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Displaying drugs 751 - 775 of 5231 in total
Biperiden
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol ... alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Matched Salts cas: … 7085-45-2 …
Matched Products: … BIPERIDEN-NEURAX 2 MG ... AKINETON 2 MG TABLET, 20 ADET ... AKINETON 2 MG TABLET, 50 ADET …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Matched Salts cas: … 7085-45-2 …
Matched Products: … BIPERIDEN-NEURAX 2 MG ... AKINETON 2 MG TABLET, 20 ADET ... AKINETON 2 MG TABLET, 50 ADET …
Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Categories: … Live Attenuated Influenza A Virus Vaccine …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Categories: … Live Attenuated Influenza A Virus Vaccine …
Medrysone
Medrysone is a corticosteroid used in ophthalmology.
Approved
Matched Iupac: … acetyl-10-hydroxy-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Medrysone is a corticosteroid used in ophthalmology. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Medrysone is a corticosteroid used in ophthalmology. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Cannabidiol
Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact...
Approved
Investigational
Matched Synonyms: … (1'R,2'R)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydrobiphenyl-2,6-diol ... (−)-trans-2-p-mentha-1,8-dien-3-yl-5-pentylresorcinol ... .DELTA.1(2)-TRANS-CANNABIDIOL …
Matched Iupac: … 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol …
Matched Description: … activates 5-HT1A/2A/3A serotonergic and TRPV1–2 vanilloid receptors, antagonizes alpha-1 adrenergic ... 2 (CB1 and CB2)[A32585,A32824]. ... Cannabinoid-2 (CB2R) receptors. …
Matched Categories: … Cannabinoids and similars …
Matched Products: … leafPro CBDmed Oil FS QP 3% ... leafPro CBDmed Oil T-FS QD 3% …
Matched Iupac: … 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol …
Matched Description: … activates 5-HT1A/2A/3A serotonergic and TRPV1–2 vanilloid receptors, antagonizes alpha-1 adrenergic ... 2 (CB1 and CB2)[A32585,A32824]. ... Cannabinoid-2 (CB2R) receptors. …
Matched Categories: … Cannabinoids and similars …
Matched Products: … leafPro CBDmed Oil FS QP 3% ... leafPro CBDmed Oil T-FS QD 3% …
Anisotropine methylbromide
Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary...
Approved
Matched Synonyms: … 8-Methyl-3-(2-propylpentanoyloxy)tropinium bromide ... endo-8,8-Dimethyl-3-((1-oxo-2-propylpentyl)oxy)-8-azoniabicyclo(3.2.1)octane bromide ... 8-Methyltropinium bromide 2-propylvalerate …
Matched Iupac: … 8,8-dimethyl-3-[(2-propylpentanoyl)oxy]-8-azabicyclo[3.2.1]octan-8-ium bromide …
Matched Description: … gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... Anisotropine methylbromide is a quaternary ammonium compound. ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
Matched Iupac: … 8,8-dimethyl-3-[(2-propylpentanoyl)oxy]-8-azabicyclo[3.2.1]octan-8-ium bromide …
Matched Description: … gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... Anisotropine methylbromide is a quaternary ammonium compound. ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
Gadoteric acid
Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Synonyms: … [2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-κ4N1,N4,N7,N10)tetraacetato(3−)]gadolinium …
Matched Iupac: … gadolinium(3+) ion 2-[4,7-bis(carboxylatomethyl)-10-(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl …
Matched Description: … tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with ... kinetic stability, partly due to its macrocyclic structure, and thus has a more favorable safety profile ... [A263141,A263106] Gadoterate is approved by the FDA under the brand name DOTAREM on 20th March 2013 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … gadolinium(3+) ion 2-[4,7-bis(carboxylatomethyl)-10-(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl …
Matched Description: … tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with ... kinetic stability, partly due to its macrocyclic structure, and thus has a more favorable safety profile ... [A263141,A263106] Gadoterate is approved by the FDA under the brand name DOTAREM on 20th March 2013 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
L-Glutamine
A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells. An oral formulation of L-glutamine was approved...
