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Displaying drugs 701 - 725 of 6893 in total
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of norepinephrine. It has been used primarily as a vasoconstrictor in the treatment of hypotension.
Approved
Investigational
An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Approved
Investigational
Tragacanth allergenic extract is used in allergenic testing.
Approved
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Approved
Withdrawn
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Mixtures name: … RAMIPRIL COMP HEU 5/25MG N ... VALSARTAN HCT MK 80 MG/12.5 MG COMPRIMIDOS RECUBIERTOS …
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Synonyms: … Glucosamine ... D-Glucosamine
Matched Name: … Glucosamine
Matched Description: … [A232289] Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits ... Glucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance …
Matched Mixtures name: … UHC Glucosamine Chondroitin MSM Capsule ... Bio-Life Glucosamine 500mg tablet ... GLUCOSAMINE & CHONDROITIN 500/400 MG …
Matched Salts name: … Glucosamine sulfate ... Glucosamine hydrochloride ... Glucosamine sulfate sodium chloride ... Glucosamine sulfate potassium chloride …
Matched Categories: … glucosamine
Matched Products: … GLUCOSAMINE POWDER ... GNC Glucosamine 1000 ... HS Glucosamine 500mg Capsule …
N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties. It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties. Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities...
Approved
Matched Synonyms: … N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) cation …
Matched Name: … N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) …
Matched Description: … N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties ... absorption and exposure, although the formal mechanism of action of quaternary ammonium compounds like n-alkyl …
Matched Salts name: … N-alkyl ethylbenzyl dimethyl ammonium chloride (C12-C14) …
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Synonyms: … N-acetyl homotaurine ... N-Acetylhomotaurine …
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematologic disease characterized by hemolysis, thrombophilia, and bone marrow dysfunction.[A263501,L50417] Both hemolysis and thrombophilia are mediated primarily by the complement system. Standard therapy for PNH involves the use of complement C5 inhibitors (e.g. eculizumab, ravulizumab) which are effective in mitigating complement-mediated intravascular...
Approved
Investigational
Matched Synonyms: … (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidine-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridine-2-yl)-4 ... (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine …
Matched Iupac: … (2S,4R)-1-{2-[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine …
Polihexanide has been used in trials studying the treatment, prevention, and supportive care of Caries, Neoplasm, Skin Diseases, Nail Diseases, and Dental Plaque, among others.
Approved
Investigational
Matched Synonyms: … Poly(hexamethylene biguanide) …
Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication...
Approved
Vet approved
Matched Synonyms: … N-(p-methoxybenzyl)-N',N'-dimethyl-N-(α-pyridyl)ethylenediamine ... N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine ... N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine …
Matched Iupac: … N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine …
Matched Mixtures name: … Poly Hist Pd ... Poly Hist Forte ... Poly Hist Dhc …
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Synonyms: … N,N,α-trimethyl-10H-phenothiazine-10-ethanamine ... N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine ... (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine …
Matched Description: … ., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946. …
Matched Products: … ATOSIL N ... CLOSIN N 25MG …
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … 3-hydroxy-N,N-dimethyl-N-ethylanilinium ... N-ethyl-3-hydroxy-N,N-dimethylanilinium ... N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium …
Matched Iupac: … N-ethyl-3-hydroxy-N,N-dimethylanilinium …
A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Approved
Nutraceutical
Matched Synonyms: … N,N,N-trimethylethanol-ammonium ... N-trimethylethanolamine …
Approved
Experimental
Matched Synonyms: … N,N'-Bis(hydroxymethyl) urea ... N-(1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-N,N'-bis(hydroxymethyl)urea …
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Synonyms: … N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide ... N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
Diethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, DEET formulations are used to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and/or tick-borne illnesses like Lyme...
Approved
Matched Synonyms: … 3-methyl-N,N-diethylbenzamide ... N,N-diethyl-m-toluamide …
Matched Iupac: … N,N-diethyl-3-methylbenzamide …
Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Approved
Investigational
Matched Synonyms: … N,N-Bis(3-phenylpropyl)ethylamine ... N-Ethyl-N-(3-phenylpropyl)benzenepropanamine ... N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine …
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Approved
Vet approved
Matched Synonyms: … N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine ... Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether …
Matched Mixtures name: … N - Time ... N - Time Sinus ... Poly Hist Forte …
Matched Products: … HOGGAR N
Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Synonyms: … N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamide …
Matched Iupac: … N1,N3-bis(2,3-dihydroxypropyl)-5-[2-hydroxy-N-(2-hydroxyethyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide …
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Synonyms: … (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide ... N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamide …
Matched Iupac: … (2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide …
Sulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.
Approved
Matched Synonyms: … N-Benzoylsulfanilamide ... N-Sulfanilylbenzamide …
Matched Iupac: … N-(4-aminobenzenesulfonyl)benzamide …
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine ... 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine ... N-(3-dimethylaminopropyl)-3-chlorophenothiazine …
Displaying drugs 701 - 725 of 6893 in total