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Displaying drugs 51 - 75 of 8772 in total
Practolol
A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Approved
Matched Synonyms: … 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol ... 4'-(2-hydroxy-3-(isopropylamino)propoxy)acetanilide ... N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide …
Matched Iupac: … N-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
Matched Iupac: … N-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
Panobinostat
Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Matched Synonyms: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide ... 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)- …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …
Gadopiclenol
Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Synonyms: … (.alpha.3,.alpha.6,.alpha.9-tris(3-((2,3-dihydroxypropyl)amino)-3-oxopropyl)-3,6,9,15-tetraazabicyclo ... (9.3.1)pentadeca-1(15),11,13-triene-3,6,9-triacetato(3-)-.kappa.n3,.kappa.n6,.kappa.n9,.kappa.n15,.kappa.o3 ... tetrazabicyclo[9.3.1]pentadeca-1(15),11,13-trien-6-yl]-5-(2,3-dihydroxypropylamino)-5-oxopentanoate;gadolinium(3+ …
Matched Iupac: … gadolinium(3+) 2-[6,9-bis({1-carboxylato-3-[(2,3-dihydroxypropyl)carbamoyl]propyl})-3,6,9,15-tetraazabicyclo ... [9.3.1]pentadeca-1(14),11(15),12-trien-3-yl]-4-[(2,3-dihydroxypropyl)carbamoyl]butanoate …
Matched Iupac: … gadolinium(3+) 2-[6,9-bis({1-carboxylato-3-[(2,3-dihydroxypropyl)carbamoyl]propyl})-3,6,9,15-tetraazabicyclo ... [9.3.1]pentadeca-1(14),11(15),12-trien-3-yl]-4-[(2,3-dihydroxypropyl)carbamoyl]butanoate …
Captopril
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … D-2-methyl-3-mercaptopropanoyl-L-proline ... D-3-mercapto-2-methylpropanoyl-L-proline ... (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Fosphenytoin
Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Approved
Investigational
Matched Synonyms: … (3-Phosphoryloxymethyl)phenytoin …
Fluoxetine
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Synonyms: … (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine …
Matched Iupac: … methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine …
Matched Mixtures name: … TARGET 3 MG /25 MG KAPSUL, 90 ADET ... TARGET 3 MG /25 MG KAPSUL, 30 ADET ... FLUXOPIN 3 MG/25 MG KAPSÜL ,30 KAPSÜL …
Matched Iupac: … methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine …
Matched Mixtures name: … TARGET 3 MG /25 MG KAPSUL, 90 ADET ... TARGET 3 MG /25 MG KAPSUL, 30 ADET ... FLUXOPIN 3 MG/25 MG KAPSÜL ,30 KAPSÜL …
Tolnaftate
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate ... Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester ... N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Iupac: … N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Products: … Formula 3 ... Clixit Foot Wipes 3 Pack …
Matched Iupac: … N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Products: … Formula 3 ... Clixit Foot Wipes 3 Pack …
Stiripentol
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
Matched Synonyms: … 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol ... 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Lenalidomide
Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Synonyms: … 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline ... 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione …
Matched Iupac: … 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione …
Matched Iupac: … 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione …
Penciclovir
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Synonyms: … 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine ... 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine ... 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Timolol
Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Synonyms: … (S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol …
Matched Mixtures name: … GANFORT % 0,03 + % 0,5 GÖZ DAMLASI, ÇÖZELTİ, 3 ML …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol …
Matched Mixtures name: … GANFORT % 0,03 + % 0,5 GÖZ DAMLASI, ÇÖZELTİ, 3 ML …
Triprolidine
First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Approved
Matched Synonyms: … (E)-2-[3-(1-pyrrolidinyl)-1-p-toluenepropenyl]pyridine ... trans-1-(2-pyridyl)-3-pyrrolidino-1-p-tolylprop-1-ene ... trans-1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene …
Matched Iupac: … 2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine …
Matched Iupac: … 2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine …
Oxymetazoline
Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Synonyms: … 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline ... 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol ... 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol …
Matched Iupac: … 6-tert-butyl-3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-2,4-dimethylphenol …
Matched Iupac: … 6-tert-butyl-3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-2,4-dimethylphenol …
Benzthiazide
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Synonyms: … 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide ... 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Iupac: … 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Tetrabenazine
A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders. It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008.
Approved
Investigational
Matched Synonyms: … 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one ... 2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine ... 2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine …
Matched Iupac: … 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one …
Matched Iupac: … 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one …
Hydromorphone
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Synonyms: … 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one ... (-)-(5R)-4,5-Epoxy-3-hydroxy-9α-methylmorphinan-6-one ... 4,5alpha-Epoxy-3-hydroxy-17-methyl-6-morphinanone …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure ... 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl ... 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl] …
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl …
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl …
Ferric cation
Iron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. Iron is an essential element involved in various metabolic processes, including oxygen transport, deoxyribonucleic acid (DNA) synthesis, and energy production in electron transport . Resulting from inadequate...
Approved
Matched Synonyms: … iron(3+) …
Matched Iupac: … iron(3+) ion …
Matched Iupac: … iron(3+) ion …
Erythromycin
Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Synonyms: … 3''-O-demethylerythromycin …
Matched Iupac: … (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy …
Matched Mixtures name: … ACNEMIX % 5 + % 3 JEL, 46.6 GR ... BENZADERM %3+%5 TOPİKAL JEL, 46,6 GRAM …
Matched Iupac: … (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy …
Matched Mixtures name: … ACNEMIX % 5 + % 3 JEL, 46.6 GR ... BENZADERM %3+%5 TOPİKAL JEL, 46,6 GRAM …
Fosfomycin
Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae.[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of...
Approved
Matched Synonyms: … (2R-cis)-(3-Methyloxiranyl)phosphonic acid …
Matched Iupac: … [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid …
Matched Description: … [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile …
Matched Products: … MONUROL 3 GM ... FOSTREN® 3 G ... ACECNOU® 3 G …
Matched Iupac: … [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid …
Matched Description: … [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile …
Matched Products: … MONUROL 3 GM ... FOSTREN® 3 G ... ACECNOU® 3 G …
Levonorgestrel
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Synonyms: … 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one ... 17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one ... 13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 5-methyl-3-phenyl-4-isoxazolyl-penicillin ... (5-methyl-3-phenyl-4-isoxazolyl)penicillin ... 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Delavirdine
A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Approved
Matched Synonyms: … (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide ... 2-(4-(5-methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinamine ... N-(2-(1-(3-(isopropylamino)pyridin-2-yl)piperazine-4-carbonyl)-1H-indol-5-yl)methanesulfonamide …
Matched Iupac: … N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide …
Matched Iupac: … N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide …
Diphenoxylate
A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Synonyms: … Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate ... 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester ... Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate …
Matched Iupac: … ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate …
Matched Iupac: … ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate …
Displaying drugs 51 - 75 of 8772 in total