Displaying drugs 826 - 850 of 1170 in total
Cilastatin
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine ... (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2- …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Tovorafenib
Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements. BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation,...
Approved
Investigational
Matched Synonyms: … 6-Amino-5-chloro-N-((1R)-1-(5-(((5-chloro-4-(trifluoromethyl)-2-pyridinyl)amino)carbonyl)-2-thiazolyl ... Pyrimidinecarboxamide, 6-amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl ... 6-amino-5-chloro-N-[1R)-1-[5-[[[5-hloro-4-(trifluoromethyl)-2pyridinyl]amino]carbonyl]-2-thiazoyl]ethyl …
Matched Description: … growth and survival. ... [A263602] Tovorafenib inhibits BRAF and blocks dysregulated signalling pathways related to cancer cell ... [L50587] BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation, and differentiation …
Matched Description: … growth and survival. ... [A263602] Tovorafenib inhibits BRAF and blocks dysregulated signalling pathways related to cancer cell ... [L50587] BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation, and differentiation …
7-alpha-D-Ribofuranosyl-2-aminopurine-5'-phosphate
Experimental
Matched Name: … 7-alpha-D-Ribofuranosyl-2-aminopurine-5'-phosphate …
1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate
Experimental
Matched Name: … 1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate …
Enapotamab vedotin
Enapotamab vedotin is under investigation in clinical trial NCT02988817 (Enapotamab Vedotin (Humax-axl-adc) Safety Study in Patients With Solid Tumors).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human growth factor receptor axl)(human humax-axl .gamma.1-chain), disulfide …
Doxycycline
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Salts name: … Doxycycline calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Vibramycin Calcium …
Matched Salts name: … Doxycycline calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Vibramycin Calcium …
2-chloroethyl-3-sarcosinamide-1-nitrosourea
2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Synonyms: … ACETAMIDE, 2-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)METHYLAMINO)- …
Matched Description: … Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific. ... sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and …
Matched Description: … Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific. ... sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and …
Ticarcillin
An antibiotic derived from penicillin similar to carbenicillin in action.
Approved
Investigational
Vet approved
Matched Synonyms: … α-carboxy-3-thienylmethylpenicillin ... (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Zamerovimab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 1a9 .gamma.1-chain), disulfide …
Terazosin
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Synonyms: … 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine …
Matched Iupac: … 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine …
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Iupac: … 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine …
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones …
Atibuclimab
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Befovacimab
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human tissue factor pathway inhibitor) (human monoclonal 1093884 .gamma.2-chain), disulfide …
Ezabenlimab
Investigational
Matched Synonyms: … -proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 .gamma.4-chain), disulfide …
Zimberelimab
Investigational
Matched Synonyms: … 231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 .gamma.4-chain), disulfide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … α-D-ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Matched Categories: … Sugar Phosphates …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Matched Categories: … Sugar Phosphates …
Lercanidipine
Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched International brands: … Carmen …
Matched Description: … Lercanidipine is a calcium channel blocker of the dihydropyridine class. …
Matched Mixtures name: … CARMEN ACE 10MG/10MG ... CARMEN ACE 10MG/10MG ... CARMEN ACE 10MG/10MG …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... valsartan and lercanidipine ... enalapril and lercanidipine …
Matched Products: … CARMEN 10MG ... CARMEN 20MG …
Matched Description: … Lercanidipine is a calcium channel blocker of the dihydropyridine class. …
Matched Mixtures name: … CARMEN ACE 10MG/10MG ... CARMEN ACE 10MG/10MG ... CARMEN ACE 10MG/10MG …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... valsartan and lercanidipine ... enalapril and lercanidipine …
Matched Products: … CARMEN 10MG ... CARMEN 20MG …
Diclofenac
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol Delayed-Release …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... CareOne arthritis pain relief …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol Delayed-Release …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... CareOne arthritis pain relief …
GO-203-2C
GO-203-2C is under investigation in clinical trial NCT02204085 (A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … Acetyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-cysteinyl-D-glutaminyl-D-cysteinyl-D-arginyl-D-arginyl-D-lysyl-dasparaginylamide disulfide …
N-[(BENZYLOXY)CARBONYL]-L-CYSTEINYLGLYCINE
Experimental
Matched Name: … N-[(BENZYLOXY)CARBONYL]-L-CYSTEINYLGLYCINE …
Matched Iupac: … 2-[(2R)-2-{[(benzyloxy)carbonyl]amino}-3-sulfanylpropanamido]acetic acid …
Matched Iupac: … 2-[(2R)-2-{[(benzyloxy)carbonyl]amino}-3-sulfanylpropanamido]acetic acid …
Prephenic acid
Experimental
Matched Synonyms: … cis-1-Carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1-propanoic acid …
Matched Iupac: … (1s,4s)-1-(2-carboxy-2-oxoethyl)-4-hydroxycyclohexa-2,5-diene-1-carboxylic acid …
Matched Iupac: … (1s,4s)-1-(2-carboxy-2-oxoethyl)-4-hydroxycyclohexa-2,5-diene-1-carboxylic acid …
Edotreotide
Investigational
Matched Synonyms: … d-phenylalanyl-l-cysteinyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-threonyl-n-((1r,2r)-2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic(2->7)-disulfide ... acetyl-d-phenylalanyl-l-cysteinyl-l-tyrosyl-d-tryprophyl-l-lysyl-l-threonyl-n-((1r,2r)-2-hydroxy-1-(hydroxymethyl)propyl)-l-cysteinamide cyclic (2->7)-disulfide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents …
Tinlarebant
Investigational
Matched Synonyms: … 1-(3-(4-(3,4-difluoro-2-(trifluoromethyl)phenyl)piperidine-1-carbonyl)-1h,4h,5h,6h,7h-pyrazolo(3,4-c) ... 1-(3-{4-[3,4-Difluoro-2-(Trifluoromethyl)Phenyl]Piperidine-1-Carbonyl}-1H,4H,5H,6H,7H-Pyrazolo[3,4-C] ... Ethanone, 1-(3-((4-(3,4-difluoro-2-(trifluoromethyl)phenyl)-1-piperidinyl)carbonyl)-1,4,5,7-tetrahydro …
Matched Iupac: … 1-(3-{4-[3,4-difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl}-1H,4H,5H,6H,7H-pyrazolo[3,4-c] …
Matched Iupac: … 1-(3-{4-[3,4-difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl}-1H,4H,5H,6H,7H-pyrazolo[3,4-c] …
Quisovalimab
Investigational
Matched Synonyms: … tumor necrosis factor superfamily protein TNFSF14) (human-Mus musculus monoclonal SAR252067 γ4-chain), disulfide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
PARPI F-18
PARPI F-18 is a diagnostic agent under investigation for use in the management of glioblastoma multiforme.
Investigational
Matched Synonyms: … 1(2h)-phthalazinone, 4-((4-fluoro-3-((4-(4-(fluoro-18f)benzoyl)-1-piperazinyl)carbonyl)phenyl)methyl) …
Matched Iupac: … 4-[(4-fluoro-3-{4-[4-(18F)fluorobenzoyl]piperazine-1-carbonyl}phenyl)methyl]-1,2-dihydrophthalazin-1- …
Matched Iupac: … 4-[(4-fluoro-3-{4-[4-(18F)fluorobenzoyl]piperazine-1-carbonyl}phenyl)methyl]-1,2-dihydrophthalazin-1- …
Urtoxazumab
Investigational
Matched Synonyms: … -chain), disulfide with human-mouse monoclonal huvtm1.1 .kappa.-chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 826 - 850 of 1170 in total