Displaying drugs 601 - 625 of 3248 in total
Dichlorvos
Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. The compound has been available on the market since 1961 and its use is a controversial topic...
Vet approved
Matched Synonyms: … 2,2-Dichloroethenyl dimethyl phosphate ... Dimethyl 2,2-dichlorovinyl phosphate ... Dimethyl-2,2-dichlorovinyl phosphate …
Matched Iupac: … 2,2-dichloroethenyl dimethyl phosphate …
Matched Description: … Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the _organophosphate_ class, frequently ... , and cancer. ... environmental and health concerns. …
Matched Iupac: … 2,2-dichloroethenyl dimethyl phosphate …
Matched Description: … Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the _organophosphate_ class, frequently ... , and cancer. ... environmental and health concerns. …
Etevritamab
Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND ... Anti-egfrviii/cd3 bite antibody amg 596 …
Fazpilodemab
Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and …
PD-169316
PD-169316 is a p38 MAP kinase inhibitor.
Investigational
Matched Synonyms: … Pyridine, 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-5-yl)- ... Pyridine, 4-(5-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-4-yl)- ... 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1h-imidazole …
Matched Iupac: … 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine …
Matched Iupac: … 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine …
D-glyceraldehyde 3-phosphate
An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
Experimental
Matched Synonyms: … Glyceraldehyde-3-phosphate ... D-Glyceraldehyde 3-phosphate …
Matched Name: … D-glyceraldehyde 3-phosphate …
Matched Description: … An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. …
Matched Name: … D-glyceraldehyde 3-phosphate …
Matched Description: … An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. …
Pyridoxamine
Pyridoxamine has been used in trials studying the treatment of Kidney Stones.
Investigational
Matched Name: … Pyridoxamine …
Matched Iupac: … 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Description: … Pyridoxamine has been used in trials studying the treatment of Kidney Stones. …
Matched Salts name: … Pyridoxamine phosphate ... Pyridoxamine hydrochloride …
Matched Iupac: … 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Description: … Pyridoxamine has been used in trials studying the treatment of Kidney Stones. …
Matched Salts name: … Pyridoxamine phosphate ... Pyridoxamine hydrochloride …
Loxapine
An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Salts name: … Loxapine hydrochloride …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … Loxapine Hydrochloride Im Injection 50mg/ml ... Loxapine Hydrochloride Oral Concentrate 25mg/ml ... Loxapine-5 …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … Loxapine Hydrochloride Im Injection 50mg/ml ... Loxapine Hydrochloride Oral Concentrate 25mg/ml ... Loxapine-5 …
Fructose-6-phosphate
Experimental
Matched Synonyms: … D-Fructose 6-phosphate ... keto-D-fructose 6-phosphate …
Matched Name: … Fructose-6-phosphate …
Matched Iupac: … {[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl]oxy}phosphonic acid …
Matched Categories: … Sugar Phosphates …
Matched Name: … Fructose-6-phosphate …
Matched Iupac: … {[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl]oxy}phosphonic acid …
Matched Categories: … Sugar Phosphates …
1'-Deazo-Thiamin Diphosphate
Experimental
Matched Name: … 1'-Deazo-Thiamin Diphosphate …
Matched Iupac: … 3-[(2-amino-6-methylpyridin-3-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy}ethyl …
Matched Iupac: … 3-[(2-amino-6-methylpyridin-3-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy}ethyl …
Estramustine phosphate
A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Approved
Investigational
Matched Synonyms: … Estramustine 17-(dihydrogen phosphate) …
Matched Name: … Estramustine phosphate …
Matched Iupac: … {[(1S,3aS,3bR,9bS,11aS)-7-{[bis(2-chloroethyl)carbamoyl]oxy}-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H …
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …
Matched Name: … Estramustine phosphate …
Matched Iupac: … {[(1S,3aS,3bR,9bS,11aS)-7-{[bis(2-chloroethyl)carbamoyl]oxy}-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H …
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …
Cariprazine
Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. Cariprazine has been investigated in a variety of psychiatric disorders,...
