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Displaying drugs 651 - 675 of 3125 in total

Indoleacetic acid

Experimental
Matched Synonyms: … (Indol-3-yl)acetate ... (indol-3-yl)acetic acid ... Indole-3-acetic acid …
Matched Name: … Indoleacetic acid …
Matched Iupac: … 2-(1H-indol-3-yl)acetic acid …
Matched Categories: … Acids, Heterocyclic …

DS-1211

DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Investigational
Matched Synonyms: … N-Acetyl-D-leucine ... N-Acetyl-R-leucine ... D-leucine, N-acetyl- …
Matched Iupac: … (2R)-2-acetamido-4-methylpentanoic acid …
Matched Description: … DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) …

Lauric acid

Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
Approved
Experimental
Matched Synonyms: … C12 fatty acid ... Dodecoic acid ... Dodecanoic acid …
Matched Name: … Lauric acid …
Matched Iupac: … dodecanoic acid …
Matched Description: … Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations ... be treated with various solutes and used to determine their molecular masses. ... Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can …
Matched Categories: … Fatty Acids …

Phenol

Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Acide phénique ... Acide carbolique ... Carbolic acid …
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Premier Value Instant Antiseptic Pain Relief ... Major Camphor and Phenol ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …

4-Nitrophenyl (3S)-3-({N-[(benzyloxy)carbonyl]-L-phenylalanyl}amino)-5-phenyl-1-pentanesulfonate

Experimental
Matched Synonyms: … 3-[N-[Benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonic acid 4-nitro-phenyl ester …

4-Hydroxyphenylglycine

Experimental
Matched Synonyms: … (+/-)-alpha-amino-4-hydroxybenzeneacetic acid ... (RS)-2-(4-hydroxyphenyl)glycine …
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …

Aminopterin

Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Synonyms: … N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid ... 4-aminofolic acid ... 4-aminopteroylglutamic acid …
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …

Methotrexate

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid ... 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid …
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid …
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …

Pyruvic acid

An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-ketopropionic acid ... 2-oxopropanoic acid ... acide pyruvique …
Matched Name: … Pyruvic acid …
Matched Iupac: … 2-oxopropanoic acid …
Matched Description: … An intermediate compound in the metabolism of carbohydrates, proteins, and fats. ... In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous …
Matched Categories: … Keto Acids ... Carboxylic Acids …

Butyric Acid

A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
Experimental
Investigational
Matched Synonyms: … Butanoic acid ... Butyricum acidum ... N-butyric acid …
Matched Name: … Butyric Acid …
Matched Iupac: … butanoic acid …
Matched Description: … A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the …
Matched Categories: … Histamine Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …

(6R)-Folinic acid

Experimental
Matched Synonyms: … L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] ... acid ... (6R,2'S)-Folinic acid …
Matched Name: … (6R)-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Categories: … Folic Acid and Derivatives …

Metenkefalin

Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … Methionine Enkephalin …
Matched Iupac: … 3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido]-4-(methylsulfanyl)butanoic acid …
Matched Description: … Metenkefalin is an endogenous opioid and beta-endorphin. …
Matched Salts name: … Metenkefalin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Methionine …

Leukotriene C4

The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and...
Experimental
Investigational
Matched Synonyms: … )glycine ... (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl ... L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycine …
Matched Iupac: … -carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]sulfanyl}-5-hydroxyicosa-7,9,11,14-tetraenoic acid …
Matched Description: … It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized ... The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular …
Matched Categories: … Fatty Acids ... Arachidonic Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …

Bufexamac

Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, and itching. It...
Approved
Withdrawn
Matched Synonyms: … Bufexamic acid ... 2-(p-Butoxyphenyl)-acetohydroxamic acid ... 4-Butoxyphenylacetohydroxamic acid …
Matched Description: … and itching. ... a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Hydroxy Acids …

N(2)-succinyl-L-arginine

Experimental
Matched Synonyms: … Succinyl-arginine ... N2-Succinyl-L-arginine …
Matched Name: … N(2)-succinyl-L-arginine …
Matched Iupac: … (2S)-5-carbamimidamido-2-[(3-carboxy-1-hydroxypropylidene)amino]pentanoic acid …

Chlorpromazine

The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Description: … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the …
Matched Salts name: … Chlorpromazine hydrochloride …
Matched Categories: … Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … PROZIN ... Chlorpromazine Hydrochloride ... Chlorpromazine hydrochloride …

Arginine aspartate

Experimental
Matched Synonyms: … Arginine L-aspartate ... L-Arginine aspartate ... L-Arginine-L-aspartate …
Matched Name: … Arginine aspartate …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-2-aminobutanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …

Kynurenine

Experimental
Matched Synonyms: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid ... 3-Anthraniloyl-L-alanine …
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …

Betaine

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Acidol ... Glycine betaine ... 2-(Trimethylammonio)Acetate …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and ... levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Glutamic Acid HCl Betaine HCl W Pepsin ... Betaine HCl and Pepsin …
Matched Salts name: … Betaine hydrochloride …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... betaine hydrochloride ... Acid Preparations …

CH-1504 L-isomer

CH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … 4-methylene-n-(4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)-l-glutamic acid ... L-glutamic acid, n-(4-(2-(2,4-diamino-6-quinazolinyl)ethyl)benzoyl)-4-methylene- ... (2s)-2-((4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)amino)-4-methylene-pentanedioic acid …

Zirconium chloride hydroxide

Approved
Experimental
Matched Synonyms: … Zirconium hydroxychloride ... Zirconyl hydroxychloride …

3-nitro-L-tyrosine

Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid ... 3-Nitro-L-tyrosine …
Matched Name: … 3-nitro-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …

Levoleucovorin

Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic ... acid ... L-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … and methionine before incorporation into DNA or protein. ... This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... acid or leucovorin). …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Folic Acid Analogues …

Phosphatidyl serine

Phosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase C (PKC) which has been shown to be involved in memory function. In apoptosis, phosphatidyl serine is transferred to...
Investigational
Nutraceutical
Matched Synonyms: … Phosphatidyl serine …
Matched Name: … Phosphatidyl serine …
Matched Iupac: … (2S)-2-amino-3-({[(2R)-2,3-bis(octadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)propanoic acid …
Matched Description: … Phosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and ... rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase ... PS has been investigated in a small number of double-blind placebo trials and has been shown to increase …
Matched Categories: … Phosphatidic Acids …

Folitixorin

Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- ... 5,10-methylene-(6rs)-tetrahydrofolic acid ... 5,10-methylenetetrahydrofolic acid …
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid …
Matched Categories: … Enzymes and Coenzymes …
Displaying drugs 651 - 675 of 3125 in total