Displaying drugs 7001 - 7025 of 8282 in total
IR501
IR501 (Ravax) is a potential first-in-class vaccine for the treatment of Rheumatoid Arthritis. It specifically targets autoreactive T-cells, reducing their activity. It was last known to be in phase III clinical trials.
Investigational
Matched Description: … IR501 (Ravax) is a potential first-in-class vaccine for the treatment of Rheumatoid Arthritis. …
AAV-AIPL
AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human AIPL1 gene. Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in AIPL1 gene.
Investigational
Matched Description: … Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due …
Vepdegestrant
Vepdegestrant is under investigation in clinical trial NCT05909397 (A Study of ARV-471 (PF-07850327) Plus Palbociclib Versus Letrozole Plus Palbociclib in Participants With Estrogen Receptor Positive, Human Epidermal Growth Factor Negative Advanced Breast Cancer).
Investigational
Matched Description: … Vepdegestrant is under investigation in clinical trial NCT05909397 (A Study of ARV-471 (PF-07850327) …
Cofirasersen
Cofirasersen is under investigation in clinical trial NCT04441788 (A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)).
Investigational
Matched Description: … investigation in clinical trial NCT04441788 (A Study to Assess the Safety, Tolerability, and Efficacy of …
5-androstenedione
5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its use in athletes is prohibited by The World Anti-Doping Agency. Apart from the positioning of a carbon-carbon double bond, its...
Experimental
Illicit
Matched Description: … 5-androstenedione is a prohormone of testosterone. ... Apart from the positioning of a carbon-carbon double bond, its structure is similar to [4-androstenedione …
Ularitide
Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Description: … involved in regulating blood pressure and the excretion of water and sodium from the kidneys. ... Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is …
Synephrine
Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine.
The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source...
Experimental
Matched Description: … The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source of …
Davunetide
Davunetide has been used in trials studying the treatment of Progressive Nonfluent Aphasia, Progressive Supranuclear Palsy, Predicted Tauopathies, Including, Corticobasal Degeneration Syndrome, and Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17.
Davunetide is the first drug to improve memory performance by impacting the mechanisms that lead to physical damage in...
Investigational
Matched Description: … Davunetide has been used in trials studying the treatment of Progressive Nonfluent Aphasia, Progressive ... impacting the mechanisms that lead to physical damage in the brain caused by neurofibrillary tangles, one of …
Stem-cell derived exosome vesicle products
Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including paracrine factors such as exosomes. Exosomes are nanometer-sized, membrane-bound vesicles secreted for the purpose of cell-cell communication. Once secreted into extracellular fluid, exosomes are taken up by their target cells or carried to distant target sites. Various bioactive...
Investigational
Matched Description: … Exosomes are nanometer-sized, membrane-bound vesicles secreted for the purpose of cell-cell communication ... While many contain a conserved set of proteins, they also carry unique tissue type-specific proteins. ... These exosomes can also consist of VEGF and matrix metalloproteinase-9 (MMP-9) which aid in angiogenesis …
Patupilone
Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.
Experimental
Investigational
Matched Description: … Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol. …
Seratrodast
Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Experimental
Matched Description: … Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. …
Letosteine
Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
Experimental
Matched Description: … Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions …
Afuresertib
Afuresertib has been used in trials studying the treatment of Cancer and Neoplasms, Haematologic.
Investigational
Matched Description: … Afuresertib has been used in trials studying the treatment of Cancer and Neoplasms, Haematologic. …
PF-03758309
PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.
Investigational
Matched Description: … PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors. …
Crocin
Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia.
Investigational
Matched Description: … Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia …
Elamipretide
Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
Investigational
Matched Description: … Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy. …
MK-0812
MK0812 has been used in trials studying the treatment of Relapsing-Remitting Multiple Sclerosis.
Investigational
Matched Description: … MK0812 has been used in trials studying the treatment of Relapsing-Remitting Multiple Sclerosis. …
Sorivudine
Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
Investigational
Matched Description: … Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections. …
CERC-301
Mk 0657 has been used in trials studying the treatment of Major Depressive Disorder.
Investigational
Matched Description: … Mk 0657 has been used in trials studying the treatment of Major Depressive Disorder. …
Vidupiprant
Vidupiprant has been used in trials studying the treatment and basic science of Asthma.
Investigational
Matched Description: … Vidupiprant has been used in trials studying the treatment and basic science of Asthma. …
Ricolinostat
Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
Investigational
Matched Description: … Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer …
Imeglimin
Imeglimin has been used in trials studying the treatment of Type 2 Diabetes Mellitus.
Investigational
Matched Description: … Imeglimin has been used in trials studying the treatment of Type 2 Diabetes Mellitus. …
Batefenterol
Batefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Description: … Batefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive …
MK-5108
MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors.
Investigational
Matched Description: … MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors. …
Netivudine
Netivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
Investigational
Matched Description: … Netivudine has been used in trials studying the treatment of Chickenpox and HIV Infections. …
Displaying drugs 7001 - 7025 of 8282 in total