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Displaying drugs 701 - 725 of 2920 in total
Approved
Vet approved
Matched Synonyms: … Cortisol 21-phosphate ... Hydrocortisone 21-phosphate
Matched Name: … Hydrocortisone phosphate
Matched Iupac: … 3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic acid
Matched Salts name: … Hydrocortisone sodium phosphate
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Synonyms: … (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. ... The sodium salt has been also used to treat primary pulmonary hypertension. …
Matched Salts name: … Epoprostenol sodium
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Products: … Epoprostenol Sodium
Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Synonyms: … Acide tiludronique ... Tiludronic acid ... Acido tiludronico …
Matched Name: … Tiludronic acid
Matched Iupac: … {[(4-chlorophenyl)sulfanyl](phosphono)methyl}phosphonic acid
Matched Description: … ] and [clodronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and ... [A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763] …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... tiludronic acid
Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
Experimental
Matched Synonyms: … Niflumic acid ... Acido niflumico ... Acide niflumique …
Matched Name: … Niflumic acid
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid
Matched Description: … Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis …
Matched Categories: … Niflumic Acid and Prodrugs ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic …
Iotroxic acid is a contrast medium molecule.
Experimental
Withdrawn
Matched Synonyms: … Iotroxic acid ... Acido iotroxico ... Acide iotroxique …
Matched Name: … Iotroxic acid
Matched Iupac: … (2-{[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]methoxy}ethoxy)ethoxy]acetamido}-2,4,6-triiodobenzoic acid
Matched Description: … Iotroxic acid is a contrast medium molecule. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iotroxic acid ... Triiodobenzoic Acids
Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Synonyms: … Acide pamidronique ... Pamidronic acid ... Acido pamidronico …
Matched Name: … Pamidronic acid
Matched Iupac: … (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
Matched Description: … ] and [alendronic acid]. ... ], [zoledronic acid], [minodronic acid], and [risedronic acid] are becoming more popular. ... Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... pamidronic acid
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Experimental
Matched Synonyms: … Nicotinamide adenine dinucleotide ... Nicotinamide-adenine dinucleotide ... beta-Nicotinamide adenine dinucleotide …
Matched Description: … A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate ... electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Adenine Nucleotides ... Enzymes and Coenzymes …
Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Approved
Investigational
Matched Synonyms: … Zinc chloride
Matched Name: … Zinc chloride
Matched Description: … levels and prevent deficiency syndromes. ... [L14189] Zinc chloride was granted FDA approval before 26 June 1986.[L14189] ... Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc …
Matched Mixtures name: … Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride
Matched Categories: … Acids ... Acids, Noncarboxylic ... zinc chloride ... Chlorine Compounds ... Basic Ointments and Protectants …
Matched Products: … Zinc Chloride ... Perioselect Zinc Chloride Solution 1% …
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows …
Matched Salts name: … Sildenafil citrate
Matched Products: … Sildenafil Citrate ... SILDENAFIL CITRATE ... sildenafil CITRATE
Experimental
Matched Synonyms: … Pyridoxamine phosphate
Matched Name: … Pyridoxamine-5'-Phosphate
Matched Iupac: … {[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid
Experimental
Matched Synonyms: … Acido sulfurico ... Acide sulfurique ... Brimstone acid
Matched Name: … Sulfuric acid
Matched Iupac: … sulfuric acid
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … 2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid ... pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Salts name: … Ertapenem sodium
Matched Products: … Ertapenem Sodium
Investigational
Matched Synonyms: … (((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)-d-tryptophyl-, sodium
Matched Iupac: … sodium (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
Matched Categories: … Amino Acids, Peptides, and Proteins …
5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Experimental
Matched Synonyms: … Uridine phosphate ... 5'-uridylic acid ... Uridine 5'-phosphoric acid
Matched Iupac: … 3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Matched Description: … 5'-Uridylic acid. ... A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups. It has been widely used for over 50 years, most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. Its...
Approved
Matched Description: … Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and ... a means of neuromuscular blockade during intubation and surgical procedures. ... [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as …
Matched Salts name: … Succinylcholine chloride dihydrate ... Succinylcholine chloride
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Matched Products: … Succinylcholine Chloride ... SUXAMETHONIUM CHLORIDE INJECTION B.P ... Succinylcholine Chloride Injection USP …
Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Approved
Matched Synonyms: … Calcium glubionate anhydrous
Matched Name: … Calcium glubionate anhydrous
Matched Categories: … Alimentary Tract and Metabolism …
Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched Description: … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function ... to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system …
Matched Salts name: … Bethanechol chloride
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Matched Products: … Bethanechol chloride ... Bethanechol Chloride ... PHL-bethanechol Chloride
Investigational
Matched Synonyms: … cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Copper(1+) chloride
Matched Name: … Cuprous chloride
Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Synonyms: … Gadobenic acid ... Acide gadobenique ... Acido gadobenico …
Matched Name: … Gadobenic acid
Matched Description: … other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and ... [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based …
Matched Categories: … gadobenic acid
Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds, including pharmaceuticals such as DB00472 (Prozac). It is used as a chemical reagent in several industrial processes such as oil refinery. It is also used as etchant, cleaning agent, and a reagent to...
Approved
Investigational
Matched Synonyms: … Hydrofluoric acid ... Hydrogen fluoride, anhydrous
Matched Description: … It is also used as etchant, cleaning agent, and a reagent to dissolve oxides and silicates. ... Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens ... Denti-Care Topical Sodium Fluoride Strawberry ... Acidulated Phosphate Fluoride Oral Solution …
Matched Categories: … Acids ... Acids, Noncarboxylic …
Colestilan is an ingredient in the EMA-withdrawn product BindRen.
Approved
Investigational
Withdrawn
Matched Synonyms: … Colestilan chloride
Matched Name: … Colestilan chloride
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Approved
Vet approved
Matched Description: … Pralidoxime is an antidote to organophosphate pesticides and chemicals. ... bond formed between the organophosphate and acetylcholinesterase. ... hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester …
Matched Mixtures name: … ATNAA atropine and pralidoxime chloride Auto-Injector …
Matched Salts name: … Pralidoxime chloride
Matched Categories: … pralidoxime and atropine …
Matched Products: … Protopam Chloride ... Pralidoxime Chloride ... Protopam Chloride Inj 1gm …
Experimental
Matched Synonyms: … Pyridoxine 5-phosphate
Matched Name: … Pyridoxine phosphate
Matched Iupac: … {[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methoxy}phosphonic acid
Matched Categories: … Enzymes and Coenzymes …
Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse.
Investigational
Matched Synonyms: … Glycerone phosphate ... 3-hydroxy-2-oxopropyl phosphate ... 1,3-Dihydroxyacetone 1-phosphate
Matched Name: … Dihydroxyacetone phosphate
Matched Iupac: … (3-hydroxy-2-oxopropoxy)phosphonic acid
Matched Description: … Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. ... Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse. …
Matched Categories: … Sugar Phosphates
Displaying drugs 701 - 725 of 2920 in total