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Displaying drugs 801 - 825 of 991 in total

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Salts name: … Loxapine hydrochloride …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Loxapine Hydrochloride Im Injection 50mg/ml ... Loxapine Hydrochloride Oral Concentrate 25mg/ml …

Triprolidine

First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Approved
Matched Synonyms: … (E)-2-[3-(1-pyrrolidinyl)-1-p-toluenepropenyl]pyridine …
Matched Iupac: … 2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine …
Matched Description: … First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. ... It is a component of cough and cold medicines. It may cause drowsiness. …
Matched Mixtures name: … TRIFEN 100 ML SUS. ... Mucinex Nightshift Cold and Flu Clear and Cool ... CVS Maximum Strength Severe Congestion and Cough Overnight Cold and Flu Clear and cool …
Matched Salts name: … Triprolidine hydrochloride ... Triprolidine hydrochloride monohydrate …
Matched Products: … Triprolidine Hydrochloride …

Ethambutol

Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and …
Matched Salts name: … Ethambutol hydrochloride …
Matched Categories: … ethambutol and isoniazid ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Matched Products: … Ethambutol Hydrochloride ... ETHAMBUTOL HYDROCHLORIDE …

TP-3654

Investigational
Matched Synonyms: … 2-(trans-4-((3-(3-(trifluoromethyl)phenyl)imidazo[1,2-b]pyridazin6-yl)amino)cyclohexyl)propan-2-ol hydrochloride …
Matched Salts name: … TP-3654 hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Demeclocycline

A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Description: … A tetracycline analog having a 7-chloro and a 6-methyl. …
Matched Salts name: … Demeclocycline hydrochloride …
Matched Products: … Demeclocycline Hydrochloride …

Dextropropoxyphene

Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. ... It displays antitussive and local anaesthetic actions. ... been withdrawn from the market in Europe and the United States. …
Matched Mixtures name: … Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen …
Matched Salts name: … Dextropropoxyphene hydrochloride …
Matched Products: … Propoxyphene Hydrochloride …

Guanfacine

Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Salts name: … Guanfacine hydrochloride …
Matched Products: … Guanfacine hydrochloride ... Guanfacine Hydrochloride …

Oxycodone

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Description: … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as …
Matched Mixtures name: … Oxycodone Hydrochloride and Aspirin ... Oxycodone Hydrochloride and Ibuprofen ... Oxycodone Hydrochloride and Ibuprofen …
Matched Salts name: … Oxycodone hydrochloride …
Matched Categories: … oxycodone and naloxone ... oxycodone and naltrexone ... oxycodone and ibuprofen ... oxycodone and paracetamol ... oxycodone and acetylsalicylic acid …
Matched Products: … Oxycodone Hydrochloride ... Oxycodone Hydchloride ... Oxycodone hydrochloride …

Duloxetine

Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Description: … [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. ... Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. ... Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more. …
Matched Salts name: … Duloxetine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Duloxetine hydrochloride ... Duloxetine Hydrochloride ... Duloxetine Hydrochloride 20 mg …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. …
Matched Salts name: … Procaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Procaine Hydrochloride …

PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole

Experimental
Matched Name: … PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole …

Deferiprone

Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Synonyms: … 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone …

Tomivosertib

Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Investigational
Matched Synonyms: … 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'- …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine …
Matched Description: … investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and …
Matched Salts name: … Tomivosertib hydrochloride …

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …

Prazosin

Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Description: … Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. ... evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and …
Matched Salts name: … Prazosin hydrochloride …
Matched Categories: … Alpha-Adrenoreceptor Antagonists and Diuretics ... prazosin and diuretics …
Matched Products: … Prazosin Hydrochloride ... Prazosin hydrochloride …

Propofol

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … for induction and/or maintenance of anaesthesia prior to and during surgeries. ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia ... Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … PROPOFOL-LIPURO 1% GLASS BOTTLE ... PROPOFOL-LIPURO 1% (20ML GLASS AMPOULE) …

EDIT-101

EDIT-101 is a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein 9) gene editing constructs.
Investigational
Matched Synonyms: … a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR/Cas9 (clustered …
Matched Description: … EDIT-101 is a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Salts name: … Lurasidone hydrochloride …
Matched Products: … Lurasidone Hydrochloride ... Lurasidone hydrochloride …

Doxepin

Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but...
Approved
Investigational
Matched Description: … Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. ... [T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer ... [L5977] Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. …
Matched Salts name: … Doxepin hydrochloride …
Matched Categories: … Antipruritics and Local Anesthetics ... Hypnotics and Sedatives ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Doxepin Hydrochloride ... Doxepin hydrochloride …

Venlafaxine

Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and …
Matched Salts name: … Venlafaxine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Venlafaxine hydrochloride ... Venlafaxine Hydrochloride ... Venlafaxine Hydrochloride ER …

Levosalbutamol

Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Salbutamol has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has...
Approved
Investigational
Matched Description: … , or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and ... The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects …
Matched Salts name: … Levosalbutamol hydrochloride …
Matched Products: … Levalbuterol Hydrochloride …

Quinapril

Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure.[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Quinapril was granted FDA approval...
Approved
Investigational
Matched Description: … [L8420,L8423] It is used to treat hypertension and heart failure. …
Matched Mixtures name: … Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Quinapril Hydrochloride …
Matched Categories: … ACE Inhibitors and Diuretics ... quinapril and diuretics …
Matched Products: … Quinapril Hydrochloride …

G100

Investigational
Matched Synonyms: … GLA-SE …

Nedometinib

Investigational
Matched Synonyms: … 2-((2-fluoro-4-iodophenyl)amino)-n-(2-hydroxyethoxy)-1-methyl-1h-pyrrolo(2,3-b)pyridine-3-carboxamide …
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide …
Displaying drugs 801 - 825 of 991 in total