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Displaying drugs 676 - 700 of 5459 in total

Selegiline

A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. ... A selective, irreversible inhibitor of Type B monoamine oxidase. ... (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. …
Matched Salts cas: … 14611-52-0 …
Matched Salts name: … Selegiline hydrochloride …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Compounds used in a research, industrial, or household setting …
Matched Products: … Selegiline Hydrochloride ... SELEGILIN AL 5 ... SELEGILIN AL 10 …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Iupac: … 4-[(2R,3R)-2-(2,2-dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoic acid …
Matched Description: … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially ... [A192987] Chloramphenicol is a bacteriostatic antibiotic. ... Chloramphenicol succinate is an ester prodrug of [chloramphenicol]. …
Matched Salts cas: … 982-57-0 …
Matched Salts name: … Chloramphenicol sodium succinate …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … Chloromycetin Sodium Succinate ... Chloramphenicol Sodium Succinate ... CHLORAMPHENICOL SODIUM SUCCINATE …

Trifluoperazine

A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Matched Description: … It is used as an antipsychotic and an antiemetic. ... A phenothiazine with actions similar to chlorpromazine. …
Matched Salts cas: … 440-17-5 …
Matched Salts name: … Trifluoperazine hydrochloride …
Matched Categories: … Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Trifluoperazine Hydrochloride ... APO-TRIFLUOPERAZINE TABLET 5MG ... TRIFLUOPERAZINE HYDROCHLORIDE …

Metadoxine

Experimental
Matched Synonyms: … Pyridoxine mixture with Pyrrolidonecarboxylic Acid ... Pyridoxine pyroglutamate …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid; 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Vitamins ... Vitamin B Complex …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Description: … An antineoplastic agent used to treat ovarian cancer. …
Matched Salts cas: … 119413-54-6 …
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Drugs that are Mainly Renally Excreted ... MATE 1 Substrates with a Narrow Therapeutic Index ... MATE 2 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … Topotecan hydrochloride ... Topotecan Hydrochloride ... Topotecan Hydrochloride for Injection …

Ertapenem

Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … -7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... -3-carboxylic acid ... (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. …
Matched Salts name: … Ertapenem sodium …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … Ertapenem Sodium ... ERTAPENEM ACS DOBFAR ... ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …

Amantadine

An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Description: … It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic ... in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake. ... An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. …
Matched Mixtures name: … Innoprax-5 ... BREGAMIN AV ... BREGAMIN AV …
Matched Salts name: … Amantadine hydrochloride ... Amantadine sulfate …
Matched Categories: … Influenza A M2 Protein Inhibitor ... Drugs that are Mainly Renally Excreted …
Matched Products: … NEOMİDANTAN 100 MG SERT KAPSÜL, 50 ADET ... AMANTADIN AL 100 ... AMANTADIN AL 200 …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … Magnesium is classified as an alkaline earth metal and has 2 hydration shells. ... and magnesium carbonate. ... as food processing and cooking vegetables (which are normally a rich source of magnesium). …
Matched Mixtures name: … Calcium Folic Acid Plus D Chewable ... One A Day Advance Adults 50+ ... 50 Plus Multiple Vitamins & Minerals …
Matched Products: … MAGNEROT A 500 BEUTEL ... Kordel’s Magnesium Amino Acid Chelate 750 Capsules ... MG 5 LONGORAL …

Gildeuretinol

Investigational
Matched Synonyms: … VITAMIN A ACETATE C20-D3 …

Larsucosterol

Investigational
Matched Synonyms: … 5-cholesten-3.beta.-25-diol-3-sulfate ... 5-cholesten-3.beta., 25-diol 3-sulfate ... 25-hydroxycholest-5-en-3.beta.-yl hydrogen sulfate …
Matched Iupac: … phenanthren-7-yl]oxidanesulfonic acid ... -methylheptan-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Salts cas: … 1174047-40-5 …
Matched Salts name: … Larsucosterol sodium …

Hydroxyzine

Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched International brands: … Vistaject-50 …
Matched Description: … and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. ... [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … AA PHARMA HYDROXYZINE CAPSULE 10 mg ... AA PHARMA HYDROXYZINE CAPSULE 25 mg ... Hydroxyzine hydrochloride …

MIV-711

Investigational
Matched Synonyms: … fluoro-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide hydrochloride ... )-1-[(3aS,6R,6aR)-6-Ethynyl-3-oxohexahydro-2H-furo[3,2-b]pyrrol-4-yl]-4-methyl-1-oxopentan-2-yl]-4-[5- …

Oxymorphone

An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,5R,13R,17S)-10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough ... 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and ... It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092 …
Matched Salts name: … Oxymorphone hydrochloride …
Matched Products: … Numorphan Suppository 5mg ... Oxymorphone Hydrochloride ... Oxymorphone hydrochloride …

