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Displaying drugs 651 - 675 of 918 in total

Erlotinib

Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the trade name Tarceva. Erlotinib binds to the epidermal growth factor receptor (EGFR)...
Approved
Investigational
Matched Description: … EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and ... , which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and ... This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TARCEVA FILM-COATED TABLET 25 MG ... TARCEVA FILM-COATED TABLET 100 MG ... TARCEVA FILM-COATED TABLET 150 MG …

Zofenopril

Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Approved
Matched Description: … Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. …
Matched Mixtures name: … BIFRIL PLUS 30/12.5 MG FILM TABLET, 28 ADET ... BIFRIL PLUS 30/12.5 MG FILM TABLET, 84 ADET ... ZOPROTEC PLUS 30/12.5 MG FILM TABLET, 28 ADET …
Matched Categories: … ACE Inhibitors and Diuretics ... zofenopril and diuretics ... zofenopril and nebivolol ... Amino Acids, Peptides, and Proteins …
Matched Products: … BIFRIL 15 MG (FILM-COATED TABLETS) ... BIFRIL 30 MG (FILM-COATED TABLETS) ... BIFRIL 30 MG FILM TABLET, 14 ADET …

Gefitinib

Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … VEIASU FILM-COATED TABLETS 250 MG ... Iressa 250mg Film-coated Tablet ... GEFTINAT FILM COATED TABLETS 250 MG …

Lornoxicam

Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
Approved
Investigational
Matched Description: … new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … XEFO 4 MG FILM KAPLI TABLET, 20 ADET ... XEFO RAPID 8 MG FILM KAPLI TABLET ... XEFO 8 MG FILM KAPLI TABLET, 20 ADET …

Valaciclovir

Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Description: … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and ... It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. ... This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 …
Matched Categories: … Acyclovir and prodrug ... Amino Acids, Peptides, and Proteins ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … VIROMED 500 MG FILM TABLET,10 ADET ... VIROMED 500 MG FILM TABLET,42 ADET ... VIROMED 1000 MG FILM TABLET,21 TABLET …

Benidipine

Benidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently available in some Asian countries like India and Japan.[L1385, L1386]
Experimental
Matched Description: … available in some Asian countries like India and Japan. ... It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. ... [A31948] It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … BENIPIN 4 MG FILM TABLET,TABLET, 30 ADET ... BENIPIN 8 MG FILM TABLET,TABLET, 30 ADET ... BENİTİDE 4 MG FİLM KAPLI TABLET, 30 ADET …

Olaparib

Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Description: … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Lynparza 150 mg Film-Coated Tablets ... Lynparza 100 mg Film-Coated Tablets ... LYNPARZA FILM-COATED TABLET 150MG …

Empagliflozin

Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. The first known inhibitor...
Approved
Matched Description: … led to the FDA approval of [canagliflozin] in 2013 and both [dapagliflozin] and empagliflozin in 2014 ... the first and only approved treatment in Europe and Canada for adults with symptomatic chronic heart ... [A203453] It is used clinically as an adjunct to diet and exercise, often in combination with other drug …
Matched Mixtures name: … Glyxambi Film-Coated Tablets 25mg/5mg ... Glyxambi Film-Coated Tablets 10mg/5mg ... GLYXAMBI FILM-COATED TABLETS 25 MG/5 MG …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and empagliflozin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin …
Matched Products: … JARDIANCE FILM-COATED TABLETS 10MG ... JARDIANCE FILM-COATED TABLET 25MG ... Jardiance 10mg film coated tablets …

Prucalopride

Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Matched Description: … A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018. ... dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and ... [A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[ …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … RESOLOR 1mg Film Coated Tablets ... RESOLOR 2mg Film Coated Tablets ... Resolor Film-coated Tablet 2 mg …

Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Mixtures name: … FEMARİS PLUS 150 MG/5600 IU FİLM KAPLI TABLET, 3 ADET …
Matched Categories: … Calcium-Regulating Hormones and Agents ... risedronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential …
Matched Products: … ACTEDAY 5 MG FİLM TABLET, 28 ADET ... BONEPLUS 5 MG FİLM TABLET, 28 ADET ... INDRONATE FILM-COATED TABLET 35 MG …

Ebastine

Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Approved
Investigational
Matched Products: … Kestine 10mg film-coated tablets ... Kestine 20mg film-coated tablets ... KESTINE FILM-COATED TABLET 20MG …

Bacampicillin

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Description: … It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract ... Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. ... and acute uncomplicated gonococcal urethritis etc. …
Matched Products: … İEBAK 400 MG FILM TABLET 10 ADET ... İEBAK 800 MG FILM TABLET 10 ADET ... SANOSİLİN 400 MG FİLM TABLET, 10 TABLET …

