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Displaying drugs 726 - 750 of 5334 in total
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Matched Description: … such as [duloxetine] and [venlafaxine]. ... of and response to pain. ... dependence and abuse. …
Matched Mixtures name: … DICLOFENACO SODICO /TRAMADOL HCL 25 MG/25MG. ... DUAMOL 325/37,5 EFERVESAN TABLET, 50 ADET ... Tramadol Hydrochloride and Acetaminophen …
Matched Salts name: … Tramadol hydrochloride
Matched Categories: … tramadol and celecoxib ... tramadol and paracetamol ... tramadol and dexketoprofen ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … TRAMADOL ACIS TROPFEN ... Unidol (Tramadol hydrochloride 50 mg Capsules) ... ZYROTRAM Tramadol Hydrochloride Injection 50 mg/mL …
Investigational
Matched Synonyms: … Sodium ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen ... phosphate - 2-amino-2- (hydroxymethyl)propane-1,3-diol (1/1/1) …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido ... ]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate
Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine ... 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... amine TCAs, such as nortriptyline and desipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Salts name: … Clomipramine hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists ... Drugs that are Mainly Renally Excreted …
Matched Products: … INARYL 50 ... Clomipramine Hydrochloride ... clomiPRAMINE Hydrochloride
Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Approved
Investigational
Matched Description: … After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases ... Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat ... As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. …
Matched Salts cas: … 175865-59-5
Matched Salts name: … Valganciclovir hydrochloride
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors ... Drugs that are Mainly Renally Excreted …
Matched Products: … Apo-valganciclovir ... Valganciclovir Hydrochloride ... Valganciclovir hydrochloride
Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world. The 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 to 2019. Despite this, malaria remains a significant cause of morbidity and...
Approved
Investigational
Matched Synonyms: … alpha-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol …
Matched Description: … 5, refugees in Central and Eastern Africa, nonimmune civilian and military travelers, pregnant women ... [L30623] Mefloquine, commonly known as Lariam, is an antimalarial drug used for the prevention and ... [L30618] Despite this, malaria remains a significant cause of morbidity and mortality; 90% of deaths …
Matched Mixtures name: … อาร์ทีซูเนทและเมฟลอควินไฮโดรคลอไรด์ 25/55 มก. …
Matched Salts name: … Mefloquine hydrochloride
Matched Categories: … artesunate and mefloquine ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Mefloquine Hydrochloride
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Iupac: … 2-[(2,2-dimethylpropanoyl)oxy]-5-[1-hydroxy-2-(methylamino)ethyl]phenyl 2,2-dimethylpropanoate …
Matched Description: … It is available as ophthalmic solution (eye drops). ... Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. …
Matched Salts name: … Dipivefrin hydrochloride
Matched Categories: … Antiglaucoma Preparations and Miotics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Dipivefrin Hydrochloride ... Apo-dipivefrin …
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal ... It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form …
Matched Salts name: … Rabeprazole sodium
Matched Categories: … Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... rabeprazole, amoxicillin and metronidazole ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... rabeprazole, amoxicillin and clarithromycin …
Matched Products: … Ag-rabeprazole ... Apo-rabeprazole ... PARIET TABLET 5MG
A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Approved
Nutraceutical
Matched Synonyms: … Vitamin K3 ... Vitamin K 3 …
Matched Description: … A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted ... to active vitamin K2, menaquinone, after alkylation in vivo. …
Matched Mixtures name: … LIBAVIT-K 20 MG AMPUL, 5 ADET …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Vitamins ... Vitamin K ... Vitamins (Fat Soluble) …
Matched Products: … VITAMIN K 10 MG ... VI-PLEX K 10 MG/2 ML AMPUL, 5 ADET ... VI-PLEX K 10 MG/2 ML AMPUL, 50 ADET …
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Synonyms: … 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole …
Matched Iupac: … 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine …
Matched Description: … Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition. ... Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing ... of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. …
Matched Mixtures name: … ALERTADINA® A TABLETAS RECUBIERTAS …
Matched Salts name: … Tizanidine hydrochloride
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Products: … Apo-tizanidine ... Tizanidine Hydrochloride ... Tizanidine hydrochloride
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... [L12972] Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications …
Matched Salts cas: … 50-98-6 ... 134-72-5
Matched Mixtures name: … BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML ... ColdaeWon Cold A ... ColdaeWon Cough A
Matched Salts name: … Ephedrine hydrochloride
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Adrenergic and Dopaminergic Agents ... Epinephrine and similars ... Alimentary Tract and Metabolism ... Herbs and Natural Products …
Matched Products: … EPHEDRINE HYDROCHLORIDE ... Ephedrine Hydrochloride ... Ephedrine Hydrochloride Tablets 25mg …
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Synonyms: … (3α,,7β)-3,7-dihydroxycholan-24-oic acid ... Ursodeoxycholic acid ... Acido ursodeoxicolico …
Matched Name: … Ursodeoxycholic acid