Aminohippuric acid

The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … Aminohippuric acid ... 4-aminohippuric acid ... p-aminohippuric acid …
Matched Name: … Aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory ... The glycine amide of 4-aminobenzoic acid. …
Matched Salts name: … Aminohippurate sodium …
Matched Categories: … Indicators and Reagents ... Benzamides and benzamide derivatives ... Tests for Renal Function and Ureteral Injuries ... Keto Acids ... Acids, Carbocyclic …
Matched Products: … Aminohippurate Sodium Pah ... Aminohippurate Sodium Inj Liq 20% …

Nitrous acid

Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Matched Synonyms: … dioxonitric acid …
Matched Name: … Nitrous acid …
Matched Iupac: … nitrous acid …
Matched Description: … Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to ... applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and ... needed in a basic health system. …
Matched Mixtures name: … Rite Aid Enamel Guard …
Matched Salts name: … Sodium nitrite …
Matched Categories: … Diet, Food, and Nutrition ... Indicators and Reagents ... sodium nitrite ... Sodium Compounds ... Acids …
Matched Products: … Sodium Nitrite ... Sodium Nitrite Injection, USP …

Methohexital

An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid ... (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia …
Matched Salts name: … Methohexital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Brietal 500 mg - Trockenstechampulle ... Brevital Sodium ... Brietal Sodium Ampoule 660 …

gamma-Tocopherol

gamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).
Investigational
Matched Synonyms: … D-gamma-Tocopherol …
Matched Name: … gamma-Tocopherol …
Matched Description: … to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics). ... gamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness …
Matched Categories: … Diet, Food, and Nutrition ... Tocopherols ... Vitamins ... Vitamin E ... Vitamins (Fat Soluble) …

Sulfur hexafluoride

Sulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric...
Approved
Matched Synonyms: … Sulfur fluoride ... sulfur(6+) fluoride ... sulfur(VI) fluoride …
Matched Iupac: … hexafluoro-λ⁶-sulfane …
Matched Description: … the left ventricular chamber and to improve the delineation of the left ventricular endocardial border ... echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and ... Sulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify …
Matched Categories: … Fluorides ... Fluorine Compounds …

Ascorbyl glucoside

Experimental
Matched Synonyms: … Ascorbic acid 2-O-glucoside ... AA-2G …
Matched Name: … Ascorbyl glucoside …
Matched Iupac: … (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan …
Matched Categories: … Sugar Acids ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Products: … Sandawha Vitamin C Brightening Essence …

Aracytidine 5'-monophosphate

Experimental
Matched Synonyms: … Ara-5'-CMP ... Aracytidine 5'-phosphate ... Cytosine arabinose-5'-phosphate …
Matched Name: … Aracytidine 5'-monophosphate …
Matched Iupac: … acid ... {[(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …

Hexadecanesulfonyl fluoride

Experimental
Matched Synonyms: … 1-Hexadecanesulfonyl fluoride ... Hexadecane-1-sulfonyl fluoride …
Matched Name: … Hexadecanesulfonyl fluoride …
Matched Iupac: … hexadecane-1-sulfonyl fluoride …
Matched Categories: … Fatty Acids ... Palmitic Acids …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched International brands: … Apo-Metformin …
Matched Description: … It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Sitagliptin Phosphate/Metformin Hydrochloride ... JANUMET 50/850MG (SITAGLIPTIN PHOSPHATE/METFORMIN HCI) ... JANUMET 50/500MG (SITAGLIPTIN PHOSPHATE/METFORMIN HCI) …
Matched Salts name: … Metformin hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and acarbose ... metformin and gemigliptin ... metformin and linagliptin ... metformin and evogliptin …
Matched Products: … METFORMIN AL 500 ... Glycomet - 500 SR (Metformin Hydrochloride Sustained Release Tablets 500 mg) ... Proglutrol 500 (Metformin Hydrochloride Extended-Release Tablets 500mg) …

ABBV-CLS-7262

Investigational
Matched Synonyms: … Sodium ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen ... phosphate - 2-amino-2- (hydroxymethyl)propane-1,3-diol (1/1/1) …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido ... ]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate …

Dicloxacillin

One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Synonyms: … thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4- …
Matched Iupac: … [3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Salts cas: … 343-55-5 …
Matched Salts name: … Dicloxacillin sodium ... Dicloxacillin sodium anhydrous …
Matched Products: … Dicloxacillin Sodium ... DICLOXACILINA 250 MG POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... ไดคล็อกเมด 500 …

Clonidine

Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.[L7237,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.
Approved
Matched Description: … [A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. ... Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. …
Matched Salts name: … Clonidine hydrochloride …
Matched Categories: … clonidine and diuretics ... Antiglaucoma Preparations and Miotics ... clonidine and diuretics, combinations with other drugs ... Adrenergic alpha-Agonists ... Central Alpha-agonists …
Matched Products: … Apo-clonidine ... Apo-clonidine Tab 0.1mg ... Apo-clonidine Tab 0.2mg …
Displaying drugs 676 - 700 of 5459 in total