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Displaying drugs 776 - 800 of 5231 in total
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/3330/2017 (H1N1) live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure ... 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum ... It is an inhibitor of the A subunit of bacterial DNA gyrase. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Synonyms: … [2-(2,6-dichloroanilino)phenyl]acetic acid ... 2-((2,6-dichlorophenyl)amino)benzeneacetic acid …
Matched Iupac: … 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid …
Matched Description: … [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). ... from a variety of causes. …
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% ... AFTOJEL % 0,1 + %3 JEL (5 G) ... DICLOFEN PROTECT COLMED INTERNATIONAL ® …
Matched Categories: … Cyclooxygenase-2 (COX-2) Inhibitors ... Non COX-2 selective NSAIDS ... diclofenac and antiinfectives ... Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products …
Matched Products: … 3-A OFTENO ... 3- A OFTENO ... Up and Up Arthritis Pain Reliever …
Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body...
Approved
Matched Synonyms: … Calcium glucoheptonate (1:2) …
Matched Description: … Calcium is also needed for the heart, muscles, and nervous system to work properly. ... gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a
Matched Categories: … Alimentary Tract and Metabolism …
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Synonyms: … 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole …
Matched Iupac: … 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine …
Matched Description: … Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing ... Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition. ... of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. …
Matched Mixtures name: … ALERTADINA® A TABLETAS RECUBIERTAS …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Products: … TIZAN 2 ... โทโนไลท์ 2 ... ทีดาร์ 2 มก. …
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched Synonyms: … 2-Nicotinamidoethyl nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate (ester) …
Matched Iupac: … 2-[(pyridin-3-yl)formamido]ethyl nitrate …
Matched Description: … It is not an approved drug by FDA. ... It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by ... Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane …
An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Description: … Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a ... It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac ... of bundle branch block and syncope. …
Matched Categories: … Ajmaline and derivatives ... Heterocyclic Compounds, 2-Ring …
Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Synonyms: … 3-(Carbomethoxy)pyridine ... 3-(Methoxycarbonyl)pyridine ... Methyl 3-pyridinecarboxylate …
Matched Iupac: … methyl pyridine-3-carboxylate …
Matched Description: … muscle and joint pains [F64]. ... Methyl nicotinate is the methyl ester of [DB00627] that is used as an active ingredient as a rubefacient ... The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. …
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Synonyms: … DTP-A
Matched Iupac: … 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetic acid …
Matched Description: … [A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. ... DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … [F4633] T4 and T3 act on nearly every cell of the body, but have a particularly ... of the physiological effects of the thyroid hormones; T4 and T3 have a relative ... [A179935] As a result, many cardiac functions including heart rate, cardiac output, and systemic vascular …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … UGT1A1 Substrates with a Narrow Therapeutic Index ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... levothyroxine sodium and iodine compounds ... Hormones, Hormone Substitutes, and Hormone Antagonists …
The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Synonyms: … Estradiol-17-beta 3-cyclopentyl ether ... 17-alpha-Ethinylestradiol 3-cyclopentyl ether ... 17alpha-Ethynylestradiol 3-cyclopentyl ether …
Matched Iupac: … 9bS,11aS)-7-(cyclopentyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … The 3-cyclopentyl ether of ethinyl estradiol. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … Food and Drug Administration approved Adcetris in March 2018 to treat adult patients with previously ... Brentuximab vedotin was initially approved in 2011. ... and disease. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Synonyms: … 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
Matched Iupac: … 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
Matched Description: … [A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. ... binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's ... [A31328] It is a diarylpyrimidine derivative. …
Matched Salts cas: … 700361-47-3
Matched Categories: … dolutegravir and rilpivirine ... emtricitabine, tenofovir disoproxil and rilpivirine ... emtricitabine, tenofovir alafenamide and rilpivirine …
Dihydroergocristine is part of the ergoloid mixture products. It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline. To know more about ergoloid mixtures, please visit DB01049.
Approved
Experimental
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo[7.3.0.0 …
Matched Description: … [L2637] It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed …
Matched Categories: … Ergot Alkaloids and Derivatives …
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Synonyms: … 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine ... 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine ... 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine …
Matched Iupac: … 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Description: … Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic ... [L6637] Prochlorperazine was first developed in the 1950s [L6643] and was first approved by the FDA in ... of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Iupac: … ,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH …
Matched Description: … Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone …
Matched Mixtures name: … Point Of Care LM DEP 2
Matched Categories: … Compounds used in a research, industrial, or household setting ... Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives …
Matched Products: … PREDNOL-L 40 MG LİYOFİLİZE ENJEKTABL AMPUL, 3 ADET ... PARA RECONSTITUIR A 4 ML. DE SOLUCIÓN INYECTABLE.I.M.. I.V. LENTA . NFUSIÓN I.V. …
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Approved
Investigational
Matched Synonyms: … 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin ... deamino-2-O-methyltyrosine-1-carbaoxytocin ... 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin …
Matched Iupac: … [(4-methoxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaazacycloicosane-3-carbonyl]pyrrolidin ... (2S)-2-{[(2S)-1-[(3R,6S,9S,12S,15S)-12-[(2S)-butan-2-yl]-9-(2-carbamoylethyl)-6-(carbamoylmethyl)-15- ... -2-yl]formamido}-N-(carbamoylmethyl)-4-methylpentanamide …
Matched Description: … Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. ... It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Oxytocin and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and ... insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal ... used and effective medication for a variety of indications, contemporary advancements in the formulation …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … Meval 2 ... STESOLID 2 ... DIAPINE TABLET 2 mg …
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Synonyms: … 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide …
Matched Iupac: … 7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine-1,1-dione …
Matched Description: … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels ... In September 2015, the FDA issued a safety alert regarding post-marketing reports of pulmonary hypertension ... and electrolyte disturbances. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.[A191688,A191721] The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes.[A191688,A191772,A191775] Not only does favipiravir inhibit...
Approved
Investigational
Matched Iupac: … 6-fluoro-3-hydroxypyrazine-2-carboxamide …
Matched Description: … ., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic ... [A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but ... the drug has shown promise in the treatment of avian influenza, and may be an alternative option for …
A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Approved
Vet approved
Matched Description: … A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive …
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … (3-hydroxyphenyl)dimethylethylammonium ... 3-hydroxy-N,N-dimethyl-N-ethylanilinium ... N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Matched Iupac: … N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Matched Description: … A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It also consists up to 4% linoleic, 3% oleic, 1% stearic, and less than 1% linolenic fatty acids [A31170 ... It is an FDA-approved food additive directly added to food products for human consumption. ... It can also be found in hard candies as a release agent and anti-sticking agent, or supplementary vitamins …
Matched Mixtures name: … Zinc and Castor Oil Crm ... Zinc and Castor Oil Cream BP …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Castor Oil …
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Synonyms: … BMP 2 ... BMP-2 ... rhBMP-2
Matched Description: … Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant ... In 2004, it was approved by the FDA and is marketed as Infuse. ... BMP-2 is a potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Synonyms: … 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline ... 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine …
Matched Iupac: … 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Description: … Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. ... Prazosin is a drug used to treat hypertension. ... evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and
Matched Categories: … Heterocyclic Compounds, 2-Ring ... prazosin and diuretics ... Alpha-Adrenoreceptor Antagonists and Diuretics …
Matched Products: … ATODEL 2 TABLET 2 mg ... ไบเพรส 2 ... กาเพรส 2
Displaying drugs 776 - 800 of 5231 in total