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Displaying drugs 551 - 575 of 5671 in total
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Iupac: … 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin ... -4-one …
Matched Description: … D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical ... mental health conditions including schizophrenia and bipolar disorder. ... Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Inhibitors ... Cytochrome P-450 CYP2D6 Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Products: … RISPERIDONE DI RENZO ... LOST PER ... PMS-risperidone …
Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over 68Ga-labeled somatostatin analogs for positron emission tomography (PET). Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron...
Approved
Matched Synonyms: … Copper 64-DOTA-tate ... Copper Cu-64 dotatate ... Copper dotatate Cu-64 …
Matched Name: … Copper oxodotreotide Cu-64 …
Matched Iupac: … ]carbamoyl}-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18 ... (64Cu)copper(2+) 2-[7-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl ... pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl)-4- …
Matched Description: … Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over ... [A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several ... Further, PET using Copper Cu 64 dotatate has been found to perform better than the current gold standard …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Copper Radioisotopes …
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Synonyms: … p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide ... 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide …
Matched Iupac: … 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl]benzene-1-sulfonamide …
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and ... lead to high blood pressure. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Inducers ... Cytochrome P-450 CYP3A Inducers …
Matched Products: … PMS-bosentan …
Experimental
Matched Synonyms: … 4-[2,6,8-trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]butyl dihydrogen phosphate …
Matched Name: … 1-deoxy-1-{2,6,8-trioxo-7-[4-(phosphonooxy)butyl]-1,2,3,6,7,8-hexahydro-9H-purin-9-yl}-D-arabinitol …
Matched Iupac: … (4-{2,6,8-trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2,3,6,7,8,9-hexahydro-1H-purin-7-yl}butoxy …
Investigational
Matched Synonyms: … 2,2-dimethylpropanoic acid 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy) ... Propanoic acid, 2,2-dimethyl-, 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy …
Matched Iupac: … {[({4-[(3-benzyl-4-hydroxyphenyl)methyl]-3,5-dimethylphenoxy}methyl)({[(2,2-dimethylpropanoyl)oxy]methoxy …
Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Synonyms: … (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid ... N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Matched Description: … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
Matched Salts cas: … 150915-40-5 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Approved
Matched Iupac: … 4-amino-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Products: … POMARZA 3 (POMALIDOMIDE CAPSULES 3mg) ... POMARZA 4 (POMALIDOMIDE CAPSULES 4mg) ... POMALYST 3 MG …
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid ... 2-amino-3-(4-bromobenzoyl)benzeneacetic acid …
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid …
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts cas: … 120638-55-3
Matched Salts name: … Bromfenac sodium
Matched Products: … Bromsite 0.075% ... Bromfenac Sodium
Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids and varicose veins . Sodium tetradecyl sulfate has been widely used since the 1950s, and in...
Approved
Matched International brands: … Fibro-Vein 3% …
Matched Synonyms: … 7-Ethyl-2-methyl-4-undecanol sulfate …
Matched Iupac: … [(7-ethyl-2-methylundecan-4-yl)oxy]sulfonic acid …
Matched Description: … effects and a 30% incidence of post-sclerosis pigmentation that resolved within a few months [L2035]. ... Sodium tetradecyl sulfate has been widely used since the 1950s, and in 1978 the first successful report ... in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids …
Matched Products: … Veinfibro 3 % Injektionslösung ... Sodium Tetradecyl Sulfate ... (sotradecol) Sodium Tetradecyl Sulfate …
Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications such as...
Approved
Vet approved
Matched Synonyms: … PR-122 (redox-phenytoin) …
Matched Description: … Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one ... has also been investigated for several other indications such as bipolar disorder, retina protection, and ... [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market. …
Matched Salts cas: … 630-93-3
Matched Salts name: … Phenytoin sodium
Matched Categories: … Phenytoin and Prodrugs ... Metabolic Side Effects of Drugs and Substances ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers ... Cytochrome P-450 CYP1A2 Inducers …
Matched Products: … Dilantin-30 Suspension ... DILANTIN CAPSULE 30 mg ... Phenytoin Sodium
NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Investigational
Matched Synonyms: … BENZYL (2S)-2-((((2R,3R,5R)-5-(4-AMINO-2-OXO-PYRIMIDIN-1-YL)-4,4-DIFLUORO-3-HYDROXY-TETRAHYDROFURAN-2 ... -YL)METHOXY-PHENOXY-PHOSPHORYL)AMINO)PROPANOATE ... N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-L-alanine phenylmethyl ester …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … Josamycin propionate
Matched Name: … Josamycin propionate
