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VLX-1570

VLX-1570 is under investigation in clinical trial NCT02372240 (A Study of VLX1570 and Dexamethasone in Myeloma Patients).
Investigational
Matched Synonyms: … (3E,5E)-3,5-Bis[(4-Fluoro-3-Nitrophenyl)Methylidene]-1-(Prop-2-Enoyl)Azepan-4-0Ne …
Matched Iupac: … (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-one …
Matched Description: … VLX-1570 is under investigation in clinical trial NCT02372240 (A Study of VLX1570 and Dexamethasone in …

Taminadenant

Investigational
Matched Synonyms: … 4-pyrimidinamine, 5-bromo-2,6-di-1h-pyrazol-1-yl- …

Mevalonic acid

Experimental
Matched Synonyms: … (R)-3,5-dihydroxy-3-methylvaleric acid ... 3,5-Dihydroxy-3-methylvaleric acid …
Matched Iupac: … (3R)-3,5-dihydroxy-3-methylpentanoic acid …

Gold sodium thiosulfate

Experimental
Matched Synonyms: … Sodium aurothiosulfate ... Gold sodium thiosulfate anhydrous ... Sodium aurothiosulfate anhydrous …
Matched Name: … Gold sodium thiosulfate …
Matched Iupac: … trisodium 1,5-dioxa-2lambda6,3,6lambda6,7-tetrathia-4-auraspiro[3.3]heptane-2,2,6,6-tetrone …
Matched Categories: … Sodium Compounds …

2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione

Experimental
Matched Name: … 2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione …
Matched Iupac: … 2-{4-[4-hydroxy-3-(propan-2-yl)phenoxy]-3,5-dimethylphenyl}-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione …

CHF-6333

Investigational
Matched Synonyms: … (r)-2-(5-cyano-2-(6-(methoxycarbonyl)-7-methyl-3-oxo-8-(3-(trifluoromethyl)phenyl)-2,3,5,8-tetrahydro ... (r)-2-(5-cyano-2-(6-(methoxycarbonyl)-7-methyl-3-oxo-8-(3-(trifluoromethyl)phenyl)-2,3,5,8-tetrahydro ... 3-oxo-8-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,3-a)pyrimidin-5-yl)-, methanesulfonate (1:1) …
Matched Iupac: … ]triazolo[4,3-a]pyrimidin-5-yl]phenyl}ethyl)trimethylazanium methanesulfonate ... (2-{5-cyano-2-[(5R)-6-(methoxycarbonyl)-7-methyl-3-oxo-8-[3-(trifluoromethyl)phenyl]-2H,3H,5H,8H-[1,2,4 …

Bivalirudin

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Iupac: … }-2-(4-hydroxyphenyl)ethyl]carbamoyl}propyl]carbamoyl}propyl]carbamoyl}pyrrolidin-1-yl]-3-methyl-1-oxopentan ... carbamoylpropanamido]acetamido}-3-carboxypropanamido]-3-phenylpropanamido]-4-carboxybutanamido]-4-{[( ... (4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-(2-{2-[2-(2-{[(2S)-1-[(2S)-2-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl ... 2S,3S)-1-[(2S)-2-{[(1S)-3-carboxy-1-{[(1S)-3-carboxy-1-{[(1S)-1-{[(1S)-1-carboxy-3-methylbutyl]carbamoyl ... formamido}-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}acetamido)acetamido]acetamido}acetamido)-3- …
Matched Description: … monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Bivalirudin in 0.9% Sodium Chloride …

Potassium gluconate

Potassium gluconate is a salt of DB01345 and is classified as a food additive by the FDA . It is also used as a potassium supplement . Potassium is an essential nutrient. It is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining...
Approved
Matched Iupac: … potassium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate …
Matched Description: … Potassium gluconate is believed to be more palatable and non-acidifying than potassium chloride (KCl) ... In dietary supplements, potassium is often present as potassium chloride, but many other forms—including ... Potassium gluconate is a salt of [DB01345] and is classified as a food additive by the FDA [L2654]. …
Matched Mixtures name: … Spectra 301 Vitamin and Mineral Supp ... Cal-mag Plus K, Mn and Zn Caplets ... Multivitamins and Minerals for Young Men …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … ION-K SOLUCIÓN ORAL 31.2% …

3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL

Experimental
Matched Name: … 3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL …
Matched Iupac: … 3-({4-amino-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl}methyl)phenol …

Erdafitinib

In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Iupac: … N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-{2-[(propan-2-yl)amino]ethyl}quinoxalin-6-amine …
Matched Description: … for patients with metastatic bladder cancer, which demonstrates the development of more personalized and ... [L5956, L5959] At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP3A4 Inducers …
Matched Products: … BALVERSA FILM-COATED TABLETS 3MG ... BALVERSA FILM-COATED TABLETS 4MG ... BALVERSA 3 MG FİLM KAPLI TABLET, 56 ADET …

Gunagratinib

Investigational
Matched Synonyms: … (s)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1h-pyrazole-4-carboxamide ... 1h-pyrazole-4-carboxamide, 3-(2-(3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1-((3s)-1-(1-oxo-2-propen ... -1-yl)-3-pyrrolidinyl)- …
Matched Iupac: … 3-[2-(3,5-dimethoxyphenyl)ethynyl]-5-(methylamino)-1-[(3S)-1-(prop-2-enoyl)pyrrolidin-3-yl]-1H-pyrazole ... -4-carboxamide …

