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Displaying drugs 726 - 750 of 5231 in total
Cefamandole
Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, cefamandole nafate. It is no longer marketed in the United States.
Approved
Experimental
Matched Synonyms: … (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo ... (6R,7R)-7-(R)-Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0 ... -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}- ... 8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is generally formulated as a formate ester, [cefamandole nafate]. ... It is a parenterally administered broad-spectrum cephalosporin antibiotic. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}- ... 8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is generally formulated as a formate ester, [cefamandole nafate]. ... It is a parenterally administered broad-spectrum cephalosporin antibiotic. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Deslanoside
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
Approved
Matched Synonyms: … (3β,5β,12β)-3-{[β-D-glucopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl ... 3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl …
Matched Iupac: … [a]phenanthren-1-yl]-2,5-dihydrofuran-2-one ... yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta ... hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2- …
Matched Description: … A cardiotonic glycoside from the leaves of Digitalis lanata. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … [a]phenanthren-1-yl]-2,5-dihydrofuran-2-one ... yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta ... hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2- …
Matched Description: … A cardiotonic glycoside from the leaves of Digitalis lanata. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dexmedetomidine
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Salts cas: … 145108-58-3 …
Matched Categories: … Hypnotics and Sedatives ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … DEXDOR 200 MCG/ 2 ML ... DEKSTOMID 200 MCG/2 ML I.V. KONSANTRE INFÜZYON ÇÖZELTISI IÇEREN FLAKON,2 ML ... DEXMEDETOMIDINA 200 MCG/2 ML …
Matched Salts cas: … 145108-58-3 …
Matched Categories: … Hypnotics and Sedatives ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … DEXDOR 200 MCG/ 2 ML ... DEKSTOMID 200 MCG/2 ML I.V. KONSANTRE INFÜZYON ÇÖZELTISI IÇEREN FLAKON,2 ML ... DEXMEDETOMIDINA 200 MCG/2 ML …
Cefalotin
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid ... 7-(Thiophene-2-acetamido)cephalosporin ... 7-(2-Thienylacetamido)cephalosporanic acid …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene ... -2-carboxylic acid …
Matched Description: … Cefalotin is a cephalosporin antibiotic. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … N/A ... CEFALOTINA 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene ... -2-carboxylic acid …
Matched Description: … Cefalotin is a cephalosporin antibiotic. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … N/A ... CEFALOTINA 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Ritlecitinib
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Synonyms: … 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)- …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Description: … Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine ... In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents ... [A260122,A260127] Other kinases have a cysteine at a position equivalent to Cys-909 in JAK3, and several …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Janus Kinase 3, antagonists & inhibitors …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Description: … Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine ... In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents ... [A260122,A260127] Other kinases have a cysteine at a position equivalent to Cys-909 in JAK3, and several …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Janus Kinase 3, antagonists & inhibitors …
Fish oil
Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.
More commonly, fish oil refers to the omega-3-fatty...
Approved
Nutraceutical
Matched Synonyms: … Omega-3 fish oil ... Fish oil containing omega-3 acids …
Matched Description: … Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. ... Furthermore, a variety of studies regarding additional potential actions of fish oil omega-3-fatty acids ... More commonly, fish oil refers to the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic …
Matched Mixtures name: … Cleanse Gut And Colon ... Ultra Omega 3 ... VIVA OMEGA-3 …
Matched Products: … Nature`s Way Kids A+ Omega 3 Fish Oil ... MAGNA Omega 3 ... OMEG-3 1200 Omega 3 Fish oil Concentrate Softgel …
Matched Description: … Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. ... Furthermore, a variety of studies regarding additional potential actions of fish oil omega-3-fatty acids ... More commonly, fish oil refers to the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic …
Matched Mixtures name: … Cleanse Gut And Colon ... Ultra Omega 3 ... VIVA OMEGA-3 …
Matched Products: … Nature`s Way Kids A+ Omega 3 Fish Oil ... MAGNA Omega 3 ... OMEG-3 1200 Omega 3 Fish oil Concentrate Softgel …
Thiamine
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium …
Matched Description: … Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits ... Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS ... and the nervous and digestive systems. …
Matched Mixtures name: … For-2 ... Multi #2 ... Spectrum 2 Cap …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … BEVIGEN 2 ML AMPUL, 3 ADET ... VI-PLEX B1 200 MG/2 ML AMPUL, 3 ADET ... BEFORT B1 AMPUL 250 MG, 3 ADET …
Matched Description: … Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits ... Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS ... and the nervous and digestive systems. …
Matched Mixtures name: … For-2 ... Multi #2 ... Spectrum 2 Cap …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … BEVIGEN 2 ML AMPUL, 3 ADET ... VI-PLEX B1 200 MG/2 ML AMPUL, 3 ADET ... BEFORT B1 AMPUL 250 MG, 3 ADET …
Axicabtagene ciloleucel
Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Matched Description: … The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central ... [A216163]
Axicabtagene ciloleucel was approved by the FDA on October 18th, 2017. ... [L40054] Axicabtagene ciloleucel was later approved by the EMA on August 23, 2018.[L42090] …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Afatinib
Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations...
