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Displaying drugs 826 - 850 of 1379 in total
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … Tedizolid phosphate ... Torezolid phosphate ... fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
Matched Name: … Tedizolid phosphate
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and
Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and...
Experimental
Investigational
Matched Synonyms: … Anhydrous tenofovir ... Tenofovir anhydrous ... Tenofovir (anhydrous) …
Matched Description: … [A37693] In the most strict sense and due to the fact that it presents a phosphate group bound to the ... [A37693] The antiviral activities of tenofovir were first reported in 1993 and this agent was commercially ... available since 2008 in the form of [tenofovir disoproxil] and [tenofovir alafenamide] in order to obtain …
Matched Categories: … Tenofovir and prodrugs …
Experimental
Matched Name: … Sodium nitrate …
Matched Iupac: … sodium nitrate …
Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti.
Approved
Matched Synonyms: … Difluoroprednisolone butyrate acetate
Matched Description: … Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated ... It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. ... Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People With Pulmonary Hypertension Who Have Impaired RV Function. Using Imaging Studies PET Scan and Cardiac MRI.).
Investigational
Matched Synonyms: … 11C-ACETATE
Matched Description: … Using Imaging Studies PET Scan and Cardiac MRI.). ... Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and
Experimental
Matched Synonyms: … Xylitol 5-phosphate
Matched Name: … L-xylitol 5-phosphate
Matched Categories: … Sugar Phosphates
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Synonyms: … 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide ... 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Matched Description: … Thiazides also cause loss of potassium and an increase in serum uric acid. ... Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in ... Benzthiazide is used to treat hypertension and edema. …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Approved
Matched Salts name: … Mivacurium chloride
Matched Categories: … mivacurium chloride
Matched Products: … Mivacurium Chloride
Experimental
Matched Synonyms: … Erythose-4-phosphate
Matched Name: … D-erythrose 4-phosphate
Motexafin lutetium (MLu) is a second-generation photosensitizer for photodynamic therapy (PDT) of cancer. It belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. Motexafin lutetium is a pentadentate aromatic metallotexaphyrin with photosensitizing properties.
Investigational
Matched Synonyms: … Lutetium texaphyrin anhydrous ... Motexafin lutetium anhydrous
Experimental
Matched Synonyms: … β-D-glucose 6-phosphate ... beta-D-glucose-6-phosphate ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate
Sodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes including the production of rubber chemicals, sulfur dyes and oil recovery. Along with its hydrate form, sodium sulfide releases hydrogen...
Approved
Matched Name: … Sodium sulfide …
Matched Description: … Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various ... However the clinical significance and mechanism of action of sodium sulfide and replication of results ... Along with other sulfides, the anti-inflammatory and tissue-protective effects of sodium sulfide have …
Matched Products: … Sodium Sufide …
Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient. It acts as an emulsifier and pH...
Approved
Matched Synonyms: … sodium L-tartrate …
Matched Name: … Sodium tartrate …
Matched Description: … , and odorless crystals. ... It acts as an emulsifier and pH control agent in food products [L2590]. ... This compound is commonly used as an emulsifier in cheese/cheese spread products and is not to exceed …
Matched Categories: … Alimentary Tract and Metabolism ... sodium tartrate …
Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. Levacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased...
Approved
Investigational
Withdrawn
Matched Synonyms: … Levomethadyl acetate ... Levo-methadyl acetate ... (1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate
Matched Iupac: … (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate
Matched Description: … Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. …
Approved
Investigational
Matched Synonyms: … Black lead
Experimental
Matched Name: … Propyl acetate
Matched Iupac: … propyl acetate
[methyltelluro]acetate is a solid. This compound belongs to the organic oxoanionic compounds. These are organic compounds containing an oxoanion. This medication targets the protein monomeric sarcosine oxidase.
Experimental
Matched Name: … [Methyltelluro]Acetate
Matched Iupac: … 2-(methyltellanyl)acetate
Matched Description: … [methyltelluro]acetate is a solid. This compound belongs to the organic oxoanionic compounds. …
Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Synonyms: … Telapristone acetate
Matched Name: … Telapristone acetate
Matched Iupac: … methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … to alleviate symptoms associated with both uterine fibroids and endometriosis. ... Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development …
Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Approved
Investigational
Matched Synonyms: … Nomegestrol acetate ... 17-alpha-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate
Matched Name: … Nomegestrol acetate
Matched Iupac: … acetyl-5,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … therapy, and for the treatment of gynecological disorders. ... Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) …
Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins . It mediates progestational activity 100 times higher than that of progesterone ....
Approved
Experimental
Investigational
Matched Synonyms: … Segesterone acetate ... 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate
Matched Name: … Segesterone acetate
Matched Iupac: … methylidene-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative ... Segesterone acetate binds selectively to progesterone receptors and not androgen receptors [A37083]. ... On August 10, 2018, Annovera™ containing segesterone acetate and [ethinyl estradiol] was granted approval …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Iodamide is a contrast medium molecule that is no longer marketed in the United States.
Withdrawn
Matched Synonyms: … Iodamide
Matched Name: … Iodamide
Matched Description: … Iodamide is a contrast medium molecule that is no longer marketed in the United States. …
Matched Salts name: … Iodamide meglumine …
Matched Categories: … iodamide
Matched Products: … UROMIRO 300 SODICO
Experimental
Matched Synonyms: … α-D-mannose 6-phosphate ... alpha-D-Mannopyranose 6-phosphate
Matched Name: … alpha-D-mannose 6-phosphate
Experimental
Matched Name: … Iodine (131I) norcholesterol …
Matched Categories: … Iodine (131I) Compounds ... iodine (131I) norcholesterol …
Investigational
Matched Synonyms: … Iodine I 131 apamistamab ... Iodine (131i) apamistamab ... monoclonal BC8 gamma1-chain), disulfide with mus musculus monoclonal BC8 kappa-chain, dimer, labeled with iodine
Matched Name: … Apamistamab iodine I-131 …
Experimental
Matched Synonyms: … Aloe barbadensis leaf polysaccharides ... Aloe vera (l.) burm.f. leaf polysaccharides …
Matched Name: … Aloe vera leaf polysaccharides …
Matched Mixtures name: … Iodoquinol, Hydrocortisone Acetate, Aloe Polysaccharides ... Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1% …
Displaying drugs 826 - 850 of 1379 in total