Approved
Illicit
Withdrawn
Matched Synonyms: … 1-chloro-3-ethyl-1-penten-4-yn-3-ol ... 1-Chloro-3-ethyl-pent-1-en-4-yn-3-ol …
Matched Iupac: … (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol …

Diamorphine

Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under...
Approved
Illicit
Investigational
Matched Iupac: … (1S,5R,13R,14S,17R)-10-(acetyloxy)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …

Ferric subsulfate

Ferric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin biopsies.
Approved
Experimental
Matched Description: … It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin biopsies. …

Caffeine

Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Mixtures name: … BINTANG TOEDJOE PUYER NO.16 ... GRIPAC 4® ... GRIPAC 4® …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Pentoxifylline

Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Chlorpropamide

Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … N-(4-chlorophenylsulfonyl)-N'-propylurea ... 4-chloro-N-((propylamino)carbonyl)benzenesulfonamide ... 4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …

Manganese citrate

Approved
Experimental
Matched Iupac: … trimanganese(2+) bis(2-hydroxypropane-1,2,3-tricarboxylate) …
Matched Mixtures name: … Tricare Prenatal 2-part Daily Prenatal Vitamin System …

Tolbutamide

Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 3-(p-Tolyl-4-sulfonyl)-1-butylurea ... N-(4-Methylphenylsulfonyl)-N'-butylurea ... N-(4-Methylbenzenesulfonyl)-N'-butylurea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …

Sunitinib

Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formulation....
Approved
Investigational
Matched Iupac: … N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Human immunoglobulin G

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Products: … BERIGLOBINA P X 2 ML INYECTABLE ... GENIVIG HUMAN IMMUNGLOBULIN (PH 4) 5 G/100 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …

Parecoxib

Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral...
Approved
Matched Synonyms: … N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide …
Matched Iupac: … N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl]propanamide …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …

Faricimab

Retinal vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and retinal vein occlusion (RVO) are typically caused by retinal ischemia and subsequent neovascularization (NV).[A225985, A225990, A225995] Vascular endothelial growth factor A (VEGF-A) is a well-known mediator of retinal NV, and many currently approved RVD therapies...
Approved
Investigational
Matched Description: … However, another set of factors, the Tie/Ang axis, comprising the transmembrane Tie-2 receptor and its ... soluble ligands Ang-1 and Ang-2, has been shown to play critical roles in mediating VEGF-A-induced NV ... /sub>-derived bispecific antibody capable of simultaneously binding to and depleting VEGF-A and Ang-2, …

Technetium Tc-99m sestamibi

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Iupac: … technetium(1+) ion hexakis(1-isocyano-2-methoxy-2-methylpropane) …
Matched Description: … by localizing myocardial ischemia (reversible defects) and infarction (non-reversible defects); and 2) …

Infigratinib

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational
Matched Iupac: … 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea …
Matched Description: … locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 …
Matched Categories: … MATE 2 Inhibitors ... Fibroblast Growth Factor 2, antagonists & inhibitors …

Interferon alfa-n1

Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational

Acetic acid

Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or...
Approved
Matched Mixtures name: … AMINOMIX 2 SOLÜSYON, 1000 ML ... AMINOMIX 2 SOLÜSYON, 2000 ML ... AMINOMIX 2 SOLÜSYON, 15000 ML …

Influenza B virus B/Brisbane/46/2015 hemagglutinin antigen (propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved

Sutimlimab

Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Description: … in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4° ... M (IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4° …

Nalbuphine

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Iupac: … (1S,5R,13R,14S,17S)-4-(cyclobutylmethyl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Salts cas: … 23277-43-2 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …

Isoniazid

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Synonyms: … 4-pyridinecarbohydrazide ... Pyridine-4-carboxylic acid hydrazide …
Matched Iupac: … pyridine-4-carbohydrazide …
Matched Mixtures name: … ริมสตาร์ 4 - FDC ... AkuriT-4 TABLET ... RIFAMPICIN 75 MG / ISONIAZID 50 MG (FDC 2 ANAK) …

Pregabalin

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational

Calcipotriol

Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Approved
Matched Iupac: … -1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol ... (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-octahydro …
Matched Mixtures name: … Calcipotriene 0.005% / Niacinamide 4% ... Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% …

Neisseria meningitidis serogroup b nhba fusion protein antigen

Approved
Matched Mixtures name: … BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET 2 İĞNELİ …
Displaying drugs 526 - 550 of 12411 in total