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Displaying drugs 51 - 75 of 11712 in total
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Synonyms: … 2'-Deoxy-5-fluorouridine ... 5-Fluoro-2-desoxyuridine ... 5-fluoro-2'-deoxyuridine …
Matched Iupac: … 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Approved
Matched Synonyms: … 2-Sulfapyridine ... 2-Sulfanilamidopyridin ... 2-Sulfanilamidopyridine …
Matched Iupac: … 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide …
An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Synonyms: … 2-Amino 6MP ... 2-Aminopurin-6-thiol ... 2-Amino-6-purinethiol …
Matched Iupac: … 2-amino-6,7-dihydro-3H-purine-6-thione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Categories: … MATE 2 Substrates …
Matched Products: … DOLPIRID 100 MG/2 ML AMPUL, 6 ADET ... ZEPRID 100 MG/ 2 ML ÇÖZELTİ İÇEREN AMPUL, 6 ADET …
Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 2-(Cyclohexylaminothio)benzothiazole ... Benzothiazyl-2-cyclohexylsulfenamide ... N-cyclohexyl-2-Benzothiazosulfenamide …
Matched Iupac: … N-(1,3-benzothiazol-2-ylsulfanyl)cyclohexanamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched Synonyms: … ]oct-2-ene-2-carboxylic acid ... [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0 …
Matched Iupac: … [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(N-hydroxyimino)acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … (-)-2'-Deoxy-3'-thiacytidine ... 2',3'-Dideoxy-3'-thiacytidine ... 3'-Thia-2',3'-dideoxycytidine …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Matched Synonyms: … (+)-5-Iodo-2'-deoxyuridine ... 2'-Deoxy-5-iodouridine ... 5-iodo-2'-deoxyuridine …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Synonyms: … Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside …
Matched Iupac: … (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]- ... 1-methyl-4-propylpyrrolidine-2-carboxamide …
Matched Salts cas: … 24729-96-2
Matched Mixtures name: … LINDAZOL-2 ® ... LINDAZOL-2 ® ... LINDAZOL-2 PLUSS …
Matched Products: … CLIN 150 MG KAPSUL, 16 ADET ... MENEKLIN 150 MG KAPSÜL, 16 ADET ... CLEOCIN 150 MG KAPSUL, 16 ADET …
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2- ... syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid …
Matched Iupac: … ]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Synonyms: … 2-sulfanilamidopyrimidine ... 2-sulfanilylaminopyrimidine ... N(1)-2-Pyrimidylsulfanilamide …
Matched Iupac: … 4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide …
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Synonyms: … 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidine ... N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide ... (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide …
Matched Iupac: … 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide …
Matched Description: … Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric ... [L11166] Compared to other H2 receptor antagonists, famotidine displays high selectivity towards …
Matched Mixtures name: … ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADET …
Matched Products: … FABOS 20 MG/2 ML ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 2 ADET ... 2 ADET ÇÖZÜCÜ AMPUL ... Zantac 360 2 per blister 6 blisters …
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine ... 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid ... 2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid …
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Synonyms: … 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole …
Matched Iupac: … 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole …
Matched Mixtures name: … PERS-MANT %19 + %2 JEL (30 G) ... EKZE-MANT %0,1 + %2 EMÜLSİYON JEL 30 GR …
Matched Products: … ZARIN CREAM 2% ... MICON CREAM 2% ... TINAZOL CREAM 2% …
Approved
Experimental
Matched Synonyms: … 2-(4-Morpholino)thiobenzothiazole ... 2-Benzothiazolylsulfenylmorpholine ... 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine …
Matched Iupac: … 2-(morpholin-4-ylsulfanyl)-1,3-benzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Synonyms: … [2-(2,6-dichloroanilino)phenyl]acetic acid ... 2-((2,6-dichlorophenyl)amino)benzeneacetic acid …
Matched Iupac: … 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid …
Matched Description: … [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins …
Matched Salts cas: … 78213-16-8 …
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% …
Matched Categories: … Cyclooxygenase-2 (COX-2) Inhibitors ... Non COX-2 selective NSAIDS …
Matched Products: … Pennsaid 16 mg/ml - Lösung zum Auftragen auf die Haut ... Deflamat 2 % - Gel ... VOLTAREN %1 FLASTER, 2 ADET …
Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Synonyms: … Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Products: … Adempas 2 mg film-coated tablet ... PULLMOGUAT® 2 MG TABLETA RECUBIERTA ... ADEMPAS 2 MG FILM KAPLI TABLET , 84 ADET …
An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Approved
Investigational
Matched Synonyms: … 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose ... 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose ... N-D-Glucosyl-(2)-N'-nitrosomethylurea …
Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Approved
Matched Synonyms: … 2-Carbamoylphenol ... 2-Hydroxybenzamide ... 2-Carboxamidophenol …
Matched Iupac: … 2-hydroxybenzamide …
Matched Categories: … Non COX-2 selective NSAIDS …
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Salts cas: … 7085-45-2
Matched Products: … BIPERIDEN-NEURAX 2 MG ... AKINETON 2 MG TABLET, 20 ADET ... AKINETON 2 MG TABLET, 50 ADET …
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Synonyms: … 40-O-(2-hydroxyethyl)-rapamycin ... 42-O-(2-Hydroxyethyl)rapamycin …
Matched Iupac: … 1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2- ... hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa …
Matched Products: … AFINITOR (2 MG DISPERSIBLE TABLETS) …
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2- …
Matched Iupac: … (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic …
Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Approved
Matched Synonyms: … (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl ... )-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure ... ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol ... -5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Synonyms: … 2'-Deoxy-L-thymidine ... β-L-2'-deoxythymidine ... 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil …
Matched Iupac: … 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Synonyms: … 4-(2-benzimidazolyl)thiazole ... 2-(thiazol-4-yl)benzimidazole ... 2-(4-thiazolyl)-1H-benzimidazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Matched Description: … 2-Substituted benzimidazole first introduced in 1962. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 51 - 75 of 11712 in total