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Displaying drugs 801 - 825 of 1105 in total

MRK-003

MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Synonyms: … 1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators ... Sulfur Compounds …

Neomycin

Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer...
Approved
Vet approved
Matched Description: … [A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its ... [L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. ... [A191529] Neomycin B, also known as [framycetin], is the most active component of the complex and neomycin …
Matched Mixtures name: … DEXAMETASONA SODIO FOSFATO 1.3 MG/ML. SOLUCIÓN OFTÁLMICA ESTÉRIL. ... DEXAMETASONA SODIO FOSFATO+ POLIMIXINA B SULFATO + NEOMICINA SULFATOSOLUCION OFTALMICA ... NEOMICINA SULFATO 3.5 MG + DEXAMATASONA SODIO FOSFATO 1.3MG + POLIMIXINA B SULFATO 6.600U.I / ML SOLUCION …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Antiinfectives and Antiseptics for Local Oral Treatment ... Ophthalmological and Otological Preparations …
Matched Products: … Pomada de Sulfa ... Pomada Sulfa First Aid Antibiotic …

Sodium lauryl sulfoacetate

Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.
Approved
Experimental
Matched Synonyms: … Sulfoacetic acid dodecyl ester S-sodium salt …
Matched Name: … Sodium lauryl sulfoacetate …
Matched Iupac: … sodium 2-(dodecyloxy)-2-oxoethane-1-sulfonate …
Matched Description: … Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products. …
Matched Categories: … Alimentary Tract and Metabolism ... sodium lauryl sulfoacetate, incl. combinations …

CP-271485

Experimental
Matched Synonyms: … (6S)-4-Benzyl-6-(1-methyl-2,2-dioxido-1,3-dihydro-2,1-benzothiazol-5-yl)-3-morpholinone …

Sulpiride

Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … SULPIR 50 MG KAPSUL, 15 ADET ... SULPIR 50 MG KAPSUL, 30 ADET …

5-phospho-D-arabinohydroxamic acid

Experimental
Matched Synonyms: … (2R,3R,4S)-2,3,4-Trihydroxy-5-(hydroxyamino)-5-oxopentyl dihydrogen phosphate …

3'-Uridinemonophosphate

Experimental
Matched Synonyms: … Uridine 3'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Fosphenytoin

Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Approved
Investigational
Matched Description: … Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium ... channels, and therefore limit repetitive firing of action potentials. …
Matched Salts name: … Fosphenytoin sodium …
Matched Categories: … Phenytoin and Prodrugs ... Sodium Channel Blockers …
Matched Products: … Fosphenytoin Sodium ... Fosphenytoin sodium …

Secobarbital

Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Description: … Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate ... derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. …
Matched Salts name: … Secobarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Seconal Sodium ... Seconal Sodium Pulvule 240 0.1gm …

Neoarsphenamine

Investigational
Withdrawn
Matched Synonyms: … Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylate ... Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium …
Matched Iupac: … sodium {[({5-[(1E)-2-(3-amino-4-hydroxyphenyl)diarsen-1-yl]-2-hydroxyphenyl}amino)methoxy]sulfanyl}olate …

Guanosine 3'-monophosphate

Experimental
Matched Synonyms: … Guanosine 3'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Fusidic acid

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …
Matched Salts name: … Fucidate sodium …
Matched Products: … AFUSIL TOPIC® ... FUSIDATO DI SODIO ISDIN ... Axcel Sodium Fusidate 250 Tablet …

Calcium lactate gluconate

Experimental
Matched Name: … Calcium lactate gluconate …
Matched Mixtures name: … CALCIUM SANDOZ ... CALCIUM SANDOZ FORTE ... CALCIUM SANDOZ FORTE …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium Salts ... calcium lactate gluconate …

Tetradecyl hydrogen sulfate (ester)

Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids and varicose veins . Sodium tetradecyl sulfate has been widely used since the 1950s, and in...
Approved
Matched Description: … Sodium tetradecyl sulfate has been widely used since the 1950s, and in 1978 the first successful report ... in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids ... and varicose veins [L2031]. …
Matched Products: … Sodium Tetradecyl Sulfate ... (sotradecol) Sodium Tetradecyl Sulfate …

Trichloroethylene

Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. It has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic and as an inhaled obstetrical analgesic. Environmental exposure,...
Approved
Matched Synonyms: … trichlor …
Matched Description: … It has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic ... , is a major concern for human health and has been the subject of numerous incidents and lawsuits. ... and as an inhaled obstetrical analgesic. …

Ferric sodium citrate

Experimental
Matched Name: … Ferric sodium citrate …
Matched Iupac: … iron(3+) ion sodium 2-oxidopropane-1,2,3-tricarboxylate …
Matched Categories: … Blood and Blood Forming Organs ... ferric sodium citrate …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Description: … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially …
Matched Salts name: … Chloramphenicol sodium succinate …
Matched Products: … Chloromycetin Sodium Succinate ... Chloramphenicol Sodium Succinate ... CHLORAMPHENICOL SODIUM SUCCINATE …

Miltefosine

Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease. It can be administered topically or orally and...
Approved
Investigational
Matched Synonyms: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Iupac: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Description: … It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of ... It can be administered topically or orally and is only indicated in patients aged 12 years or older. ... first line treatment for free-living amebae (FLA) infections such as primary amebic meningoencephalitis and …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …

Adenosine 5'-methylenediphosphate

Experimental
Matched Synonyms: … Adenosine 5'-(hydrogen (phosphonomethyl)phosphonate) ... Adenosine, 5'-(trihydrogen methylenebis(phosphonate)) …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Aminohippuric acid

The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory …
Matched Salts name: … Aminohippurate sodium …
Matched Categories: … Benzamides and benzamide derivatives ... Indicators and Reagents ... Tests for Renal Function and Ureteral Injuries …
Matched Products: … Aminohippurate Sodium Pah ... Aminohippurate Sodium Inj Liq 20% …

Nitrous acid

Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Matched Description: … applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and ... Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to …
Matched Salts name: … Sodium nitrite …
Matched Categories: … Diet, Food, and Nutrition ... Indicators and Reagents ... sodium nitrite ... Sodium Compounds …
Matched Products: … Sodium Nitrite ... Sodium Nitrite Injection, USP …

Hypochlorite

Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. ... Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and ... Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions. …
Matched Salts name: … Sodium hypochlorite …
Matched Categories: … Antiseptics and Disinfectants ... Chlorine Compounds ... Sodium Compounds ... sodium hypochlorite …
Matched Products: … Sodium hypochlorite disinfectant ... (Qiqing) Sodium Hypochlorite Disinfectant …

1-deoxy-1-{2,6,8-trioxo-7-[4-(phosphonooxy)butyl]-1,2,3,6,7,8-hexahydro-9H-purin-9-yl}-D-arabinitol

Experimental
Matched Synonyms: … 4-[2,6,8-trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]butyl dihydrogen phosphate …

Bisphosphocin Nu-3

Bisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).
Investigational
Matched Synonyms: … 3'-thymidylic acid, monobutyl ester, 5'-(butyl hydrogen phosphate) …

Methohexital

An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Salts name: … Methohexital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Brevital Sodium ... Brietal Sodium Ampoule 660 …
Displaying drugs 801 - 825 of 1105 in total