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Displaying drugs 551 - 575 of 3142 in total

Azelastine

Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Categories: … Anti-Allergic Agents …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Categories: … Anti-Anxiety Agents …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Categories: … Anti-Ulcer Agents …

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Categories: … Anti-Infective Agents …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Categories: … Anti-Infective Agents …

Anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Name: … Anti-inhibitor coagulant complex …
Matched Description: … Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains …

Natalizumab

Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … Anti-VLA4 ... Anti-alpha4 integrin ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE …

Idecabtagene vicleucel

Multiple myeloma is a cancer where plasma cells rapidly divide out of control. These cancerous cells generally express the B-cell maturation antigen, while it is rarely expressed on non-cancerous cells. Multiple myeloma is typically treated with an immunomodulatory agent like lenalidomide, a proteasome inhibitor like bortezomib, or an anti-CD38 monoclonal...
Approved
Matched Synonyms: … Anti-BCMA CAR T cell …
Matched Description: … [A232558] The chimeric antigen receptor of idecabtagene vicleucel includes an anti-B-cell maturation ... immunomodulatory agent like [lenalidomide],[A232593] a proteasome inhibitor like [bortezomib], or an anti-CD38 …

Tarlatamab

Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …

Axicabtagene ciloleucel

Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Matched Synonyms: … Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen …
Matched Description: … Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. ... [A216163] Once T-cells are collected from the patient, they are genetically engineered to express anti-CD19 ... of researchers at the National Cancer Institute (NCI), who demonstrated that T cells expressing an anti-CD19 …

Spesolimab

Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain) …

Tolnaftate

Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Description: … Tolnaftate is a synthetic over-the-counter anti-fungal agent. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Categories: … Anti-Infective Agents …
Matched Products: … Jock Itch ... Jock Itch Relief ... Good Sense Jock Itch …

Peppermint oil

Extracted from the stem, leaves, and flowers of Mentha piperita L. plant, peppermint oil (Mentha piperita) is a popular essential oil used in aromatherapy for both external and internal use. Mentha piperita is a hybrid of spearmint (Mentha spicata) and water mint (Mentha aquatica) . Medicinal use of herbal ingredients...
Approved
Investigational
Matched Description: … oil is used as a flavouring agent in foods and fragrance in hygienic or cosmetic products, and as an anti-itch …
Matched Products: … Anti Itch Balm ... Anti-Bacterial Sticker …

Miconazole

Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Categories: … Anti-Infective Agents …
Matched Products: … Jock Itch ... Anti-Fungal ... Jock Itch Relief …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Mixtures name: … Terrasil Rapid-Clear Anti-Fungal ... Terrasil Rapid-Clear Anti-Fungal …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local …
Matched Products: … Jock Itch ... Equate Jock Itch ... Walgreens Jock Itch …

Pucotenlimab

Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus …
Matched Description: … Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. …

Camphor

Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Description: … It is used topically as a skin antipruritic and as an anti-infective agent. …
Matched Mixtures name: … Earths Care Anti-itch ... Earths Care Anti-Itch ... Winlykah Anti- Itch Cream …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local …
Matched Products: … Band-aid Brand Anti-itch Gel ... Band-aid Brand Anti-itch Spray …

Aluminum acetate

Approved
Investigational
Matched Products: … Dermeleve Anti Itch Scalp Serum …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. …
Matched Mixtures name: … Lanacane Anti Itch Maximum Strength ... Lanacane Anti Itch Original Strength ... Lanacane Anti Itch Original Strength …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local ... Miscellaneous Local Anti-infectives …
Matched Products: … Clean Revolution Anti-Bacterial Hand Refill Supply Container - Anti-Bacterial - ELIMINATES 99.9% Germs ... Clean Revolution Anti-Bacterial Foaming Hand Refill Supply Container - Anti-Bacterial - ELIMINATES 99.9% ... Candy Apple Anti Bacterial Hand Sanitizer …

Ketotifen

Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Categories: … Anti-Allergic Agents ... Anti-Asthmatic Agents …
Matched Products: … Eye Itch ... Eye Itch Relief ... Eye Itch Releif …

Butenafine

Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Approved
Matched Categories: … Anti-Infective Agents …
Matched Products: … Jock Itch ... Lotrimin Ultra Jock Itch ... Lotrimin Ultra Jock Itch Antifungal …

Menthol

Approved
Matched Mixtures name: … Anti-Itch ... Anti-Itch ... Anti-Itch …
Matched Products: … Anti Itch ... Moisture Therapy Anti-Itch ... Phoenix KinetiCream Anti-inflammatory and Pain Relief …

Zinc acetate

Approved
Investigational
Matched Mixtures name: … Anti-Itch ... Anti-Itch ... Anti Itch Cream …

Resorcinol

Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works...
Approved
Matched Description: … is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal …
Matched Mixtures name: … Anti Itch ... Budpak Feminine Anti-Itch ... Assured Feminine Anti-itch …
Matched Categories: … Anti-Acne Preparations ... Anti-Infective Agents ... Anti-Infective Agents, Local ... Anti-Acne Preparations for Topical Use …

Bemiparin

Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Description: … These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and …
Matched Products: … Ivor 2500 IE Anti-Xa/0,2 ml Injektionslösung in Fertigspritzen ... Ivor 3500 IE Anti-Xa/0,2 ml Injektionslösung in Fertigspritzen ... Ivorat 25.000 IE Anti-Xa/ml - Injektionslösung in Fertigspritzen …
Displaying drugs 551 - 575 of 3142 in total