Approved
Matched Iupac: … -2-enamide ... (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-oxolan-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but …
Matched Description: … Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available ... Gilotrif (afatinib) is the first FDA-approved oncology product from Boehringer Ingelheim [L2939]. ... cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected by an FDA-approved …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available ... Gilotrif (afatinib) is the first FDA-approved oncology product from Boehringer Ingelheim [L2939]. ... cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected by an FDA-approved …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Sotorasib
Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen.[A187547,A187556] It is indicated in the treatment of adult patients with KRAS G12C mutant non-small cell lung cancer. This mutation makes up >50% of all KRAS mutations. Mutant KRAS discovered in 1982 but was not considered a druggable...
Approved
Investigational
Matched Synonyms: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2- methyl ... -4-(prop-2-enoyl)piperazin-1-yl]pyrido[2,3-d]pyrimidin-2(1H)-one …
Matched Iupac: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop ... -2-enoyl)piperazin-1-yl]-1H,2H-pyrido[2,3-d]pyrimidin-2-one …
Matched Description: … [A187547] The drug [MRTX849] is also currently being developed and has the same target. ... [A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop ... -2-enoyl)piperazin-1-yl]-1H,2H-pyrido[2,3-d]pyrimidin-2-one …
Matched Description: … [A187547] The drug [MRTX849] is also currently being developed and has the same target. ... [A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Ceftizoxime
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid ... 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2- …
Matched Iupac: … ]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... It has few side effects and is reported to be safe and effective in aged patients and in patients with ... A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … ]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... It has few side effects and is reported to be safe and effective in aged patients and in patients with ... A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Avanafil
Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved
Matched Synonyms: … (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide …
Matched Iupac: … 4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[(pyrimidin-2 …
Matched Description: … other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and ... Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. ... [vardenafil] but less selectivity than [tadalafil], suggesting a relatively lower risk of visual disturbances …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … STENDRA 100 MG TABLET, 2 ADET ... STENDRA 200 MG TABLET, 2 ADET ... STENDRA 50 MG TABLET, 2 ADET …
Matched Iupac: … 4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[(pyrimidin-2 …
Matched Description: … other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and ... Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. ... [vardenafil] but less selectivity than [tadalafil], suggesting a relatively lower risk of visual disturbances …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … STENDRA 100 MG TABLET, 2 ADET ... STENDRA 200 MG TABLET, 2 ADET ... STENDRA 50 MG TABLET, 2 ADET …
Deferiprone
Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Synonyms: … 1,2-Dimethyl-3-hydroxypyrid-4-one ... 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone …
Matched Iupac: … 3-hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one …
Matched Description: … FDA approved on October 14, 2011. ... Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. ... As a result, erythropoiesis, the production of new red blood cells, is impaired. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … 3-hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one …
Matched Description: … FDA approved on October 14, 2011. ... Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. ... As a result, erythropoiesis, the production of new red blood cells, is impaired. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Janssen COVID-19 Vaccine
The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharmaceutical, and the Beth Israel Deaconess Medical Center. A preclinical study in hamsters infected with...
Approved
Investigational
Matched Description: … 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. ... A preclinical study in hamsters infected with SARS-COV-2 infection[A220053] showed a single immunization ... with the vaccine-elicited neutralizing responses and protected against SARS-CoV-2 induced pneumonia …
Vonoprazan
Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. Furthermore, vonoprazan is 350-times more potent...
Approved
Investigational
Matched Synonyms: … 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine …
Matched Iupac: … {[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]methyl}(methyl)amine …
Matched Description: … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin ... Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+- ... and clarithromycin for the treatment of _H. pylori_ infection. …
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... vonoprazan, amoxicillin and metronidazole ... vonoprazan, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Iupac: … {[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]methyl}(methyl)amine …
Matched Description: … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin ... Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+- ... and clarithromycin for the treatment of _H. pylori_ infection. …
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... vonoprazan, amoxicillin and metronidazole ... vonoprazan, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Cinacalcet
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Synonyms: … (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine ... N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine …
Matched Iupac: … [(1R)-1-(naphthalen-1-yl)ethyl]({3-[3-(trifluoromethyl)phenyl]propyl})amine …
Matched Description: … Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia ... and as Mimpara® in Europe. …
Matched Salts cas: … 364782-34-3 …
Matched Categories: … Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … [(1R)-1-(naphthalen-1-yl)ethyl]({3-[3-(trifluoromethyl)phenyl]propyl})amine …
Matched Description: … Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia ... and as Mimpara® in Europe. …
Matched Salts cas: … 364782-34-3 …