Matched Iupac: … dimethyl-2-oxo-7-(2-oxoethyl)-10-(propanoyloxy)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino ... (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-(acetyloxy)-5-methoxy-9,16- ... )-5-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate …
Investigational
Matched Synonyms: … )-ethyl]-1H-[1,2,3]triazol-4-ylmethoxy}-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-acetic acid ... ]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]-3,5-diiodophenoxy]-3,5-diiodophenyl]acetic acid ... [4-(4-{1-[2-(2-{2-[2-(2-{2-[2-(4-guanidinomethyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy …
Matched Iupac: … -4-yl)methoxy]-3,5-diiodophenoxy}-3,5-diiodophenyl)acetic acid ... 2-(4-{4-[(1-{20-[4-(carbamimidamidomethyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-yl}-1H-1,2,3-triazol …
Approved
Matched Synonyms: … Phenyl 4-aminosalicylate ... Phenyl PAS ... p-Aminosalol …
Matched Name: … Phenyl aminosalicylate …
Matched Iupac: … phenyl 4-amino-2-hydroxybenzoate …
Matched Categories: … Phenols
Investigational
Matched Synonyms: … O,O'-Bis({4-[3,5-diiodo-4-(1-methylene-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid ... O,O′-Bis({4-[3,5-diiodo-4-(1-methylen-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid ... 2-(4-(4-((1-(107- (4-(fluorophenyl)methoxy)-polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5
Matched Name: … fb-PMT
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Salts cas: … 86393-32-0 …
Matched Mixtures name: … SIPROZONE 500 MG/500 MG FILM KAPLI TABLET,30 ADET ... InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, Lösung ... Ciprofloxacin and Dexamethasone …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... Drug-Related Side Effects and Adverse Reactions ... ciprofloxacin and metronidazole ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% ... CIPROKABI 400 MG/200 ML IV İNFÜZYON ÇÖZELTİSİ, 30 ADET …
Investigational
Matched Synonyms: … 2-tert-butyl-4-chloro-5-((4-((2-(18f)fluoroethoxy)methyl)phenyl)methoxy)pyridazin-3(2h)-one ... 3(2h)-pyridazinone, 4-chloro-2-(1,1-dimethylethyl)-5-((4-((2-(fluoro-18f)ethoxy)methyl)phenyl)methoxy ... 3(2h)-pyridazinone, 4-chloro-2-(1,1-dimethylethyl)-5-((4-((2-(fluoro-(sup 18)f)ethoxy)methyl)phenyl)methoxy …
Matched Categories: … Fluorine Radioisotopes …
Experimental
Matched Synonyms: … bisumth(3+) ion ... bismuth(3+) ... Bismut(III)-ion
Matched Iupac: … bismuth(3+) ion
Approved
Matched Synonyms: … Iron(2+) gluconate (1:2) ... Iron(II) gluconate, anhydrous ... D-gluconic acid, iron(2+) salt (2:1) …
Matched Iupac: … lambda2-iron(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement ... Iron II …
Matched Categories: … Blood and Blood Forming Organs ... ferrous gluconate and folic acid ... Iron Compounds ... Iron Preparations ... Anemia, Iron-Deficiency …
Matched Products: … LOSFERRON FORT EFERVESAN TABLET, 30 ADET ... Iron Dietary Supplement ... Timed Release Iron 35mg …
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Synonyms: … (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone …
Matched Iupac: … 2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-ol …
Matched Description: … Due to the risk of bone fractures that may lead to morbidities and reduced quality of life, the management ... uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation. ... generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System ... Cytochrome P-450 CYP2B6 Inhibitors ... Cytochrome P-450 CYP2C8 Inhibitors …
Matched Products: … PMS-raloxifene …
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … L'acide (benzoyl-3-phenyl)-2-propionique ... 3-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and
Matched Salts cas: … 57495-14-4
Matched Salts name: … Ketoprofen sodium
Matched Categories: … Propionates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP2C9 Inhibitors ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … FENTOP ... MİVELİN PR 200 MG KAPSÜL , 30 ADET ... OKI 3A
Isoliquiritigenin is a precursor to several flavonones in many plants.
Experimental
Matched Synonyms: … (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone ... (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propene-1-one ... 4,2',4'-Trihydroxychalcone …
Matched Iupac: … (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one …
Idronoxil is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called signal transduction inhibitors.
Investigational
Matched Synonyms: … (+/-)-cis-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-3,4-dihydro-2H-cromen-7-ol ... 3-(4-hydroxyphenyl)-2H-chromen-7-ol …
Matched Iupac: … 3-(4-hydroxyphenyl)-2H-chromen-7-ol …
Investigational
Matched Synonyms: … (2s)-2-amino-3-(4-((5-amino-2-phenyl-1,3-benzoxazol-7-yl)methoxy)-3,5-dichloro-phenyl)propanoic acid ... L-tyrosine, o-((5-amino-2-phenyl-7-benzoxazolyl)methyl)-3,5-dichloro- ... O-((5-amino-2-phenyl-1,3-benzoxazol-7-yl)methyl)-3,5- dichloro-l-tyrosine …
Matched Iupac: … (2S)-2-amino-3-{4-[(5-amino-2-phenyl-1,3-benzoxazol-7-yl)methoxy]-3,5-dichlorophenyl}propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Palazestrant is under investigation in clinical trial NCT06016738 (OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer).
Investigational
Matched Synonyms: … (1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1-{4-[(1-propylazetidin-3- yl)oxy]phenyl}-2,3,4,9-tetrahydro ... 1H-Pyrido[3,4-b]indole, 2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-1-[4-[(1-propyl-3-azetidinyl ... )oxy]phenyl]-, (1R,3R)- …
Displaying drugs 551 - 575 of 5671 in total