Matched Iupac: … [a]phenanthren-1-yl]pentanoic acid ... (4R)-4-[(1R,3aS,3bR,4S,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary ... Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Cholagogues and Choleretics …
Matched Products: … ACIDO URSODESOSSICOLICO ABC ... Ag-ursodiol ... PRESTALIX AU
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and
Matched Salts cas: … 547-32-0 …
Matched Salts name: … Sulfadiazine sodium
Matched Categories: … sulfadiazine and tetroxoprim ... Sulfonamides and trimethoprim ... sulfadiazine and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Sulfadiazine Sodium ... LIMISULF® 500 MG TABLETAS ... SULFADIAZINA TABLETAS 500 MG …
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
Approved
Matched Synonyms: … Palmitate ... Palmitic Acid ... Hexadecoic acid
Matched Name: … Palmitic Acid
Matched Iupac: … hexadecanoic acid
Matched Description: … A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. …
Matched Mixtures name: … Huile D'onagre Vitamin E …
Matched Salts name: … 16-chloropalmitic acid
Matched Categories: … Fatty Acids ... Palmitic Acids
Investigational
Matched Synonyms: … fluoro-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide hydrochloride ... )-1-[(3aS,6R,6aR)-6-Ethynyl-3-oxohexahydro-2H-furo[3,2-b]pyrrol-4-yl]-4-methyl-1-oxopentan-2-yl]-4-[5- …
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Iupac: … 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile …
Matched Description: … heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced ... [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer ... drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride
Matched Salts name: … Verapamil hydrochloride
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … VERAPAMIL ACIS 240MG RETAR ... Verapamil Hydrochloride ... Verapamil hydrochloride
Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown.
Approved
Investigational
Matched Synonyms: … IODIZED ETHYL ESTERS OF POPPYSEED FATTY ACIDS
Matched Description: … And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual ... The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed ... Ethiodized oil is used by injection as a radio-opaque contrast agent. …
Matched Categories: … ethyl esters of iodised fatty acids ... Compounds used in a research, industrial, or household setting …
Matched Products: … LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ , 5 ML ... Lipiodol Ultra-Fluide ... LIPIODOL ® ULTRA-FLUIDE
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record ... Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. …
Matched Salts cas: … 120638-55-3 …
Matched Salts name: … Bromfenac sodium
Matched Products: … Bromfenac Sodium ... Apo-bromfenac …
Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine group of sympathomimetic amines. Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem. It is a scheduled drug in most countries due to its high potential for addiction and abuse. The...
Approved
Illicit
Withdrawn
Matched Description: … hydrochloride, a metamfetamine salt. ... Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine ... Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem …
Matched Salts cas: … 51-57-0 …
Matched Salts name: … Metamfetamine hydrochloride
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Drugs that are Mainly Renally Excreted …
Matched Products: … Methamphetamine Hydrochloride
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Approved
Investigational
Matched Iupac: … 16,17-dimethoxy-5,7-dioxa-13lambda5-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2,4 …
Matched Description: … and as antidiarrheal. ... It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections ... An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. …
Matched Products: … Berberine Hydrochloride Granular …
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Iupac: … (1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0 …
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Naltrexone hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … Apo-naltrexone ... Naltrexone Hydrochloride ... Naltrexone Hydrochloride Tablets USP …
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … a-Ketopropionic acid ... alpha-ketopropionic acid ... acide pyruvique …
Matched Name: … Pyruvic acid
Matched Iupac: … 2-oxopropanoic acid
Matched Description: … In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous ... An intermediate compound in the metabolism of carbohydrates, proteins, and fats. …
Matched Salts name: … Sodium pyruvate …
Matched Categories: … Keto Acids ... Carboxylic Acids
Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Approved
Matched Synonyms: … 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine …
Matched Iupac: … (2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane] …
Matched Description: … M1 and M3. ... It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's ... Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors …
Matched Salts name: … Cevimeline hydrochloride
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … Cevimeline Hydrochloride
An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Synonyms: … alpha-Methyladamantanemethylamine ... alpha-Methyl-1-adamantanemethylamine …
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Matched Salts name: … Rimantadine hydrochloride
Matched Categories: … Influenza A M2 Protein Inhibitor ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Rimantadine Hydrochloride
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is...
Approved
Matched Description: … of myasthenia and as a fluorescent probe in HPLC. ... (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment ... A strong organic base existing primarily as guanidium ions at physiological pH. …
Matched Salts cas: … 50-01-1 …
Matched Salts name: … Guanidine hydrochloride
Matched Products: … Guanidine hydrochloride
Displaying drugs 726 - 750 of 5334 in total