Approved
Investigational
Matched Synonyms: … trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochloride …
Matched Description: … receptors and as an antagonist at serotonin 5-HT2A receptors. ... [A247100] It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A ... [L41670] It is currently used to treat schizophrenia, and manic or mixed episodes and depressive episodes …
Matched Salts name: … Cariprazine hydrochloride …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Description: … receptors and as an antagonist at serotonin 5-HT2A receptors. ... [A247100] It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A ... [L41670] It is currently used to treat schizophrenia, and manic or mixed episodes and depressive episodes …
Matched Salts name: … Cariprazine hydrochloride …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … α-D-ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) ... 5-Phosphoribosyl diphosphate ... 5-Phosphoribosyl 1-pyrophosphate …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Matched Categories: … Sugar Phosphates …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Matched Categories: … Sugar Phosphates …
Granisetron
A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Iupac: … 1-methyl-N-[(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1H-indazole-3-carboxamide …
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Matched Salts name: … Granisetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Serotonin 5-HT3 Receptor Antagonists ... Antiemetic Serotonin 5-HT3 Receptor Antagonists …
Matched Products: … Granisetron Hydrochloride ... Granisetron hydrochloride ... GRANISETRON HYDROCHLORIDE …
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Matched Salts name: … Granisetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Serotonin 5-HT3 Receptor Antagonists ... Antiemetic Serotonin 5-HT3 Receptor Antagonists …
Matched Products: … Granisetron Hydrochloride ... Granisetron hydrochloride ... GRANISETRON HYDROCHLORIDE …
Topotecan
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Salts cas: … 119413-54-6 …
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... TOPOTU 4MG/4ML KONSANTRE INFÜZYON ÇÖZELTISI, 5 FLAKON ... Topotecan Hydrochloride …
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... TOPOTU 4MG/4ML KONSANTRE INFÜZYON ÇÖZELTISI, 5 FLAKON ... Topotecan Hydrochloride …
Citicoline
Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Approved
Experimental
Matched Synonyms: … Cytidine 5'-diphosphocholine ... Cytidine-5'-diphosphocholine ... Cytidine 5'-(choline diphosphate) …
Matched Iupac: … {2-[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … , Cocaine Abuse, and Bipolar Disorder, among others. ... It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM ... NEUROLIN 500 ... RONOCIT 500 MG/4 ML I.M./I.V. AMPUL ,AMPUL, 5 ADET …
Matched Iupac: … {2-[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … , Cocaine Abuse, and Bipolar Disorder, among others. ... It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM ... NEUROLIN 500 ... RONOCIT 500 MG/4 ML I.M./I.V. AMPUL ,AMPUL, 5 ADET …
Procaine
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. …
Matched Salts cas: … 51-05-8 …
Matched Salts name: … Procaine phosphate ... Procaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Procaine Hydrochloride ... NTCAIN 50 MG/5 ML IM AMPUL , 50 ADET ... NTCAIN 50 MG/5 ML IM AMPUL , 10 ADET …
Matched Salts cas: … 51-05-8 …
Matched Salts name: … Procaine phosphate ... Procaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Procaine Hydrochloride ... NTCAIN 50 MG/5 ML IM AMPUL , 50 ADET ... NTCAIN 50 MG/5 ML IM AMPUL , 10 ADET …
Thiamphenicol
Experimental
Investigational
Matched Products: … THIAMIKA ... URFEKOL 500 ... GENICOL-500 …
Avoralstat
Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.
Investigational
Matched Synonyms: … 3-(2-((4-Carbamimidoylphenyl)carbamoyl)-4-ethenyl-5-methoxyphenyl)-6-((cyclopropylmethyl)carbamoyl)pyridine ... 3-[2-(4-carbamimidoyl-phenylcarbamoyl)-5-methoxy-4-vinyl-phenyl]-6-(cyclopropylmethyl-carbamoyl)-pyridine ... 3-[2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl]-6-(cyclopropylmethylcarbamoyl)pyridine …
Matched Iupac: … 3-{2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl}-6-[(cyclopropylmethyl)carbamoyl]pyridine …
Matched Description: … Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema. …
Matched Iupac: … 3-{2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl}-6-[(cyclopropylmethyl)carbamoyl]pyridine …
Matched Description: … Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema. …
AZD2066
Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Categories: … Receptor, Metabotropic Glutamate 5, antagonists & inhibitors …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Categories: … Receptor, Metabotropic Glutamate 5, antagonists & inhibitors …
Hydroxyzine
Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched International brands: … Vistaject-50 …
Matched Description: … piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and ... for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
Matched Description: … piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and ... for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
Methotrexate
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Description: … Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and …
Matched Salts cas: … 7413-34-5 …
Matched Salts name: … Methotrexate sodium …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Methotrexate Sodium ... Ratio-methotrexate Sodium ... Methotrexate Sodium Inj 20mg …
Matched Salts cas: … 7413-34-5 …
Matched Salts name: … Methotrexate sodium …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Methotrexate Sodium ... Ratio-methotrexate Sodium ... Methotrexate Sodium Inj 20mg …
Doxapram
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched Salts cas: … 7081-53-0 …
Matched Salts name: … Doxapram hydrochloride …
Matched Products: … Doxapram Hydrochloride ... RESDOX 20 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …
Matched Salts name: … Doxapram hydrochloride …
Matched Products: … Doxapram Hydrochloride ... RESDOX 20 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …
Chlorpromazine
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Description: … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the …
Matched Salts name: … Chlorpromazine hydrochloride …
Matched Categories: … Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Matched Products: … CHLORPROMAZINE HYDROCHLORIDE TABLET 50 mg ... Chlorpromazine Hydrochloride ... โปเกตอล 50 …
Matched Salts name: … Chlorpromazine hydrochloride …
Matched Categories: … Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Matched Products: … CHLORPROMAZINE HYDROCHLORIDE TABLET 50 mg ... Chlorpromazine Hydrochloride ... โปเกตอล 50 …
Quinapril
Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure.[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Quinapril was granted FDA approval...
Approved
Investigational
Matched Description: … [L8420,L8423] It is used to treat hypertension and heart failure. ... ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide …
Matched Salts cas: … 82586-55-8 …
Matched Mixtures name: … Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Quinapril Hydrochloride …
Matched Categories: … ACE Inhibitors and Diuretics ... quinapril and diuretics …
Matched Products: … Quinapril Hydrochloride ... ACCUPRO 5MG ... แอคคูพริล (5มก) …
Matched Salts cas: … 82586-55-8 …
Matched Mixtures name: … Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Quinapril Hydrochloride …
Matched Categories: … ACE Inhibitors and Diuretics ... quinapril and diuretics …
Matched Products: … Quinapril Hydrochloride ... ACCUPRO 5MG ... แอคคูพริล (5มก) …
Displaying drugs 601 - 625 of 3248 in total