Displaying drugs 7551 - 7575 of 8198 in total
Efmitermant alfa
Efmitermant alfa, a locally-acting GDF/activin ligand trap, is under investigation in clinical trial NCT03124459 (Study of ACE-083 in Patients With Charcot-marie-tooth Disease).
Investigational
Matched Description: … locally-acting GDF/activin ligand trap, is under investigation in clinical trial NCT03124459 (Study of …
MRK-003
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Description: … It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682] …
AEM-28
AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.
Investigational
Matched Description: … AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as …
ALT-P1
ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Description: … It is under investigation for the treatment of growth hormone deficiency. …
Unasnemab
Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury).
Investigational
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety of …
Elzovantinib
Elzovantinib is under investigation in clinical trial NCT03993873 (Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET).
Investigational
Matched Description: … Elzovantinib is under investigation in clinical trial NCT03993873 (Study of TPX-0022 in Patients With …
Alvocidib
Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
Experimental
Investigational
Matched Description: … Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of …
Iratumumab
Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.
Investigational
Matched Description: … In phase I/II clinical trials for treatment of CD30+ lymphomas. …
Ulimorelin
Ulimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility of the GI tract is severely impaired.
Investigational
Matched Description: … first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility of …
FT-1101
FT-1101 is a novel Bromodomain and Extra-Terminal motif (BET) inhibitor. FT-1101 is under investigation in clinical trial NCT02543879 (Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies).
Investigational
Matched Description: … [A257301] FT-1101 is under investigation in clinical trial NCT02543879 (Study of a Novel BET Inhibitor …
SUVN-502
SUVN-502 is a novel, potent, safe, highly selective and orally active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of cognitive disorders such as Alzheimer’s and Schizophrenia, an unmet medical need.
Investigational
Matched Description: … active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of …
D-Tryptophan
Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG. The D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). The distinguishing...
Experimental
Matched Description: … Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet ... The distinguishing structural characteristic of tryptophan is that it contains an indole functional group …
Desmoteplase
Desmoteplase is a chemical in the saliva of vampire bats. It activates plasminogen to the serine protease, plasmin. Plasmin acts by breaking down fibrin blood clots. When a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting. The enzyme is called DSPA (Desmodus rotundus...
Investigational
Matched Description: … Desmoteplase is a chemical in the saliva of vampire bats. ... Desmoteplase is a recombinant form of vampire bat DSPA (Salivary plasminogen activator alpha 1). …
Oglufanide
Oglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis C viral infection. Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before being acquired by...
Investigational
Matched Description: … Oglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis ... Oglufanide works as a regulator of the body's immune response, is being given by intranasal administration …
Lexacalcitol
Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. It is known to target the vitamin D3 receptor.
Experimental
Matched Description: … This compound belongs to the vitamin D and derivatives class of chemicals. …
Apadenoson
Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies. It is developed by Bristol-Myers Squibb and is in phase II of clinical trials.
Investigational
Matched Description: … It is developed by Bristol-Myers Squibb and is in phase II of clinical trials. …
EP-2104R
EP-2104R is an imaging pharmaceutical under development for the detection of blood clots. It is the first targeted high-resolution technique designed to visualize blood clots directly. It is being developed by EPIX Pharmaceuticals, Inc.
Investigational
Matched Description: … EP-2104R is an imaging pharmaceutical under development for the detection of blood clots. …
ISIS 14803
ISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell culture.
Investigational
Matched Description: … oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of …
Tiletamine
This drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt form, exists as odorless white crystals.
Vet approved
Matched Description: … This drug is a dissociative anesthetic agent that falls under the drug category of _NMDA receptor antagonists …
Garadacimab
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Description: … under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of …
Edodekin alfa
Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or Cannot Be Removed by Surgery).
Investigational
Matched Description: … NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of …
Vonlerolizumab
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Description: … Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination …
AGS-16C3F
AGS 16C3F is an intravenously administered, anti-ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody-drug conjugate. AGS-16C3F is under investigation in clinical trial NCT02639182 (A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma).
Investigational
Matched Description: … AGS-16C3F is under investigation in clinical trial NCT02639182 (A Study of AGS-16C3F vs. …
Tarcocimab tedromer
Tarcocimab tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)).
Investigational
Matched Description: … tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and Safety of …
Pictilisib
Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
Investigational
Matched Description: … Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid …
Displaying drugs 7551 - 7575 of 8198 in total