Approved
Investigational
Nutraceutical
Matched Synonyms: … L-2-aminoglutaramic acid ... (2S)-2-amino-4-carbamoylbutanoic acid …
Matched Iupac: … (2S)-2-amino-4-carbamoylbutanoic acid …
Matched Description: … A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes ... An oral formulation of L-glutamine was approved by the FDA in July 2017 for use in sickle cell disease ... It is synthesized from glutamic acid and ammonia. …
Matched Salts cas: … 73477-31-3 …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-amino-4-carbamoylbutanoic acid …
Matched Description: … A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes ... An oral formulation of L-glutamine was approved by the FDA in July 2017 for use in sickle cell disease ... It is synthesized from glutamic acid and ammonia. …
Matched Salts cas: … 73477-31-3 …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Ropeginterferon alfa-2b
Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.[A242000, A242005] Interferon alfa-2b has been used for decades to treat PV but requires frequent dosing...
Approved
Investigational
Matched Description: … [A242010, A242015]
Ropeginterferon alfa-2b was approved by the FDA on November 12, 2021, and is currently ... platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term ... proline-IFN-α-2b in _Escherichia coli_ that has high tolerability and a long half-life. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Sulfadimethoxine
Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Description: … Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully ... Sulfadimethoxine is a sulfonamide antibiotic. ... It is most frequently used in veterinary medicine, although it is approved in some countries for use …
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Omeprazole
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Iupac: … 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin …
Matched Products: … LOSEC A ... OMEPRAZOLO HEXAL A/S ... OMEPRAZOL 1 A PHARMA 20MG …
Matched Description: … Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin …
Matched Products: … LOSEC A ... OMEPRAZOLO HEXAL A/S ... OMEPRAZOL 1 A PHARMA 20MG …
Methoxsalen
A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Synonyms: … 8-methoxy-2',3',6,7-furocoumarin ... 8-methoxy-[furano-3'.2':6.7-coumarin] …
Matched Description: … It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation. ... A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia …
Matched Categories: … Indicators and Reagents ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Compounds used in a research, industrial, or household setting …
Matched Description: … It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation. ... A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia …
Matched Categories: … Indicators and Reagents ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Compounds used in a research, industrial, or household setting …
Phenylbutazone
A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this...
Approved
Vet approved
Matched Description: … A drug that has anti-inflammatory, antipyretic, and analgesic activities. ... It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). …
Matched Categories: … Non COX-2 selective NSAIDS ... phenylbutazone and corticosteroids ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Non COX-2 selective NSAIDS ... phenylbutazone and corticosteroids ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Triprolidine
First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Approved
Matched Synonyms: … (E)-2-[3-(1-pyrrolidinyl)-1-p-toluenepropenyl]pyridine ... trans-1-(2-pyridyl)-3-pyrrolidino-1-p-tolylprop-1-ene ... trans-1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene …
Matched Iupac: … 2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine …
Matched Description: … It is a component of cough and cold medicines. It may cause drowsiness. ... First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. …
Matched Mixtures name: … Ed-A-hist Pse ... A-FERIN DECO ŞURUP, 100 ML ... A-FERIN DECO TABLET, 20 ADET …
Matched Iupac: … 2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine …
Matched Description: … It is a component of cough and cold medicines. It may cause drowsiness. ... First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. …
Matched Mixtures name: … Ed-A-hist Pse ... A-FERIN DECO ŞURUP, 100 ML ... A-FERIN DECO TABLET, 20 ADET …
Bendroflumethiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... bendroflumethiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... bendroflumethiazide and potassium-sparing agents …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... bendroflumethiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... bendroflumethiazide and potassium-sparing agents …
Deserpidine
Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
Approved
Matched Iupac: … methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2( …
Matched Description: … is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and ... antihypertensive properties that has been used for the control of high blood pressure and for the relief …
Matched Categories: … deserpidine and diuretics ... Heterocyclic Compounds, 2-Ring …
Matched Description: … is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and ... antihypertensive properties that has been used for the control of high blood pressure and for the relief …
Matched Categories: … deserpidine and diuretics ... Heterocyclic Compounds, 2-Ring …
Streptozocin
An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Approved
Investigational
Matched Synonyms: … 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose ... 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose ... N-D-Glucosyl-(2)-N'-nitrosomethylurea …
Matched Iupac: … 3-methyl-3-nitroso-1-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea …
Matched Description: … It is used as an antineoplastic agent and to induce diabetes in experimental animals. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 3-methyl-3-nitroso-1-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea …
Matched Description: … It is used as an antineoplastic agent and to induce diabetes in experimental animals. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Thiohexam
Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer.
Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 2-(Cyclohexylaminothio)benzothiazole ... Benzothiazyl-2-cyclohexylsulfenamide ... N-cyclohexyl-2-Benzothiazosulfenamide …
Matched Iupac: … N-(1,3-benzothiazol-2-ylsulfanyl)cyclohexanamine …
Matched Description: … It is also a known allergen and dermatological sensitizer. ... Thiohexam is a rubber cure accelerator. ... Sensitivity to Thiohexam may be identified with a clinical patch test. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N-(1,3-benzothiazol-2-ylsulfanyl)cyclohexanamine …
Matched Description: … It is also a known allergen and dermatological sensitizer. ... Thiohexam is a rubber cure accelerator. ... Sensitivity to Thiohexam may be identified with a clinical patch test. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Flumethasone
Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Approved
Vet approved
Matched Iupac: … (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo …
Matched Description: … This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching ... and vasoconstrictive properties. ... Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic …
Matched Categories: … flumetasone and antiseptics ... flumetasone and antibiotics ... flumetasone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching ... and vasoconstrictive properties. ... Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic …
Matched Categories: … flumetasone and antiseptics ... flumetasone and antibiotics ... flumetasone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Penciclovir
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Synonyms: … 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine ... 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine ... 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. ... Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … EX-LOVIR % 1 KREM 2 G ... PENSIVIR %1 KREM , 2 G ... VECTAVIR % 1 KREM, 2 G …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. ... Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … EX-LOVIR % 1 KREM 2 G ... PENSIVIR %1 KREM , 2 G ... VECTAVIR % 1 KREM, 2 G …
Etoposide
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Synonyms: … O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3' …
Matched Iupac: … (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin …
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. ... Etoposide acts primarily in the G2 and S phases of the cell cycle. …
Matched Salts cas: … 117091-64-2 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … N/A …
Matched Iupac: … (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin …
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. ... Etoposide acts primarily in the G2 and S phases of the cell cycle. …
Matched Salts cas: … 117091-64-2 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … N/A …
Vindesine
Vinblastine derivative with antineoplastic activity against cancer. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Approved
Investigational
Matched Synonyms: … 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine ... 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine …
Matched Description: … Major side effects are myelosuppression and neurotoxicity. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … Major side effects are myelosuppression and neurotoxicity. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Pertuzumab
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Description: … It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant ... domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). …
Matched Categories: … Receptor, ErbB-2, antagonists & inhibitors ... HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Receptor, ErbB-2, antagonists & inhibitors ... HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents …
Cilostazol
Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing...
Approved
Investigational
Matched Synonyms: … 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone ... 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone ... 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one …
Matched Iupac: … 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Description: … Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been ... Cilostazol works by inhibiting both primary and secondary aggregation and reducing calcium-induced contractions …
Matched Categories: … Blood and Blood Forming Organs ... Heterocyclic Compounds, 2-Ring ... Phosphodiesterase 3 Inhibitors ... Compounds used in a research, industrial, or household setting …
Matched Iupac: … 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Description: … Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been ... Cilostazol works by inhibiting both primary and secondary aggregation and reducing calcium-induced contractions …
Matched Categories: … Blood and Blood Forming Organs ... Heterocyclic Compounds, 2-Ring ... Phosphodiesterase 3 Inhibitors ... Compounds used in a research, industrial, or household setting …
Acalabrutinib
To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others.
As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, capsules). This Bruton tyrosine kinase (BTK) inhibitor indicated for the treatment of chronic...
Approved
Investigational
Matched Iupac: … 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide …
Matched Description: … [L10241] In August 2022, the FDA approved a new tablet formulation of Calquence, enabling the co-administration ... or/and that fill an unmet medical need based on a surrogate endpoint. ... As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … [L10241] In August 2022, the FDA approved a new tablet formulation of Calquence, enabling the co-administration ... or/and that fill an unmet medical need based on a surrogate endpoint. ... As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Prednisolone
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Iupac: … 5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, …
Matched Description: … , anti-neoplastic, and vasoconstrictive effects. ... Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... prednisolone and mydriatics ... abiraterone and prednisolone …
Matched Products: … อาร์พี-โซโลน 2 ... PRELONE SYRUP 3 mg/5 ml …
Matched Description: … , anti-neoplastic, and vasoconstrictive effects. ... Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... prednisolone and mydriatics ... abiraterone and prednisolone …
Matched Products: … อาร์พี-โซโลน 2 ... PRELONE SYRUP 3 mg/5 ml …
Displaying drugs 751 - 775 of 5231 in total