Displaying drugs 576 - 600 of 2580 in total
Fumaric acid
Investigational
Matched Synonyms: … Fumaric acid ... Fumaricum acidum ... (2E)-2-butenedioic acid …
Matched Name: … Fumaric acid …
Matched Iupac: … (2E)-but-2-enedioic acid …
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Fumaric acid …
Matched Iupac: … (2E)-but-2-enedioic acid …
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids …
Vudalimab
Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and …
Atuliflapon
Atuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-severe Uncontrolled Asthma).
Investigational
Matched Synonyms: … (1r,2r)-2-(4-(3-methyl-1h-pyrazol-5-yl)benzoyl)-n-(4-oxo-6,7-dihydro-5h-pyrazolo(1,5-a)pyrazine-3-yl) ... Cyclohexanecarboxamide, 2-(4-(5-methyl-1h-pyrazol-3-yl)benzoyl)-n-(4,5,6,7-tetrahydro-4-oxopyrazolo(1,5 …
Matched Description: … Atuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety …
Matched Description: … Atuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety …
Pentosan polysulfate
Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Approved
Matched Synonyms: … Pentosan sulfuric polyester …
Matched Iupac: … hydroxy-2-{[(3R,4S,5R,6R)-6-hydroxy-4,5-bis(sulfooxy)oxan-3-yl]oxy}-4-(sulfooxy)oxan-3-yl]oxidanesulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfuric Acids ... Genito Urinary System and Sex Hormones ... Sulfur Compounds …
Matched Iupac: … hydroxy-2-{[(3R,4S,5R,6R)-6-hydroxy-4,5-bis(sulfooxy)oxan-3-yl]oxy}-4-(sulfooxy)oxan-3-yl]oxidanesulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfuric Acids ... Genito Urinary System and Sex Hormones ... Sulfur Compounds …
Ritodrine
Adrenergic beta-agonist used to control premature labor.
Approved
Investigational
Matched Synonyms: … p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcohol …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Categories: … Genito Urinary System and Sex Hormones …
Tolterodine
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Synonyms: … (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol …
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID
Experimental
Matched Name: … 5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID …
Matched Iupac: … 2-benzenesulfonamido-5-methylbenzoic acid …
Matched Iupac: … 2-benzenesulfonamido-5-methylbenzoic acid …
4-(Acetylamino)-3-[(Aminoacetyl)Amino]Benzoic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-[(Aminoacetyl)Amino]Benzoic Acid …
1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
Experimental
Matched Name: … 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid …
Matched Iupac: … (2R,3R,4S)-2,4-dihydroxy-3-(sulfooxy)-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Iupac: … (2R,3R,4S)-2,4-dihydroxy-3-(sulfooxy)-3,4-dihydro-2H-pyran-6-carboxylic acid …
PLX51107
PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family.[A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin …
Matched Iupac: … 4-[6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic acid …
Matched Description: … PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family ... [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine …
Matched Iupac: … 4-[6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic acid …
Matched Description: … PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family ... [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine …
Denifanstat
Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. Due to its antineoplastic activities, it is being investigated for various cancers.
Investigational
Matched Synonyms: … Benzonitrile, 4-(1-(4-cyclobutyl-2-methyl-5-(3-methyl-1h-1,2,4-triazol-5-yl)benzoyl)-4-piperidinyl)- …
Matched Iupac: … 4-{1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl}benzonitrile …
Matched Description: … Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. …
Matched Iupac: … 4-{1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl}benzonitrile …
Matched Description: … Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. …
Bendroflumethiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... bendroflumethiazide and potassium ... Gynecological Antiinfectives and Antiseptics ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... bendroflumethiazide and potassium ... Gynecological Antiinfectives and Antiseptics ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Benzo[B]Thiophene-2-Boronic Acid
Experimental
Matched Name: … Benzo[B]Thiophene-2-Boronic Acid …
Matched Iupac: … (1-benzothiophen-2-yl)boronic acid …
Matched Iupac: … (1-benzothiophen-2-yl)boronic acid …
Clavulanic acid
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … Clavulanic acid ... Acide clavulanique ... Acidum clavulanicum …
Matched Name: … Clavulanic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA ACIDO CLAVULANICO TEVA ... AMOXICILLINA ACIDO CLAVULANICO TEVA …
Matched Name: … Clavulanic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA ACIDO CLAVULANICO TEVA ... AMOXICILLINA ACIDO CLAVULANICO TEVA …
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Etidronic acid
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid …
Hydrochlorothiazide
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459]
Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting …
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and HCTZ …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and HCTZ …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …
Telitacicept
Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
4-(Hydrogen sulfate)-beta-D-galactopyranose
Experimental
Matched Synonyms: … 4-O-Sulfo-β-D-galactopyranose …
Matched Iupac: … [(2R,3R,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxidanesulfonic acid …
Matched Iupac: … [(2R,3R,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxidanesulfonic acid …
TH-9402 free base
Investigational
Matched Synonyms: … Benzoic acid, 2-(6-amino-4,5-dibromo-3-imino-3h-xanthen-9-yl)-, methyl ester …
Heparin
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Synonyms: … Heparinic acid …
Matched Description: … coagulation enzymes thrombin (factor IIa) and factor Xa. ... UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
Matched Description: … coagulation enzymes thrombin (factor IIa) and factor Xa. ... UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
4-(Acetylamino)-3-[(Hydroxyacetyl)Amino]Benzoic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-[(Hydroxyacetyl)Amino]Benzoic Acid …
Matched Iupac: … 4-acetamido-3-(2-hydroxyacetamido)benzoic acid …
Matched Iupac: … 4-acetamido-3-(2-hydroxyacetamido)benzoic acid …
2-{[(4-CHLOROPHENOXY)ACETYL]AMINO}BENZOIC ACID
Experimental
Matched Name: … 2-{[(4-CHLOROPHENOXY)ACETYL]AMINO}BENZOIC ACID …
Matched Iupac: … 2-[2-(4-chlorophenoxy)acetamido]benzoic acid …
Matched Iupac: … 2-[2-(4-chlorophenoxy)acetamido]benzoic acid …
PARPI F-18
PARPI F-18 is a diagnostic agent under investigation for use in the management of glioblastoma multiforme.
Investigational
Matched Synonyms: … 1(2h)-phthalazinone, 4-((4-fluoro-3-((4-(4-(fluoro-18f)benzoyl)-1-piperazinyl)carbonyl)phenyl)methyl) …
Idasanutlin
Idasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.
Investigational
Matched Synonyms: … BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2 …
Matched Iupac: … fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid …
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid …
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Displaying drugs 576 - 600 of 2580 in total