Roflumilast

Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells like those of the smooth muscle or epithelium. The resultant increase in intracellular cAMP induced by roflumilast's inhibition of PDE4...
Approved
Matched Description: … adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and ... [L46546] It was first approved by the EMA in July 2010, and by the FDA in January 2018. ... The cream formulation was first approved by the FDA in July 2022 [L42580] and by Health Canada in April …
Matched Products: … DAXAS 500 MCG FILM-COATED TABLETS ... DAXAS 500 MCG FILM TABLET, 30 ADET ... DAXAS 500 MCG FILM TABLET, 90 ADET …

Ribavirin

Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Description: … The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks ... in patients with genotype 2 and 3 [A19626]. ... infection and 70% in patients with genotype 2-6. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Copegus film coated tablet 200mg ... VIRON 400 MG FİLM KAPLI TABLET, 56 ADET ... VİRANİS 200 MG FİLM TABLET, 70 ADET …

Rosuvastatin

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... studies to significantly reduce the risk of development of CVD and all-cause mortality. ... of metabolic reactions involved in the production of several compounds involved in lipid metabolism and …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … Alimentary Tract and Metabolism ... rosuvastatin and valsartan ... rosuvastatin and ramipril ... rosuvastatin and amlodipine ... rosuvastatin and ezetimibe …
Matched Products: … RONAP 20 MG FILM TABLET , FILM TABLET, 28 ADET ... RONAP 20 MG FILM TABLET , FILM TABLET, 84 ADET ... RONAP 40 MG FILM TABLET , FILM TABLET, 28 ADET …

Sultamicillin

Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Description: … Pneumonia and Chronic Obstructive Pulmonary Disease (COPD). ... Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated …
Matched Products: … AMPISID 750 MG FILM TABLET, 10 ADET ... AMPİSİD 375 MG FİLM TABLET, 10 ADET ... DEVASID 375 MG FILM TABLET, 20 ADET …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and gemigliptin ... metformin and ertugliflozin ... metformin and linagliptin ... metformin and sulfonylureas …
Matched Products: … METVEL 850 MG FILM KAPLI TABLET, 50 FILM KAPLI TABLET ... METVEL 850 MG FILM KAPLI TABLET, 100 FILM KAPLI TABLET ... METVEL 1000 MG FILM KAPLI TABLET , 100 FILM KAPLI TABLET …

Voriconazole

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... [L15571] It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … VFEND FILM-COATED TABLET 50 mg ... VFEND FILM-COATED TABLET 200 mg ... VFEND 50 MG FILM TABLET, 14 ADET …

Montelukast

Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … others in individuals who used the medication. ... has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and …
Matched Mixtures name: … LORCLAST 5 MG/10 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET ... DESMONT 5/10 MG 90 FILM KAPLI TABLET ... LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADET …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SINAIR 10 MG FILM KAPLI TABLET ,FILM TABLET, 28 ADET ... OXAIR FILM COATED TABLET 10MG ... AIRMOL 10 MG FILM TABLET, 56 ADET …

Baricitinib

Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Description: … By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune ... European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Olumiant 2mg Film-Coated Tablets ... Olumiant 4mg Film-Coated Tablets ... OLUMIANT FILM-COATED TABLET 2MG …

Finerenone

Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in adults with chronic kidney disease associated with type II diabetes mellitus.[A236519,L34739] Patients with kidney...
Approved
Investigational
Matched Description: … [A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and ... [A236544] Eplerenone is more selective and has longer lasting effects. ... can also have effects at the androgen, progesterone, and glucocorticoid receptors. …
Matched Products: … KERENDIA FILM-COATED TABLET 10MG ... KERENDIA FILM-COATED TABLET 20MG ... KERENDİA 10 MG FİLM KAPLI TABLET, 98 ADET …

Apremilast

Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole.[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted...
Approved
Investigational
Matched Description: … It belongs to the same drug class as [Roflumilast] and [Crisaborole]. ... associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OTEZLA FILM-COATED TABLETS 30 MG ... OTEZLA FILM-COATED TABLETS 20 MG ... OTEZLA FILM-COATED TABLETS 10 MG …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … It is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis ... Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6 ... ) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Yulareb 50mg film-coated tablets ... Yulareb 150mg film-coated tablets ... VERZENIO FILM-COATED TABLET 50MG …

Brigatinib

Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and ... Brigatinib was developed by Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company Limited, and …
Matched Mixtures name: … ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG ... ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG ... ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 23 ADET 180 MG …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ALUNBRIG FILM-COATED TABLET 30mg ... ALUNBRIG FILM-COATED TABLET 90mg ... ALUNBRIG FILM-COATED TABLET 180mg …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … MENTAX 10 MG FILM TABLET,FILM TABLET, 100 ADET ... AXURA 5/10/15/20MG FILM ST ... ALMENTA 15MG FILM TABLET, 28 ADET …
Displaying drugs 651 - 675 of 918 in total