Displaying drugs 551 - 575 of 2516 in total
Betrixaban
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Synonyms: … N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide ... N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
Matched Description: … Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible ... VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable ... Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism …
Matched Categories: … Blood and Blood Forming Organs ... Hydrocarbons, Cyclic …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
Matched Description: … Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible ... VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable ... Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism …
Matched Categories: … Blood and Blood Forming Organs ... Hydrocarbons, Cyclic …
Sulfacetamide
An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Synonyms: … N-Acetylsulfanilamide ... N-Sulfanilylacetamide ... N-Sulphanilylacetamide …
Matched Iupac: … N-(4-aminobenzenesulfonyl)acetamide …
Matched Description: … An anti-infective agent that is used topically to treat skin infections and orally for urinary tract …
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Plexion NS …
Matched Iupac: … N-(4-aminobenzenesulfonyl)acetamide …
Matched Description: … An anti-infective agent that is used topically to treat skin infections and orally for urinary tract …
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Plexion NS …
Ketotifen
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of ... allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief ... Nu-ketotifen Syrup - 1mg/5ml …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief ... Nu-ketotifen Syrup - 1mg/5ml …
Mecobalamin
Approved
Investigational
Matched Iupac: … dodecamethyl-15,20-dioxo-11,14,16-trioxa-2lambda5,9,19,26,43lambda5,44lambda5,45lambda5-heptaaza-15lambda5-phospha …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Matched Products: … N-cobal 0.5mg film-coated tablet …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Matched Products: … N-cobal 0.5mg film-coated tablet …
AQ-13
AQ-13 is an 4-aminoquinoline analog being investigated for the treatment of malaria.
Investigational
Matched Synonyms: … 1,3-propanediamine, n'-(7-chloro-4-quinolinyl)-n,n-diethyl-, dihydrochloride …
Matched Iupac: … 7-chloro-N-[3-(diethylamino)propyl]quinolin-4-amine dihydrochloride …
Matched Iupac: … 7-chloro-N-[3-(diethylamino)propyl]quinolin-4-amine dihydrochloride …
Binodenoson
Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor. This specificity allows Binodenoson to deliver - in a single injection - a more effective dose of medication with fewer side effects than current treatments, which typically require a...
Investigational
Matched Synonyms: … 2-((Cyclohexylmethylene)hydrazino)adenosine …
Matched Description: … Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Bethanidine
A guanidinium antihypertensive agent that acts by blocking adrenergic transmission.
Approved
Matched Synonyms: … N,N'-dimethyl-N''-(phenylmethyl)-guanidine …
Matched Iupac: … (E)-N'-benzyl-N,N''-dimethylguanidine …
Matched Iupac: … (E)-N'-benzyl-N,N''-dimethylguanidine …
Epsilon-N-methyllysine
Experimental
Matched Synonyms: … N(6)-Methyllysine ... N-Epsilon-methyllysine …
Matched Name: … Epsilon-N-methyllysine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Epsilon-N-methyllysine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lysergic acid diethylamide
Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action of LSD...
Illicit
Investigational
Withdrawn
Matched Synonyms: … N,N-diethyllysergamide ... N,N-diethyl-D-lysergamide ... N,N-diethyl-(+)-lysergamide …
Matched Iupac: … (4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Description: … Debate continues over the nature and causes of chronic flashbacks. ... of LSD on brain chemistry, and varies according to the susceptibility of the individual to the disorder ... Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action …
Matched Categories: … Ergot Alkaloids and Derivatives …
Matched Iupac: … (4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Description: … Debate continues over the nature and causes of chronic flashbacks. ... of LSD on brain chemistry, and varies according to the susceptibility of the individual to the disorder ... Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action …
Matched Categories: … Ergot Alkaloids and Derivatives …
Desmethylsertraline
Desmethylsertraline is a metabolite of sertraline.