Chlorphenesin

Approved
Experimental
Matched Synonyms: … 3-(p-chlorophenoxy)propane-1,2-diol ... 3-(4-chlorophenoxy)-1,2-propanediol ... 3-(p-chlorophenoxy)-1,2-propanediol …
Matched Iupac: … 3-(4-chlorophenoxy)propane-1,2-diol …
Matched Categories: … Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP3A4 Inducers (strength unknown) …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Synonyms: … N-Acetyl-4-aminobenzenesulfonamide ... N(1)-Acetyl-4-aminophenylsulfonamide ... p-Aminobenzenesulfonacetamide …
Matched Iupac: … N-(4-aminobenzenesulfonyl)acetamide …
Matched Description: … An anti-infective agent that is used topically to treat skin infections and orally for urinary tract …
Matched Mixtures name: … Sodium Sulfacetamide 8% and Sulfur 4% ... Sodium Sulfacetamide 8% and Sulfur 4% ... Sodium Sulfacetamide 9.8% and Sulfur 4.8% …
Matched Salts name: … Sulfacetamide sodium …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … PMS-sulfacetamide Sod Oph Soln 30% ... PMS-sulfacetamide Sodium Liq 10% ... Sodium Sulamyd Oph Dps 30% …

Sodium sulfate

Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Sodium sulfate...
Approved
Vet approved
Matched Synonyms: … Anhydrous sodium sulfate ... Sodium sulfate anhydrous ... Sodium sulfate, anhydrous …
Matched Name: … Sodium sulfate …
Matched Description: … Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. ... does not disturb normal electrolyte balance and does not lead to absorption or excretion of water and ... Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of …
Matched Salts cas: … 7727-73-3 …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350 and Electrolytes ... PEG-3350 and Electrolytes …
Matched Salts name: … Sodium sulfate decahydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Ions ... Sodium ... sodium sulfate ... sodium sulfate …

Penciclovir

Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Synonyms: … 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine ... 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine ... 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. …
Matched Salts name: … Penciclovir sodium …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …

Chlorpropamide

Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzenesulfonyl)-3-propylurea ... 1-(p-chlorophenylsulfonyl)-3-propylurea ... 1-propyl-3-(p-chlorobenzenesulfonyl)urea …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …
Matched Description: … of retinopathy (UKPDS-33). ... increase the number and sensitivity of insulin receptors. ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2C19 Substrates ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones …
Matched Products: … ORBİN 250 MG TABLET, 40 ADET …

Esatenolol

Esatenolol is a beta blocker.
Experimental
Matched Synonyms: … 2-(p-((2S)-2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide ... S-(-)-4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetamide ... (S)-4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide …
Matched Iupac: … 2-{4-[(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy]phenyl}acetamide …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Substrates …

Propantheline

A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Approved
Matched International brands: … Pro Banthine …
Matched Description: … A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment …
Matched Salts cas: … 50-34-0 …
Matched Salts name: … Propantheline bromide …
Matched Categories: … Alimentary Tract and Metabolism ... propantheline and psycholeptics ... Heterocyclic Compounds, 3-Ring …
Matched Products: … Propantheline Bromide ... Pro-Banthine ... Pro-banthine Tablets 15mg …

Suprofen

An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … (±)-2-(p-(2-thenoyl)phenyl)propionic acid ... 2-(4-(2-Thenoyl)phenyl)propionsäure ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Propionates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Inhibitors …

(S)-4-hydroxymandelonitrile

Experimental
Matched Synonyms: … (2S)-Hydroxy(4-hydroxyphenyl)ethanenitrile ... 4-Hydroxy-L-mandelonitrile …
Matched Name: … (S)-4-hydroxymandelonitrile …
Matched Iupac: … (2S)-2-hydroxy-2-(4-hydroxyphenyl)acetonitrile …

4-(Isopropylamino)diphenylamine

4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen. Sensitivity to this compound may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 4-Anilino-N-isopropylaniline ... N-Isopropyl-N'-phenyl-p-phenylenediamine ... p-Phenylenediamine, N-isopropyl-N'-phenyl …
Matched Name: … 4-(Isopropylamino)diphenylamine …
Matched Iupac: … N1-phenyl-N4-(propan-2-yl)benzene-1,4-diamine …
Matched Description: … 4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant …

Glyburide

Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Synonyms: … 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea ... 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide ... 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea …
Matched Iupac: … 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide …
Matched Description: … through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and ... calcium ion concentrations. ... [L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120] …
Matched Mixtures name: … GLIBOMET FİLM KAPLI TABLET, 40 ADET ... DUPLAX 500 MG/5 MG FILM KAPLI TABLET, 30 ADET ... DUPLAX 500 MG/2.5 MG FILM KAPLI TABLET, 30 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Inhibitors ... Cytochrome P-450 CYP2C19 Substrates ... Cytochrome P-450 CYP3A Inhibitors …
Matched Products: … DIYABEN 3,5 MG TABLET, 30 ADET ... DIYABEN 3,5 MG TABLET, 120 ADET ... PMS-glyburide …

NPT520-34

Investigational
Matched Synonyms: … 4-(4-((4-chloro-3-(trifluoromethyl)phenyl)sulfonyl)phenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione …
Matched Name: … NPT520-34 …

Dalosirvat

Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia).
Investigational
Matched Synonyms: … 1-(2,3-dihydro-benzo(1,4)dioxin-6-yl)-4-phenyl-butane-1,4-dione ... 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-butane-1,4-dione ... 1,4-butanedione, 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl- …
Matched Description: … Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and …

4-Vinylguaiacol

Experimental
Matched Synonyms: … 4-hydroxy-3-methoxystyrene ... p-vinylguaiacol ... 2-(4-hydroxy-3-methoxyphenyl)ethene …
Matched Name: … 4-Vinylguaiacol …
Matched Iupac: … 4-ethenyl-2-methoxyphenol …
Matched Categories: … Phenols ... Phenyl Ethers …
Displaying drugs 701 - 725 of 5758 in total