Displaying drugs 701 - 725 of 12071 in total
Nitrofurantoin
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Description: … Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. ... [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole]. …
Heparin
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … It is a naturally occurring anticoagulant released from mast cells. ... Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers ... infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a …
Meclofenamic acid
A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Approved
Vet approved
Matched Description: … A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. …
Dichlorobenzyl alcohol
Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated with mouth and throat infections. Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical. On the other...
Approved
Matched Description: … Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated …
Amaranthus palmeri pollen
Amaranthus palmeri pollen is the pollen of the Amaranthus palmeri plant. Amaranthus palmeri pollen is mainly used in allergenic testing.
Approved
Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Description: … booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus ... strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a ... vaccine contains Haemophilus b capsular polysaccharide (polyribosyl-ribitol-phosphate [PRP]), which is a …
Tavaborole
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Description: … Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, ... a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes …
Varenicline
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … Varenicline is a prescription medication used to treat smoking addiction. ... A full agonism was displayed on alpha7-receptors.
On March 9, 2015, the U.S. ... Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine …
Soybean oil
Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. The...
Approved
Matched Description: … Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated ... It is used as a cooking oil and lipid emulsion for parenteral nutrition in clinical settings. ... It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g …
Lithium citrate
Approved
Pivmecillinam
Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Matched Description: … Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed …
Thyrotropin alfa
Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Description: … Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests ... It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients ... It is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit …
Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Description: … a light chain linked by a disulfide bond. ... It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective …
Cinnamyl alcohol
Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as DB14184 within commercial products.
Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% . Sensitivity...
Approved
Experimental
Matched Description: … Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266 ... Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. ... Sensitivity to cinnamyl alcohol may be identified with a clinical patch test. …
Tiaprofenic acid
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Description: … Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly …
Bioallethrin
Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1:1, where both isomers are active ingredients. A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin. A mixture containing only S-forms...
Approved
Experimental
Matched Description: … Bioallethrin is a synthetic pyrethroid used as a pesticide against household pest insects such as mosquitoes ... Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an ... A mixture containing only S-forms of allethrin is referred to as esbioallethrin or S-bioallethrin. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Lonicera caprifolium flower
Lonicera caprifolium flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Lonicera caprifolium flower is a plant/plant extract used in some OTC (over-the-counter) products. …
Juniper tar
Approved
Experimental
Disopyramide
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Approved
Matched Description: … membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar ... A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac …
Levocabastine
Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.
Approved
Investigational
Matched Description: … Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis …
Flavoxate
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Description: … A drug that has been used in various urinary syndromes and as an antispasmodic. ... local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a …
Solidago canadensis pollen
Solidago canadensis pollen is the pollen of the Solidago canadensis plant. Solidago canadensis pollen is mainly used in allergenic testing.
Approved
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Description: … a deficiency in GAA. ... Compared to alglucosidase alfa, cipaglucosidase alfa has a higher M6P content. ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Description: … Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... antigens of *Streptococcus pneumoniae* serotype 10A individually conjugated to the CRM197 protein, a …
Displaying drugs 701 - 725 of 12071 in total