Experimental
Matched Synonyms: … N-Demethylsertraline ... N-Desmethylsertraline …
Matched Categories: … Hydrocarbons, Cyclic …
Matched Categories: … Hydrocarbons, Cyclic …
Diethylnorspermine
Investigational
Matched Synonyms: … N1,N11-Diethylnorspermine ... N(1),N(11)-Diethylnorspermine ... 1,3-PROPANEDIAMINE, N,N'-BIS(3-(ETHYLAMINO)PROPYL)- …
Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …
Matched Products: … Cefotaxime and Dextrose …
Sodium bicarbonate
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Description: … powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and …
Matched Mixtures name: … Quality Choice Effervescent Antacid and Pain Relief ... Quality Choice Extra Strength Effervescent Antacid and Pain Relief ... Gavilyte-N …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …
Matched Mixtures name: … Quality Choice Effervescent Antacid and Pain Relief ... Quality Choice Extra Strength Effervescent Antacid and Pain Relief ... Gavilyte-N …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …
Cyclizine
A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)
Approved
Matched Synonyms: … (N-Benzhydryl)(N'-methyl)diethylenediamine ... N-Benzhydryl-N'-methylpiperazine ... N-methyl-N'-benzhydrylpiperazine …
Matched Description: … vomiting and in motion sickness. ... A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced …
Matched Description: … vomiting and in motion sickness. ... A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced …
(R)-N-methyl-N-2-propynyl-1-indanamine
Experimental
Matched Synonyms: … N-Methyl-N-propargyl-1(R)-aminoindan …
Matched Name: … (R)-N-methyl-N-2-propynyl-1-indanamine …
Matched Iupac: … (1R)-N-methyl-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine …
Matched Name: … (R)-N-methyl-N-2-propynyl-1-indanamine …
Matched Iupac: … (1R)-N-methyl-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine …
Betamethasone phosphate
Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Synonyms: … Betamethasone 21-phosphate ... Betamethasone dihydrogen phosphate ... Betamethasone 21-(dihydrogen phosphate) …
Matched Name: … Betamethasone phosphate …
Matched Description: … L11994] Betamethasone provides greater anti-inflammatory activity than [prednisolone] with less sodium and ... [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994] ... Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Betamethasone phosphate …
Matched Description: … L11994] Betamethasone provides greater anti-inflammatory activity than [prednisolone] with less sodium and ... [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994] ... Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Evenamide
Investigational
Matched Synonyms: … 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethylacetamide ... Acetamide, 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethyl- …
Alverine
Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Approved
Investigational
Matched Synonyms: … N,N-Bis(3-phenylpropyl)ethylamine ... N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine ... N-Ethyl-N-(3-phenylpropyl)benzenepropanamine …
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. ... It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. ... It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. …
Matched Categories: … Alimentary Tract and Metabolism …
Magnesium phosphate
Experimental
Matched Synonyms: … Magnesium phosphate (3:2) ... Trimagnesium phosphate ... Magnesium phosphate anhydrous …
Matched Name: … Magnesium phosphate …
Matched Salts name: … Magnesium phosphate pentahydrate ... Magnesium phosphate dibasic trihydrate …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... magnesium phosphate …
Matched Name: … Magnesium phosphate …
Matched Salts name: … Magnesium phosphate pentahydrate ... Magnesium phosphate dibasic trihydrate …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... magnesium phosphate …
Levomefolic acid
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Synonyms: … N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic …
Matched Description: … and regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the ... blood-brain barrier into various tissues where it plays an essential role in the DNA synthesis, cysteine cycle …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... L-Methyl MC NAC ... L-Methyl-MC-NAC …
Matched Salts name: … Levomefolate calcium …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins …
Matched Products: … L-Methylfolate Calcium …
Matched Description: … and regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the ... blood-brain barrier into various tissues where it plays an essential role in the DNA synthesis, cysteine cycle …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... L-Methyl MC NAC ... L-Methyl-MC-NAC …
Matched Salts name: … Levomefolate calcium …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins …
Matched Products: … L-Methylfolate Calcium …
Echothiophate
A potent, long-acting irreversible cholinesterase inhibitor used as an ocular hypertensive in the treatment of glaucoma. Occasionally used for accomodative esotropia.
Approved
Matched Synonyms: … 2-(Diethoxyphosphorylsulfanyl)ethyl-N,N,N-trimethylazanium iodide …
Matched Iupac: … diethyl {[2-(trimethylazaniumyl)ethyl]sulfanyl}phosphonate …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Iupac: … diethyl {[2-(trimethylazaniumyl)ethyl]sulfanyl}phosphonate …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Creatine
An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … N-methyl-N-guanylglycine ... N-carbamimidoyl-N-methylglycine ... N-(aminoiminomethyl)-N-methylglycine …
Matched Iupac: … 2-(N-methylcarbamimidamido)acetic acid …
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … 2-(N-methylcarbamimidamido)acetic acid …
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Fosdenopterin
Molybdenum cofactor deficiency (MoCD) is an exceptionally rare autosomal recessive disorder resulting in a deficiency of three molybdenum-dependent enzymes: sulfite oxidase (SOX), xanthine dehydrogenase, and aldehyde oxidase. Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites resulting from a lack of SOX activity.[A230088,L32163]...
Approved
Matched Synonyms: … Cyclic pyranopterin monophosphate …
Matched Description: … wherein the first step of molybdenum cofactor synthesis - the conversion of guanosine triphosphate into cyclic ... [A230088] Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites ... paraplegia, myoclonus, and opisthotonus. …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Cyclic Pyranopterin Monophosphate …
Matched Description: … wherein the first step of molybdenum cofactor synthesis - the conversion of guanosine triphosphate into cyclic ... [A230088] Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites ... paraplegia, myoclonus, and opisthotonus. …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Cyclic Pyranopterin Monophosphate …
Miglustat
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Synonyms: … N-(n-Butyl)deoxynojirimycin ... NB-DNJ ... N-Butylmoranoline …
Matched Description: … Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... patients in the European Union, Brazil, and South Korea. ... It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Description: … Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... patients in the European Union, Brazil, and South Korea. ... It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Displaying drugs 551 - 575 of 2516 in total