Matched Categories: … Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Nepafenac
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Synonyms: … 2-amino-3-benzoylbenzeneacetamide …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetamide …
Matched Description: … It is used to treat pain and inflammation associated with cataract surgery. ... Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop …
Matched Categories: … Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Products: … NEVANAC 3 MG/ML GÖZ DAMLASI, SÜSPANSİYON …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetamide …
Matched Description: … It is used to treat pain and inflammation associated with cataract surgery. ... Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop …
Matched Categories: … Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Products: … NEVANAC 3 MG/ML GÖZ DAMLASI, SÜSPANSİYON …
Benzthiazide
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Synonyms: … 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide ... 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … Benzthiazide is used to treat hypertension and edema. ... Thiazides also cause loss of potassium and an increase in serum uric acid. ... Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … Benzthiazide is used to treat hypertension and edema. ... Thiazides also cause loss of potassium and an increase in serum uric acid. ... Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key ... Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. ... [A261861] Bedaquiline was approved by the FDA on December 28, 2012, to treat pulmonary MDR-TB, following …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key ... Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. ... [A261861] Bedaquiline was approved by the FDA on December 28, 2012, to treat pulmonary MDR-TB, following …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cevimeline
Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Approved
Matched Synonyms: … 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine …
Matched Description: … M1 and M3. ... Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors ... It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's …
Matched Salts cas: … 153504-70-2 …
Matched Description: … M1 and M3. ... Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors ... It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's …
Matched Salts cas: … 153504-70-2 …
Alverine
Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Approved
Investigational
Matched Synonyms: … N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine ... N,N-Bis(3-phenylpropyl)ethylamine ... N-Ethyl-N-(3-phenylpropyl)benzenepropanamine …
Matched Iupac: … ethylbis(3-phenylpropyl)amine …
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. ... It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Iupac: … ethylbis(3-phenylpropyl)amine …
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. ... It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. …
Matched Categories: … Alimentary Tract and Metabolism …
Riociguat
Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Synonyms: … Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Description: … Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for …
Matched Products: … Adempas 2 mg film-coated tablet ... PULLMOGUAT® 2 MG TABLETA RECUBIERTA ... ADEMPAS 2 MG FILM KAPLI TABLET , 84 ADET …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Description: … Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for …
Matched Products: … Adempas 2 mg film-coated tablet ... PULLMOGUAT® 2 MG TABLETA RECUBIERTA ... ADEMPAS 2 MG FILM KAPLI TABLET , 84 ADET …
Sulpiride
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Description: … [A229683] Sulpiride is not approved by the FDA, Health Canada, or the EMA; though it is approved in ... [A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather …
Matched Categories: … MATE 2 Substrates ... Benzamides and benzamide derivatives …
Matched Products: … DOLPIRID 100 MG/2 ML AMPUL, 6 ADET ... MERESA 100MG / 3 ML ENJEKSİYONLUK ÇÖZLELTİ, 100 ADET ... ZEPRID 100 MG/ 2 ML ÇÖZELTİ İÇEREN AMPUL, 6 ADET …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Description: … [A229683] Sulpiride is not approved by the FDA, Health Canada, or the EMA; though it is approved in ... [A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather …
Matched Categories: … MATE 2 Substrates ... Benzamides and benzamide derivatives …
Matched Products: … DOLPIRID 100 MG/2 ML AMPUL, 6 ADET ... MERESA 100MG / 3 ML ENJEKSİYONLUK ÇÖZLELTİ, 100 ADET ... ZEPRID 100 MG/ 2 ML ÇÖZELTİ İÇEREN AMPUL, 6 ADET …
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … -9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl)ethyl ... (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin …
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic ... [L50181, L50186, L50201] Irinotecan liposome was approved by the FDA in February 2024. …
Matched Salts cas: … 136572-09-3 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Matched Products: … DARITEX-A ... IRINOTEL 40 MG/ 2 ML ... Irinotecan Hydrochloride 40 mg/2 mL …
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic ... [L50181, L50186, L50201] Irinotecan liposome was approved by the FDA in February 2024. …
Matched Salts cas: … 136572-09-3 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Matched Products: … DARITEX-A ... IRINOTEL 40 MG/ 2 ML ... Irinotecan Hydrochloride 40 mg/2 mL …
Fosfomycin
Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae.[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of...
Approved
Matched Synonyms: … (2R-cis)-(3-Methyloxiranyl)phosphonic acid …
Matched Iupac: … [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid …
Matched Description: … [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile ... [A230378] Despite being FDA approved only for urinary tract infections, fosfomycin actually has a broad ... [A230348] In terms of chemical structure, fosfomycin is a phosphoenolpyruvate analog and contains a phosphonic …
Matched Products: … PHOSMYCIN 3 G SAŞE,2 ADET ... FOSDAY 3 G EFERVESAN TABLET, 2 ADET ... URODAY 3 G GRANÜL İÇEREN SASE, 2 ADET …
Matched Iupac: … [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid …
Matched Description: … [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile ... [A230378] Despite being FDA approved only for urinary tract infections, fosfomycin actually has a broad ... [A230348] In terms of chemical structure, fosfomycin is a phosphoenolpyruvate analog and contains a phosphonic …
Matched Products: … PHOSMYCIN 3 G SAŞE,2 ADET ... FOSDAY 3 G EFERVESAN TABLET, 2 ADET ... URODAY 3 G GRANÜL İÇEREN SASE, 2 ADET …
Displaying drugs 726 - 750 of 5231 in total