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Displaying drugs 576 - 600 of 791 in total
Experimental
Investigational
Matched Synonyms: … Methyl sulfone
Matched Name: … Dimethyl sulfone
Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated for the treatment of Hunter syndrome.
Investigational
Matched Synonyms: … DNL-310, recombinant iduronate 2-sulfatase
Rumex crispus top allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Rumex crispus flower/leaf/stem extract …
Investigational
Matched Synonyms: … Monoclonal antibody targeting CCL24 ... Monoclonal antibody targeting eotaxin-2 …
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Synonyms: … Bithionol sulfide ... 2-Hydroxy-3,5-dichlorophenyl sulfide ... Bis(3,5-dichloro-2-hydroxyphenyl) sulfide
Matched Description: … Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Experimental
Matched Synonyms: … CC49 monoclonal antibody ... Monoclonal antibody CC49 …
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Synonyms: … 4-aminophenyl sulfone ... p-aminophenyl sulfone ... bis(4-aminophenyl)sulfone
Matched Description: … A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium …
Matched Categories: … dapsone and rifampicin ... dapsone, rifampicin and clofazimine …
Naxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside.[L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and within...
Approved
Matched Synonyms: … Monoclonal antibody HU3F8 ... Anti-Gd2 monoclonal antibody 3F8 humanized ... Humanized monoclonal antibody HU3F8-IGG1 …
Matched Description: … [L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and ... within neuroblastomas (and other neuroectodermal tumors),[A224609] and is rarely subject to antigen ... constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Glycolipid Disialoganglioside-directed Antibody ... Glycolipid Disialoganglioside-directed Antibody Interactions …
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …
Investigational
Matched Synonyms: … Monoclonal antibody PM-81 ... Anti-CD15 monoclonal antibody PM-81 ... Anti-AML/SCCL-trigger monoclonal antibody
Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy in Treating Patients With Neuroblastoma That Has Not Responded to Previous Treatment).
Investigational
Matched Synonyms: … MONOCLONAL ANTIBODY 3F8 ... ANTI-GD2 MOUSE MONOCLONAL ANTIBODY 3F8 (IGG3) …
Matched Name: … Anti-GD2 monoclonal antibody 3F8 …
Matched Description: … Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy …
Epimedium grandiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Epimedium Grandiflorum Leaf/stem …
A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Investigational
Matched Name: … anti-OX40 antibody BMS 986178 …
Matched Description: … A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 ... antibody. …
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Synonyms: … 2C4 Antibody ... Monoclonal Antibody 2C4 …
Matched Description: … It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. ... It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents …
BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed by Bliss Biopharmaceutical.
Investigational
Matched Synonyms: … Humanized IgG1kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin …
Matched Description: … BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed …
Ocimum tenuiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Holy Basil Leaf/stem …
Experimental
Matched Synonyms: … Thin-leaf polygala root …
A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.
Investigational
Nutraceutical
Matched International brands: … Tona-lean 1000 CLA …
Matched Description: … A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. …
Investigational
Matched Synonyms: … anti-Cd33 monoclonal antibody BI 836858 ... Fully Human Igg1 Antibody Specific For Cd33 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … Methyl Methylsulfinylmethyl Sulfide
Olitigaltin has been investigated for the treatment of Idiopathic Pulmonary Fibrosis.
Investigational
Matched Synonyms: … Bis-(3-deoxy-3-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-B-D-galactopyranosyl) sulfane
Experimental
Matched Synonyms: … Methionine sulfone
Matched Name: … L-methionine sulfone
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused ... with human iduronate-2-sulfatase, glycoform alfa: ... ) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN IDURONATE-2-SULFATASE
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Synonyms: … 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate ... 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate
Matched Iupac: … [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... , and 40% of its mass accounted for by oxygen. ... distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Synonyms: … Hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-Dfructofuranosyl-α-D-glucopyranoside tetrakis(hydrogen sulfato
Matched Description: … It is sold under many brands and is available in both tablet and suspension forms. ... Sucralfate has been shown to be a well-tolerated and safe drug. ... Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Sulcrate ... Sulcrate Sus 100mg/ml ... Sulcrate Suspension Plus …
Displaying drugs 576 - 600 of 791 in total